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> Protein (NX_Q00013)
Protein (NX_Q00013)
Protein
Gene SymbolMPP1 to neXtProt (NX_Q00013)
Description55 kDa erythrocyte membrane protein
ChromosomeX
LocationXq28 (154006959 ~ 154049282) to Ensembl
Sequene Features : Isoforms 3, Variants 65, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.regulation of neutrophil chemotaxis
.nucleotide phosphorylation
.signal transduction
.guanylate kinase activity .stereocilium
.cortical cytoskeleton
.membrane
  + 2 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
3 65 8
2014-09-19protein level
3 51 8
2014-05-27protein level
3 51 8
2014-02-25protein level
3 49 8
2013-12-09protein level
3 45 8
2013-11-01protein level
3 45 8
2013-09-12protein level
3 45 9
2013-08-17protein level
3 45 9
2013-07-15protein level
3 28 6
2013-06-11protein level
3 28 6
2013-02-12protein level
3 13 14
2012-12-20protein level
3 13 14
2012-10-30protein level
2 14 9
2012-10-07protein level
2 14 5
2012-08-24protein level
2 10 5
2012-07-28protein level
2 10 5
2012-06-08protein level
2 10 5
2012-05-07protein level
2 10 5
2012-04-10protein level
2 10 5
2012-01-13protein level
1 3 5
2011-12-20protein level
1 3 5
2011-11-11protein level
1 3 4
2011-08-23protein level
1 3 4
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q00013-1
0 23 0 52263.4978
NX_Q00013-2
1 21 0 49043.8403
NX_Q00013-3
1 21 0 49822.335
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-711788,EBI-740929 KLHL12  
  .negative regulation of canonical Wnt signaling pathway
.COPII vesicle coating
.Wnt signaling pathway
  + 2 more...
.N/A .Cul3-RING ubiquitin ligase complex
.ER to Golgi transport vesicle
.cytosol
.Golgi membrane
2 EBI-711788,EBI-748974 OPTN  
  .Golgi ribbon formation
.defense response to Gram-negative bacterium
.negative regulation of I-kappaB kinase/NF-kappaB signaling
  + 10 more...
.K63-linked polyubiquitin binding
.identical protein binding
.polyubiquitin binding
  + 2 more...
.recycling endosome
.perinuclear region of cytoplasm
.cytoplasmic membrane-bounded vesicle
  + 8 more...
3 EBI-711788,EBI-748356 DNPEP  
  .peptide metabolic process .zinc ion binding
.metallopeptidase activity
.aminopeptidase activity
.blood microparticle
.cytoplasm
.nucleoplasm
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
adrenal gland91
bladder100
blood261
bone41
bone marrow246
brain68
cervix20
connective tissue120
embryonic tissue28
eye23
heart55
intestine21
kidney175
liver82
lung89
lymph node11
mammary gland46
mouth15
ovary39
pancreas23
placenta222
prostate26
salivary gland49
skin23
spleen262
stomach62
testis32
thymus388
thyroid150
uterus34
vascular19
Health State
TissuesTPM*
normal97
adrenal tumor158
breast (mammary gland) tumor53
chondrosarcoma48
colorectal tumor17
gastrointestinal tumor25
germ cell tumor45
glioma18
head and neck tumor44
kidney tumor87
leukemia232
liver tumor41
lung tumor116
non-neoplasia186
ovarian tumor26
pancreatic tumor47
primitive neuroectodermal tumor of the CNS62
prostate cancer9
retinoblastoma64
skin tumor31
soft tissue/muscle tissue tumor23
uterine tumor11
Developmental Stage
TissuesTPM*
adult74
embryoid body14
blastocyst16
neonate193
fetus111
infant85
juvenile53
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue28
adrenal gland33.3
appendix39.1
bone marrow111.5
cerebral cortex28
colon19.1
duodenum66.1
esophagus11.7
gallbladder36.9
heart muscle22.7
kidney40.3
liver25.1
lung25.5
lymph node29
ovary13.1
pancreas17.3
placenta90.4
prostate19.6
salivary gland22.2
skin11.2
small intestine58.8
spleen37.8
stomach11.7
testis12.5
thyroid gland18.4
urinary bladder20.2
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*305360, gene) Membrane protein, palmitoylated 1; MPP1OMIM


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