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> Protein (NX_P78417)
Protein (NX_P78417)
Protein
Gene SymbolGSTO1 to neXtProt (NX_P78417)
DescriptionGlutathione S-transferase omega-1
Chromosome10
Location10q25.1 (105995114 ~ 106027217) to Ensembl
Sequene Features : Isoforms 3, Variants 32, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.glutathione derivative biosynthetic process
.cellular response to arsenic-containing substance
.positive regulation of ryanodine-sensitive calcium-release channel activity
  + 8 more...
.methylarsonate reductase activity
.glutathione dehydrogenase (ascorbate) activity
.oxidoreductase activity
.glutathione transferase activity
.extracellular exosome
.cytosol
.cytoplasm
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
3 32 9
2014-09-19protein level
3 28 9
2014-05-27protein level
3 28 9
2014-02-25protein level
3 28 9
2013-12-09protein level
3 19 9
2013-11-01protein level
3 19 7
2013-09-12protein level
3 19 7
2013-08-17protein level
3 19 7
2013-07-15protein level
3 14 6
2013-06-11protein level
3 14 6
2013-02-12protein level
1 11 5
2012-12-20protein level
1 11 5
2012-10-30protein level
1 15 5
2012-10-07protein level
1 15 5
2012-08-24protein level
1 15 5
2012-07-28protein level
1 14 5
2012-06-08protein level
1 15 5
2012-05-07protein level
1 15 5
2012-04-10protein level
1 15 5
2012-01-13protein level
1 10 5
2011-12-20protein level
1 9 5
2011-11-11protein level
1 9 5
2011-08-23protein level
1 9 5
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P78417-1
0 12 0 27547.9611
NX_P78417-2
0 10 0 23692.9877
NX_P78417-3
0 11 0 24779.5775
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-712083,EBI-352682 HSPB1  
  .positive regulation of endothelial cell chemotaxis
.negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
.platelet aggregation
  + 17 more...
.poly(A) RNA binding
.ubiquitin binding
.identical protein binding
  + 3 more...
.extracellular exosome
.Z disc
.focal adhesion
  + 8 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue155
adrenal gland60
ascites125
bladder33
blood49
bone111
brain43
cervix41
connective tissue134
embryonic tissue61
esophagus99
eye47
heart212
intestine99
kidney61
liver116
lung176
lymph112
lymph node11
mammary gland92
mouth226
muscle47
ovary118
pancreas135
parathyroid679
pharynx24
pituitary gland181
placenta63
prostate94
salivary gland345
skin332
spleen74
stomach62
testis22
thymus50
thyroid21
tonsil58
trachea19
umbilical cord726
uterus90
vascular96
Health State
TissuesTPM*
normal83
bladder carcinoma113
breast (mammary gland) tumor118
cervical tumor28
chondrosarcoma181
colorectal tumor71
esophageal tumor115
gastrointestinal tumor92
germ cell tumor45
glioma121
head and neck tumor149
kidney tumor58
leukemia74
liver tumor135
lung tumor145
lymphoma83
non-neoplasia62
ovarian tumor118
pancreatic tumor76
primitive neuroectodermal tumor of the CNS39
prostate cancer96
retinoblastoma64
skin tumor327
soft tissue/muscle tissue tumor183
uterine tumor44
Developmental Stage
TissuesTPM*
adult99
embryoid body114
blastocyst16
neonate354
fetus107
juvenile53
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue49.2
adrenal gland86.4
appendix78.6
bone marrow91
cerebral cortex57
colon68.2
duodenum118.4
esophagus47.5
gallbladder69.2
heart muscle159.5
kidney97.5
liver242
lung72.5
lymph node65.2
ovary59.7
pancreas28.3
placenta82.8
prostate48.4
salivary gland42.6
skin24.5
small intestine116.9
spleen61.9
stomach59.6
testis14.7
thyroid gland60.2
urinary bladder69.4
Tissues
TissuesExpression level
adrenal glandMedium
cerebral cortexLow
kidneyMedium
lateral ventricleMedium
liverHigh
lungMedium
placentaLow
seminal vesicleLow
skin 1Medium
soft tissue 1Medium
soft tissue 2Low
testisLow
thyroid glandMedium
tonsilLow
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*605482, gene) Glutathione s-transferase, omega-1; GSTO1OMIM


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