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> Protein (NX_Q00987)
Protein (NX_Q00987)
Protein
Gene SymbolMDM2 to neXtProt (NX_Q00987)
DescriptionE3 ubiquitin-protein ligase Mdm2
Chromosome12
Location12q15 (69201956 ~ 69239214) to Ensembl
Sequene Features : Isoforms 11, Variants 62, PTMs 13 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.negative regulation of signal transduction by p53 class mediator
.cellular response to UV-C
.cellular response to hypoxia
  + 44 more...
.ubiquitin protein ligase activity
.identical protein binding
.ubiquitin protein ligase binding
  + 5 more...
.synapse
.protein complex
.endocytic vesicle membrane
  + 6 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
11 62 13
2014-09-19protein level
11 48 13
2014-05-27protein level
11 48 13
2014-02-25protein level
11 47 13
2013-12-09protein level
11 38 13
2013-11-01protein level
11 37 12
2013-09-12protein level
11 37 12
2013-08-17protein level
11 37 12
2013-07-15protein level
11 21 12
2013-06-11protein level
11 21 12
2013-02-12protein level
11 7 44
2012-12-20protein level
11 8 44
2012-10-30protein level
11 9 4
2012-10-07protein level
11 9 1
2012-08-24protein level
11 7 1
2012-07-28protein level
11 7 1
2012-06-08protein level
11 15 1
2012-05-07protein level
11 15 1
2012-04-10protein level
11 15 1
2012-01-13protein level
11 15 1
2011-12-20protein level
11 16 1
2011-11-11protein level
11 16 1
2011-08-23protein level
11 16 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q00987-1
0 19 0 55197.9749
NX_Q00987-10
1 15 0 49217.148
NX_Q00987-11
1 18 0 55955.3742
NX_Q00987-2
1 10 0 33118.9907
NX_Q00987-3
1 10 0 30245.7214
NX_Q00987-4
1 10 0 24451.3838
NX_Q00987-5
1 11 0 35956.6386
NX_Q00987-6
2 5 0 14679.02
NX_Q00987-7
2 2 0 11578.9793
NX_Q00987-8
0 17 0 48457.4958
NX_Q00987-9
0 17 0 49867.2848
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-389668,EBI-398437 MDM4  
  .cellular response to hypoxia
.negative regulation of cell cycle arrest
.protein stabilization
  + 9 more...
.enzyme binding
.zinc ion binding
.nucleoplasm
.nucleus
2 EBI-389668,EBI-1551512 PPM1D  
  .peptidyl-threonine dephosphorylation
.response to bacterium
.response to radiation
  + 3 more...
.metal ion binding
.protein serine/threonine phosphatase activity
.nucleus
3 EBI-389668,EBI-743272 USP2  
  .regulation of proteasomal protein catabolic process
.protein stabilization
.positive regulation of skeletal muscle tissue development
  + 11 more...
.metal ion binding
.ubiquitin protein ligase binding
.cyclin binding
  + 2 more...
.perinuclear region of cytoplasm
.cell cortex
.centrosome
  + 2 more...
4 EBI-389668,EBI-78473 ESR1  
  .cellular response to estradiol stimulus
.epithelial cell proliferation involved in mammary gland duct elongation
.mammary gland alveolus development
  + 33 more...
.ATPase binding
.identical protein binding
.estrogen-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
  + 14 more...
.transcriptionally active chromatin
.integral component of membrane
.membrane
  + 5 more...
5 EBI-389668,EBI-458391 S100B  
  .negative regulation of skeletal muscle cell differentiation
.cellular response to hypoxia
.long-term synaptic potentiation
  + 14 more...
.RAGE receptor binding
.calcium-dependent protein binding
.tau protein binding
  + 5 more...
.perinuclear region of cytoplasm
.intracellular membrane-bounded organelle
.neuronal cell body
  + 5 more...
6 EBI-389668,EBI-366083 TP53  
  .positive regulation of intrinsic apoptotic signaling pathway
.positive regulation of reactive oxygen species metabolic process
.negative regulation of reactive oxygen species metabolic process
  + 99 more...
.protein phosphatase 2A binding
.chaperone binding
.protein N-terminus binding
  + 27 more...
.protein complex
.PML body
.nuclear matrix
  + 11 more...
