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> Protein (NX_Q02413)
Protein (NX_Q02413)
Protein
Gene SymbolDSG1 to neXtProt (NX_Q02413)
DescriptionDesmoglein-1
Chromosome18
Location18q12.1 (28898052 ~ 28936992) to Ensembl
Sequene Features : Isoforms 2, Variants 244, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.maternal process involved in female pregnancy
.protein stabilization
.response to progesterone
  + 7 more...
.gamma-catenin binding
.toxic substance binding
.calcium ion binding
.extracellular exosome
.desmosome
.lateral plasma membrane
  + 5 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 244 4
2014-09-19protein level
1 187 4
2014-05-27protein level
1 187 4
2014-02-25protein level
1 184 4
2013-12-09protein level
1 155 4
2013-11-01protein level
1 107 4
2013-09-12protein level
1 107 4
2013-08-17protein level
1 107 4
2013-07-15protein level
1 103 4
2013-06-11protein level
1 103 4
2013-02-12protein level
1 58 4
2012-12-20protein level
1 58 4
2012-10-30protein level
1 65 4
2012-10-07protein level
1 65 4
2012-08-24protein level
1 60 4
2012-07-28protein level
1 60 4
2012-06-08protein level
1 61 4
2012-05-07protein level
1 49 4
2012-04-10protein level
1 49 4
2012-01-13protein level
1 25 4
2011-12-20protein level
1 25 4
2011-11-11protein level
1 25 4
2011-08-23protein level
1 25 4
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q02413-1
28 14 0 113675.5411
NX_Q02413-2
1 14 0 42591.5989
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
connective tissue13
eye71
heart145
intestine8
mouth30
muscle9
pharynx24
skin147
stomach10
testis25
Health State
TissuesTPM*
normal17
gastrointestinal tumor25
head and neck tumor14
non-neoplasia134
skin tumor7
soft tissue/muscle tissue tumor15
Developmental Stage
TissuesTPM*
adult10
fetus32
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
esophagus24.7
heart muscle1.1
liver5.4
salivary gland1.2
skin436
testis4.1
Tissues
TissuesExpression level
adrenal glandLow
appendixLow
breastLow
bronchusLow
cervix, uterineMedium
colonLow
duodenumLow
endometrium 2Low
esophagusMedium
fallopian tubeLow
gallbladderLow
kidneyLow
liverLow
lungLow
nasopharynxLow
oral mucosaMedium
pancreasLow
placentaLow
rectumLow
salivary glandLow
seminal vesicleLow
skin 1High
skin 2High
small intestineLow
stomach 1Low
stomach 2Low
testisLow
thyroid glandLow
tonsilLow
urinary bladderHigh
vaginaHigh
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*125670, gene) Desmoglein 1; DSG1OMIM
2(#148700, phenotype) Keratosis palmoplantaris striata i; PPKS1OMIM


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