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> Protein (NX_P83876)
Protein (NX_P83876)
Protein
Gene SymbolTXNL4A to neXtProt (NX_P83876)
DescriptionThioredoxin-like protein 4A
Chromosome18
Location18q23 (77732867 ~ 77793949) to Ensembl
Sequene Features : Isoforms 1, Variants 7, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.cell division
.gene expression
.RNA splicing
  + 4 more...
.N/A .U4/U6 x U5 tri-snRNP complex
.U5 snRNP
.spliceosomal complex
.nucleoplasm
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 7 4
2014-09-19protein level
1 5 4
2014-05-27protein level
1 5 4
2014-02-25protein level
1 5 4
2013-12-09protein level
1 5 4
2013-11-01protein level
1 4 2
2013-09-12protein level
1 4 2
2013-08-17protein level
1 4 2
2013-07-15protein level
1 6 2
2013-06-11protein level
1 6 2
2013-02-12protein level
1 0 2
2012-12-20protein level
1 0 2
2012-10-30protein level
1 0 2
2012-10-07protein level
1 0 2
2012-08-24protein level
1 0 2
2012-07-28protein level
1 0 2
2012-06-08protein level
1 1 2
2012-05-07protein level
1 2 2
2012-04-10protein level
1 2 2
2012-01-13protein level
1 2 2
2011-12-20protein level
1 2 2
2011-11-11protein level
1 2 2
2011-08-23protein level
1 2 2
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P83876-1
8 0 0 16775.2011
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-746539,EBI-768015 CD2BP2  
  .negative regulation of phosphatase activity
.gene expression
.RNA splicing
  + 2 more...
.ribonucleoprotein complex binding .cytoplasm
.U5 snRNP
.nucleoplasm
.nucleus
2 EBI-746539,EBI-741037 LZTS2  
  .negative regulation of protein localization to nucleus
.negative regulation of canonical Wnt signaling pathway
.spindle midzone assembly
  + 7 more...
.N/A .midbody
.microtubule
.centrosome
.cytoplasm
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
adrenal gland60
ascites75
bladder33
blood32
bone27
brain38
cervix20
connective tissue107
embryonic tissue32
eye71
heart44
intestine34
kidney14
liver14
lung68
lymph158
lymph node22
mammary gland19
mouth15
muscle37
ovary39
pancreas121
pharynx319
placenta17
prostate52
salivary gland49
skin61
stomach41
testis27
thyroid42
tonsil176
umbilical cord145
uterus68
Health State
TissuesTPM*
normal37
breast (mammary gland) tumor10
cervical tumor28
chondrosarcoma48
colorectal tumor17
gastrointestinal tumor33
germ cell tumor26
glioma83
head and neck tumor119
kidney tumor14
leukemia10
liver tumor20
lung tumor136
lymphoma96
non-neoplasia10
ovarian tumor26
pancreatic tumor47
primitive neuroectodermal tumor of the CNS39
prostate cancer57
retinoblastoma64
skin tumor79
soft tissue/muscle tissue tumor135
uterine tumor77
Developmental Stage
TissuesTPM*
adult60
embryoid body28
blastocyst16
neonate64
fetus23
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue37.2
adrenal gland50.6
appendix42.3
bone marrow39
cerebral cortex47.7
colon42.9
duodenum32.9
esophagus37.3
gallbladder29.3
heart muscle44.9
kidney44.2
liver23.4
lung29.6
lymph node54.7
ovary14
pancreas32.2
placenta31.7
prostate36.1
salivary gland42.2
skin33.2
small intestine34.7
spleen33
stomach37.1
testis54
thyroid gland37.3
urinary bladder41.5
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Disease
No.Disease DescriptionRef.
1(%608572, phenotype) Burn-mckeown syndromeOMIM
2(*611595, gene) Thioredoxin-like 4a; TXNL4AOMIM


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