7 EBI-389668,EBI-852823 JUN  
  .positive regulation of DNA-templated transcription, initiation
.negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
.cellular response to calcium ion
  + 60 more...
.R-SMAD binding
.poly(A) RNA binding
.transcription regulatory region DNA binding
  + 15 more...
.transcriptional repressor complex
.cytosol
.nuclear euchromatin
  + 4 more...
8 EBI-389668,EBI-491274 RB1  
  .negative regulation of G1/S transition of mitotic cell cycle
.hepatocyte apoptotic process
.regulation of centromere complex assembly
  + 39 more...
.phosphoprotein binding
.androgen receptor binding
.identical protein binding
  + 7 more...
.Rb-E2F complex
.PML body
.SWI/SNF complex
  + 4 more...
9 EBI-389668,EBI-352877 S100A6  
  .positive regulation of fibroblast proliferation
.axonogenesis
.signal transduction
.calcium-dependent protein binding
.S100 protein binding
.protein homodimerization activity
  + 4 more...
.extracellular exosome
.perinuclear region of cytoplasm
.extrinsic component of cytoplasmic side of plasma membrane
  + 5 more...
10 EBI-389668,EBI-78579 NPM1  
  .regulation of eIF2 alpha phosphorylation by dsRNA
.regulation of endoribonuclease activity
.protein oligomerization
  + 20 more...
.unfolded protein binding
.NF-kappaB binding
.protein heterodimerization activity
  + 10 more...
.spindle pole centrosome
.ribonucleoprotein complex
.membrane
  + 7 more...
11 EBI-389668,EBI-475981 IGF1R  
  .positive regulation of steroid hormone biosynthetic process
.prostate gland epithelium morphogenesis
.negative regulation of protein kinase B signaling
  + 30 more...
.insulin receptor substrate binding
.insulin binding
.phosphatidylinositol 3-kinase binding
  + 7 more...
.receptor complex
.intracellular membrane-bounded organelle
.neuron projection
  + 4 more...
12 EBI-389668,EBI-3390054 UBC  
  .programmed necrotic cell death
.apoptotic signaling pathway
.energy homeostasis
  + 90 more...
.poly(A) RNA binding
.protease binding
.extracellular exosome
.endocytic vesicle membrane
.endosome membrane
  + 3 more...
13 EBI-389668,EBI-608057 AR  
  .negative regulation of extrinsic apoptotic signaling pathway
.regulation of establishment of protein localization to plasma membrane
.protein oligomerization
  + 21 more...
.ATPase binding
.protein dimerization activity
.transcription regulatory region DNA binding
  + 14 more...
.protein complex
.cytosol
.cytoplasm
  + 3 more...
14 EBI-389668,EBI-1056902 EZR  
  .establishment of endothelial barrier
.actin filament bundle assembly
.positive regulation of protein secretion
  + 13 more...
.actin filament binding
.cell adhesion molecule binding
.poly(A) RNA binding
.cytoplasmic side of apical plasma membrane
.Schwann cell microvillus
.astrocyte projection
  + 30 more...
15 EBI-389668,EBI-2682803 JUND  
  .cellular response to calcium ion
.regulation of cell cycle
.response to cAMP
  + 18 more...
.transcription regulatory region DNA binding
.enzyme binding
.transcription factor binding
  + 4 more...
.transcription factor complex
.nucleoplasm
.nucleus
  + 2 more...
16 EBI-389668,EBI-346967 NCL  
  .positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter
.angiogenesis
.poly(A) RNA binding
.identical protein binding
.telomeric DNA binding
  + 3 more...
.extracellular exosome
.cytoplasmic ribonucleoprotein granule
.ribonucleoprotein complex
  + 5 more...
17 EBI-389668,EBI-743686 S100A1  
  .positive regulation of voltage-gated calcium channel activity
.intracellular signal transduction
.substantia nigra development
  + 2 more...
.ATPase binding
.S100 protein binding
.protein homodimerization activity
  + 2 more...
.protein complex
.neuron projection
.M band
  + 3 more...
18 EBI-389668,EBI-351193 RPS3  
  .positive regulation of apoptotic signaling pathway
.positive regulation of DNA N-glycosylase activity
.cell division
  + 20 more...
