Home| Contact Us

HOME SEARCH STATISTICS
> Protein (NX_P98172)
Protein (NX_P98172)
Protein
Gene SymbolEFNB1 to neXtProt (NX_P98172)
DescriptionEphrin-B1
ChromosomeX
LocationXq13.1 (68048840 ~ 68061990) to Ensembl
Sequene Features : Isoforms 1, Variants 50, PTMs 14 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.ephrin receptor signaling pathway
.positive regulation of T cell proliferation
.embryonic pattern specification
  + 4 more...
.ephrin receptor binding .extracellular exosome
.synapse
.membrane raft
  + 4 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 50 14
2014-09-19protein level
1 46 14
2014-05-27protein level
1 46 14
2014-02-25protein level
1 45 14
2013-12-09protein level
1 44 15
2013-11-01protein level
1 44 15
2013-09-12protein level
1 44 15
2013-08-17protein level
1 44 14
2013-07-15protein level
1 39 6
2013-06-11protein level
1 39 6
2013-02-12protein level
1 27 6
2012-12-20protein level
1 27 6
2012-10-30protein level
1 27 6
2012-10-07protein level
1 27 6
2012-08-24protein level
1 27 6
2012-07-28protein level
1 27 6
2012-06-08protein level
1 25 6
2012-05-07protein level
1 25 6
2012-04-10protein level
1 25 6
2012-01-13protein level
1 23 6
2011-12-20protein level
1 23 6
2011-11-11protein level
1 23 6
2011-08-23protein level
1 23 6
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P98172-1
15 0 1 37982.3824
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-538287,EBI-641062 ERBB2  
  .regulation of ERK1 and ERK2 cascade
.positive regulation of epithelial cell proliferation
.oligodendrocyte differentiation
  + 35 more...
.protein dimerization activity
.protein heterodimerization activity
.ErbB-3 class receptor binding
  + 9 more...
.perinuclear region of cytoplasm
.receptor complex
.cytoplasmic vesicle
  + 7 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
ascites301
bladder33
bone27
brain19
connective tissue33
embryonic tissue126
esophagus198
eye52
heart89
intestine142
kidney90
larynx42
liver4
lung53
mouth75
muscle28
ovary108
pancreas42
placenta63
prostate63
skin33
spleen37
stomach10
testis6
thyroid21
uterus47
vascular77
Health State
TissuesTPM*
normal42
adrenal tumor79
chondrosarcoma48
colorectal tumor79
esophageal tumor231
gastrointestinal tumor118
germ cell tumor45
glioma83
head and neck tumor52
kidney tumor188
leukemia10
lung tumor19
non-neoplasia51
ovarian tumor65
pancreatic tumor85
primitive neuroectodermal tumor of the CNS31
prostate cancer9
retinoblastoma21
skin tumor39
soft tissue/muscle tissue tumor15
uterine tumor55
Developmental Stage
TissuesTPM*
adult47
embryoid body242
blastocyst65
fetus70
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue28.2
adrenal gland11
appendix7.5
bone marrow1.5
cerebral cortex3.2
colon19.5
duodenum14.8
esophagus10.5
gallbladder19.1
heart muscle9.6
kidney18.8
liver3.5
lung18.2
lymph node4.1
ovary7.2
pancreas1.8
placenta23
prostate9.7
salivary gland6.5
skin21.6
small intestine14.8
spleen15.9
stomach16.9
testis6.3
thyroid gland5.1
urinary bladder15.4
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*300035, gene) Ephrin b1; EFNB1OMIM
2(#304110, phenotype) Craniofrontonasal syndrome; CFNSOMIM


#424, YPRC/BPRC, Industry-University Research Center, Yonsei Univ., Seodaemun-gu, Seoul, Korea, 120-749
Tel: +82-2-2123-6626, Fax: +82-2-393-6589
2014-2019 (C) Yonsei Proteome Research Center