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> Protein (NX_Q01813)
Protein (NX_Q01813)
Protein
Gene SymbolPFKP to neXtProt (NX_Q01813)
DescriptionATP-dependent 6-phosphofructokinase, platelet type
Chromosome10
Location10p15.2 (3108525 ~ 3179904) to Ensembl
Sequene Features : Isoforms 2, Variants 112, PTMs 25 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.activation of mitophagy in response to mitochondrial depolarization
.canonical glycolysis
.carbohydrate phosphorylation
  + 4 more...
.metal ion binding
.protein complex binding
.ATP binding
.6-phosphofructokinase activity
.extracellular exosome
.membrane
.cytosol
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 112 25
2014-09-19protein level
2 92 25
2014-05-27protein level
2 89 26
2014-02-25protein level
2 85 26
2013-12-09protein level
2 64 26
2013-11-01protein level
2 61 21
2013-09-12protein level
2 61 21
2013-08-17protein level
2 61 21
2013-07-15protein level
2 38 9
2013-06-11protein level
2 38 9
2013-02-12protein level
1 16 10
2012-12-20protein level
1 16 10
2012-10-30protein level
1 17 10
2012-10-07protein level
1 17 9
2012-08-24protein level
1 15 9
2012-07-28protein level
1 15 9
2012-06-08protein level
1 18 9
2012-05-07protein level
1 12 9
2012-04-10protein level
1 12 9
2012-01-13protein level
1 12 9
2011-12-20protein level
1 12 9
2011-11-11protein level
1 12 8
2011-08-23protein level
1 12 8
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q01813-1
2 28 4 85541.2864
NX_Q01813-2
5 28 2 85261.2063
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
ascites200
blood163
bone181
bone marrow184
brain231
cervix144
connective tissue147
embryonic tissue112
eye296
heart55
intestine181
kidney251
larynx85
liver155
lung158
lymph203
lymph node66
mammary gland185
mouth60
muscle37
nerve193
ovary88
pancreas178
placenta116
prostate94
salivary gland296
skin185
spleen18
stomach62
testis822
thymus75
thyroid429
umbilical cord145
uterus129
vascular212
Health State
TissuesTPM*
normal130
breast (mammary gland) tumor193
cervical tumor86
chondrosarcoma289
colorectal tumor213
gastrointestinal tumor118
germ cell tumor140
glioma195
head and neck tumor201
kidney tumor551
leukemia179
liver tumor177
lung tumor194
lymphoma152
non-neoplasia175
ovarian tumor78
pancreatic tumor276
primitive neuroectodermal tumor of the CNS165
prostate cancer86
retinoblastoma409
skin tumor263
soft tissue/muscle tissue tumor79
uterine tumor199
Developmental Stage
TissuesTPM*
adult138
embryoid body142
blastocyst130
neonate64
fetus102
infant170
juvenile161
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue20
adrenal gland10.8
appendix33.2
bone marrow7.6
cerebral cortex85.2
colon27.5
duodenum37
esophagus49.1
gallbladder29.4
heart muscle85.7
kidney33.4
liver2.6
lung13.2
lymph node27.4
ovary6.9
pancreas6
placenta15.4
prostate41.6
salivary gland15.8
skin19.5
small intestine44.8
spleen21.2
stomach38.4
testis157.1
thyroid gland33
urinary bladder38.9
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*171840, gene) Phosphofructokinase, platelet type; PFKPOMIM


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