.iron-sulfur cluster binding
.NF-kappaB binding
.protein kinase A binding
  + 8 more...
.extracellular exosome
.ruffle membrane
.ribonucleoprotein complex
  + 9 more...
19 EBI-389668,EBI-3904795 ADRBK1  
  .cardiac muscle contraction
.neurotrophin TRK receptor signaling pathway
.viral entry into host cell
  + 17 more...
.beta-adrenergic receptor kinase activity
.Edg-2 lysophosphatidic acid receptor binding
.alpha-2A adrenergic receptor binding
  + 3 more...
.primary cilium
.membrane
.plasma membrane
  + 2 more...
20 EBI-389668,EBI-348380 PSMA3  
  .positive regulation of canonical Wnt signaling pathway
.negative regulation of canonical Wnt signaling pathway
.regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
  + 23 more...
.threonine-type endopeptidase activity
.endopeptidase activity
.extracellular exosome
.proteasome core complex, alpha-subunit complex
.proteasome core complex
  + 5 more...
21 EBI-389668,EBI-717058 S100A4  
  .positive regulation of I-kappaB kinase/NF-kappaB signaling
.epithelial to mesenchymal transition
.RAGE receptor binding
.poly(A) RNA binding
.calcium ion binding
.extracellular exosome
.perinuclear region of cytoplasm
.neuron projection
  + 2 more...
22 EBI-389668,EBI-752230 S100A2  
  .endothelial cell migration .identical protein binding
.calcium ion binding
.N/A
23 EBI-389668,EBI-295890 PML  
  .positive regulation of extrinsic apoptotic signaling pathway
.regulation of double-strand break repair
.negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
  + 57 more...
.cobalt ion binding
.protein heterodimerization activity
.protein homodimerization activity
  + 5 more...
.extrinsic component of endoplasmic reticulum membrane
.nuclear membrane
.early endosome membrane
  + 7 more...
24 EBI-389668,EBI-296087 AKT1  
  .negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
.response to insulin-like growth factor stimulus
.negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
  + 108 more...
.14-3-3 protein binding
.phosphatidylinositol-3,4-bisphosphate binding
.identical protein binding
  + 8 more...
.ciliary basal body
.microtubule cytoskeleton
.cell-cell junction
  + 7 more...
25 EBI-389668,EBI-524064 CASP3  
  .regulation of apoptotic DNA fragmentation
.execution phase of apoptosis
.intrinsic apoptotic signaling pathway
  + 37 more...
.cysteine-type endopeptidase activity involved in execution phase of apoptosis
.cysteine-type endopeptidase activity involved in apoptotic process
.peptidase activity
  + 3 more...
.plasma membrane
.cytosol
.nucleoplasm
.nucleus
26 EBI-389668,EBI-356336 RPS27  
  .cellular protein metabolic process
.viral transcription
.viral life cycle
  + 11 more...
.poly(A) RNA binding
.zinc ion binding
.structural constituent of ribosome
.DNA binding
.cytosolic small ribosomal subunit
.ribosome
.cytosol
.nucleus
27 EBI-389668,EBI-358018 RPL5  
  .cellular protein metabolic process
.ribosomal large subunit biogenesis
.viral transcription
  + 10 more...
.poly(A) RNA binding
.5S rRNA binding
.structural constituent of ribosome
.RNA binding
.extracellular exosome
.ribonucleoprotein complex
.cytosolic large ribosomal subunit
  + 6 more...
28 EBI-389668,EBI-1383726 CSNK1A1  
  .positive regulation of canonical Wnt signaling pathway
.cell division
.peptidyl-serine phosphorylation
  + 7 more...
.ATP binding
.protein serine/threonine kinase activity
.protein kinase activity
.primary cilium
.nuclear speck
.membrane
  + 4 more...
29 EBI-389668,EBI-751621 CSNK1D  
  .positive regulation of canonical Wnt signaling pathway
.spindle assembly
.regulation of circadian rhythm
  + 13 more...
.tau-protein kinase activity
.peptide binding
.ATP binding
  + 2 more...
.perinuclear region of cytoplasm
.plasma membrane
.spindle microtubule
  + 5 more...
