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> Protein (NX_P80404)
Protein (NX_P80404)
Protein
Gene SymbolABAT to neXtProt (NX_P80404)
Description4-aminobutyrate aminotransferase, mitochondrial
Chromosome16
Location16p13.2 (8768422 ~ 8878432) to Ensembl
Sequene Features : Isoforms 1, Variants 60, PTMs 12 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.behavioral response to cocaine
.negative regulation of blood pressure
.response to ethanol
  + 10 more...
.iron-sulfur cluster binding
.(S)-3-amino-2-methylpropionate transaminase activity
.metal ion binding
  + 4 more...
.extracellular exosome
.neuron projection
.4-aminobutyrate transaminase complex
  + 2 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 60 12
2014-09-19protein level
1 43 12
2014-05-27protein level
1 43 12
2014-02-25protein level
1 44 9
2013-12-09protein level
1 37 9
2013-11-01protein level
1 36 9
2013-09-12protein level
1 36 4
2013-08-17protein level
1 36 4
2013-07-15protein level
1 26 4
2013-06-11protein level
1 26 4
2013-02-12protein level
1 13 4
2012-12-20protein level
1 15 4
2012-10-30protein level
1 16 4
2012-10-07protein level
1 16 4
2012-08-24protein level
1 15 4
2012-07-28protein level
1 15 4
2012-06-08protein level
1 28 4
2012-05-07protein level
1 23 4
2012-04-10protein level
1 23 4
2012-01-13protein level
1 20 4
2011-12-20protein level
1 20 4
2011-11-11protein level
1 20 4
2011-08-23protein level
1 20 4
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P80404-1
29 0 0 56402.4274
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland91
blood16
bone55
brain118
connective tissue26
embryonic tissue42
esophagus49
eye47
heart11
intestine8
kidney85
liver228
lung20
lymph45
lymph node55
mammary gland46
mouth15
muscle18
pancreas135
parathyroid97
pituitary gland242
placenta17
prostate58
skin9
stomach10
testis27
thyroid85
uterus8
vascular19
Health State
TissuesTPM*
normal82
adrenal tumor237
breast (mammary gland) tumor42
chondrosarcoma24
colorectal tumor8
esophageal tumor57
gastrointestinal tumor8
germ cell tumor37
glioma93
head and neck tumor14
kidney tumor43
leukemia42
liver tumor177
lymphoma41
non-neoplasia10
pancreatic tumor95
primitive neuroectodermal tumor of the CNS7
prostate cancer115
soft tissue/muscle tissue tumor31
uterine tumor11
Developmental Stage
TissuesTPM*
adult65
embryoid body42
fetus105
infant42
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue2.6
adrenal gland28.4
appendix4.9
bone marrow2
cerebral cortex98.7
colon9.2
duodenum35.7
esophagus5.8
gallbladder4.7
heart muscle11
kidney105.7
liver180.7
lung4
lymph node5.5
ovary9.9
pancreas62.9
placenta4.5
prostate23.9
salivary gland3.2
skin2.6
small intestine17.5
spleen4.2
stomach6.8
testis17.5
thyroid gland24.8
urinary bladder15.6
Tissues
TissuesExpression level
adrenal glandMedium
appendixMedium
breastLow
bronchusMedium
cerebellumHigh
cerebral cortexMedium
colonMedium
duodenumHigh
endometrium 1Medium
endometrium 2Low
epididymisLow
esophagusLow
fallopian tubeLow
gallbladderHigh
hippocampusMedium
kidneyHigh
lateral ventricleHigh
liverHigh
lymph nodeLow
nasopharynxMedium
pancreasHigh
parathyroid glandMedium
placentaLow
prostateHigh
rectumMedium
salivary glandLow
seminal vesicleMedium
small intestineMedium
soft tissue 1Low
soft tissue 2Low
spleenLow
stomach 1Medium
stomach 2Medium
testisMedium
thyroid glandHigh
tonsilLow
urinary bladderMedium
vaginaLow
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*137150, gene) 4-@aminobutyrate aminotransferase; ABATOMIM
2(#613163, phenotype) Gaba-transaminase deficiencyOMIM


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