30 EBI-389668,EBI-749343 CSNK1E  
  .positive regulation of canonical Wnt signaling pathway
.regulation of circadian rhythm
.cellular protein localization
  + 14 more...
.poly(A) RNA binding
.ATP binding
.protein serine/threonine kinase activity
.protein kinase activity
.ribonucleoprotein complex
.cytosol
.cytoplasm
.nucleus
31 EBI-389668,EBI-476768 PLK1  
  .regulation of mitotic spindle assembly
.protein localization to chromatin
.regulation of cell cycle
  + 36 more...
.protein kinase binding
.kinase activity
.anaphase-promoting complex binding
  + 4 more...
.spindle midzone
.midbody
.microtubule cytoskeleton
  + 10 more...
32 EBI-389668,EBI-355546 PSME3  
  .negative regulation of extrinsic apoptotic signaling pathway
.positive regulation of canonical Wnt signaling pathway
.negative regulation of canonical Wnt signaling pathway
  + 24 more...
.MDM2/MDM4 family protein binding
.endopeptidase activator activity
.identical protein binding
.p53 binding
.membrane
.proteasome activator complex
.cytosol
  + 4 more...
33 EBI-389668,EBI-304185 HNRNPK  
  .regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter
.positive regulation of receptor-mediated endocytosis
.positive regulation of transcription from RNA polymerase II promoter
  + 8 more...
.poly(A) RNA binding
.RNA binding
.single-stranded DNA binding
  + 2 more...
.catalytic step 2 spliceosome
.extracellular exosome
.cell projection
  + 7 more...
34 EBI-389668,EBI-354360 RPS7  
  .cellular protein metabolic process
.ribosomal small subunit biogenesis
.viral transcription
  + 11 more...
.poly(A) RNA binding
.structural constituent of ribosome
.RNA binding
.extracellular exosome
.small-subunit processome
.90S preribosome
  + 10 more...
35 EBI-389668,EBI-353303 RPL23  
  .cellular protein metabolic process
.viral transcription
.viral life cycle
  + 9 more...
.poly(A) RNA binding
.structural constituent of ribosome
.extracellular exosome
.cytosolic large ribosomal subunit
.membrane
  + 5 more...
36 EBI-389668,EBI-354380 RPL11  
  .cellular protein metabolic process
.ribosomal large subunit biogenesis
.protein localization to nucleus
  + 12 more...
.poly(A) RNA binding
.rRNA binding
.structural constituent of ribosome
.RNA binding
.extracellular exosome
.cytosolic large ribosomal subunit
.membrane
  + 3 more...
37 EBI-389668,EBI-352162 EEF1A1  
  .cellular response to epidermal growth factor stimulus
.cellular protein metabolic process
.gene expression
  + 4 more...
.poly(A) RNA binding
.protein kinase binding
.GTP binding
  + 3 more...
.extracellular exosome
.ruffle membrane
.cortical actin cytoskeleton
  + 7 more...
38 EBI-389668,EBI-80389 DLG4  
  .regulation of grooming behavior
.positive regulation of excitatory postsynaptic membrane potential
.regulation of N-methyl-D-aspartate selective glutamate receptor activity
  + 22 more...
.scaffold protein binding
.neuroligin family protein binding
.ionotropic glutamate receptor binding
  + 10 more...
.neuronal postsynaptic density
.excitatory synapse
.postsynaptic membrane
  + 17 more...
39 EBI-389668,EBI-1044081 FKBP3  
  .chaperone-mediated protein folding
.protein peptidyl-prolyl isomerization
.poly(A) RNA binding
.FK506 binding
.receptor activity
.peptidyl-prolyl cis-trans isomerase activity
.endoplasmic reticulum membrane
.nucleus
40 EBI-389668,EBI-1053182 SET  
  .negative regulation of transcription, DNA-templated
.negative regulation of neuron apoptotic process
.negative regulation of catalytic activity
  + 9 more...
.histone binding
.protein phosphatase type 2A regulator activity
.protein phosphatase inhibitor activity
.DNA binding
.perinuclear region of cytoplasm
.protein complex
.cytosol
  + 4 more...
41 EBI-389668,EBI-1266156 PPP2R5C  
  .proteasome-mediated ubiquitin-dependent protein catabolic process
.intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
.regulation of protein phosphatase type 2A activity
  + 3 more...
.protein phosphatase type 2A regulator activity .nucleus
.chromosome, centromeric region
.protein phosphatase type 2A complex
42 EBI-389668,EBI-359390 CUL1  
  .intrinsic apoptotic signaling pathway
.regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
.positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
  + 17 more...
.N/A .Parkin-FBXW7-Cul1 ubiquitin ligase complex
.cullin-RING ubiquitin ligase complex
.SCF ubiquitin ligase complex
  + 2 more...
43 EBI-389668,EBI-3910729 NR0B2  
  .negative regulation of sequence-specific DNA binding transcription factor activity
.positive regulation of insulin secretion
.organ regeneration
  + 7 more...
.protein homodimerization activity
.protein domain specific binding
.transcription corepressor activity
  + 3 more...
.protein complex
.cytoplasm
.nucleoplasm
.nucleus
44 EBI-389668,EBI-3917143 GORAB  
  .N/A .N/A .Golgi apparatus
.cytoplasm
.nucleolus
  + 2 more...
45 EBI-389668,EBI-355126 RPS27L  
  .positive regulation of translation
.intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
.mitotic G1 DNA damage checkpoint
  + 4 more...
.metal ion binding
.poly(A) RNA binding
.cysteine-type endopeptidase activator activity involved in apoptotic process
  + 2 more...
.ribosome
.nucleus
46 EBI-389668,EBI-752324 RYBP  
  .histone H2A monoubiquitination
.multicellular organismal development
.apoptotic process
  + 2 more...
.zinc ion binding
.transcription corepressor activity
.DNA binding
.cytoplasm
.nucleoplasm
47 EBI-389668,EBI-625922 CDKN2A  
  .negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
.regulation of protein targeting to mitochondrion
.negative regulation of proteolysis involved in cellular protein catabolic process
  + 33 more...
.MDM2/MDM4 family protein binding
.ubiquitin-protein transferase inhibitor activity
.transcription factor binding
  + 2 more...
.protein complex
.mitochondrion
.nucleolus
  + 2 more...
48 EBI-389668,EBI-866435 JMY  
  .intrinsic apoptotic signaling pathway by p53 class mediator
.actin polymerization-dependent cell motility
.'de novo' actin filament nucleation
  + 6 more...
.transcription coactivator activity .cell leading edge
.cell junction
.plasma membrane
  + 4 more...
49 EBI-389668,EBI-1170425 RYR2  
  .positive regulation of calcium-transporting ATPase activity
.regulation of ventricular cardiac muscle cell action potential
.regulation of atrial cardiac muscle cell action potential
  + 40 more...
.calcium-induced calcium release activity
.ion channel binding
.suramin binding
  + 10 more...
.extracellular exosome
.protein complex
.calcium channel complex
  + 7 more...
50 EBI-389668,EBI-302474 USP7  
  .regulation of proteasomal protein catabolic process
.regulation of sequence-specific DNA binding transcription factor activity
.proteasome-mediated ubiquitin-dependent protein catabolic process
  + 7 more...
.ubiquitin protein ligase binding
.transcription factor binding
.protein C-terminus binding
  + 3 more...
.PML body
.nuclear body
.cytosol
.nucleus
51 EBI-389668,EBI-1058491 OTUB1  
  .negative regulation of double-strand break repair
.negative regulation of histone H2A K63-linked ubiquitination
.protein K48-linked deubiquitination
  + 3 more...
.ubiquitin binding
.ubiquitin protein ligase binding
.NEDD8-specific protease activity
.ubiquitin-specific protease activity
.extracellular exosome
.cytoplasm
52 EBI-389668,EBI-641642 GNL3  
  .positive regulation of pri-miRNA transcription from RNA polymerase II promoter
.ribosome biogenesis
.regulation of cell proliferation
  + 2 more...
.poly(A) RNA binding
.GTP binding
.GTPase activity
.membrane
.nucleolus
.nucleoplasm
  + 2 more...
53 EBI-389668,EBI-367363 RASSF1  
  .negative regulation of cell cycle arrest
.protein stabilization
.positive regulation of protein ubiquitination
  + 3 more...
.protein N-terminus binding
.identical protein binding
.zinc ion binding
.microtubule cytoskeleton
.plasma membrane
.microtubule
  + 4 more...
54 EBI-389668,EBI-746682 GNL3L  
  .ribosome biogenesis
.metabolic process
.poly(A) RNA binding
.GTP binding
.GTPase activity
.membrane
.mitochondrion
.cytoplasm
  + 3 more...
55 EBI-389668,EBI-77321 DAXX  
  .positive regulation of apoptotic signaling pathway
.positive regulation of neuron death
.negative regulation of transcription, DNA-templated
  + 13 more...
.androgen receptor binding
.protein N-terminus binding
.protein homodimerization activity
  + 10 more...
.SWI/SNF superfamily-type complex
.PML body
.cytosol
  + 5 more...
56 EBI-389668,EBI-355189 FBXW11  
  .rhythmic process
.positive regulation of transcription, DNA-templated
.negative regulation of transcription, DNA-templated
  + 14 more...
.ubiquitin-protein transferase activity .SCF ubiquitin ligase complex
.cytosol
.centrosome
  + 2 more...
57 EBI-389668,EBI-307461 BTRC  
  .cellular response to organic cyclic compound
.regulation of proteasomal protein catabolic process
.branching involved in mammary gland duct morphogenesis
  + 28 more...
.ligase activity
.ubiquitin-protein transferase activity
.SCF ubiquitin ligase complex
.cytosol
.nucleoplasm
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
bladder167
blood40
bone13
bone marrow61
brain27
cervix41
connective tissue20
embryonic tissue18
eye28
heart11
intestine51
kidney75
larynx85
liver53
lung50
lymph node122
mammary gland6
mouth90
muscle112
nerve64
ovary9
pancreas37
parathyroid48
pharynx73
pituitary gland60
placenta95
prostate31
salivary gland197
skin37
stomach41
testis39
thyroid21
trachea19
uterus77
vascular58
Health State
TissuesTPM*
normal35
bladder carcinoma341
breast (mammary gland) tumor10
cervical tumor57
chondrosarcoma36
colorectal tumor44
gastrointestinal tumor33
germ cell tumor132
glioma139
head and neck tumor97
kidney tumor101
leukemia52
liver tumor72
lung tumor9
non-neoplasia20
ovarian tumor13
retinoblastoma64
skin tumor23
soft tissue/muscle tissue tumor87
uterine tumor88
Developmental Stage
TissuesTPM*
adult61
embryoid body14
blastocyst32
neonate32
fetus19
juvenile35
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue15.4
adrenal gland26.3
appendix16.1
bone marrow28.4
cerebral cortex15.5
colon38.4
duodenum8.5
esophagus16.8
gallbladder16.2
heart muscle6.4
kidney12.2
liver28.9
lung19.5
lymph node21.1
ovary13.6
pancreas7.9
placenta24.3
prostate19.1
salivary gland9.3
skin19.7
small intestine8.3
spleen17.8
stomach14.2
testis9.4
thyroid gland21.2
urinary bladder21.8
Tissues
TissuesExpression level
adrenal glandHigh
appendixHigh
bone marrowHigh
breastHigh
bronchusHigh
cerebellumHigh
cerebral cortexHigh
cervix, uterineHigh
colonHigh
duodenumHigh
endometrium 1High
endometrium 2High
epididymisHigh
esophagusHigh
fallopian tubeHigh
gallbladderHigh
heart muscleHigh
hippocampusHigh
kidneyHigh
lateral ventricleHigh
liverHigh
lungHigh
lymph nodeHigh
nasopharynxHigh
oral mucosaHigh
ovaryHigh
pancreasHigh
parathyroid glandHigh
placentaHigh
prostateHigh
rectumHigh
salivary glandHigh
seminal vesicleHigh
skeletal muscleHigh
skin 1High
skin 2High
small intestineHigh
smooth muscleHigh
soft tissue 1High
soft tissue 2High
spleenHigh
stomach 1High
stomach 2High
testisHigh
thyroid glandHigh
tonsilHigh
urinary bladderHigh
vaginaHigh
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*164785, gene) Mouse double minute 2 homolog; MDM2OMIM
2(#614401, phenotype) Accelerated tumor formation, susceptibility to; ACTFSOMIM
3sarcoma;glioma;colorectal;otherCGP


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