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> Protein (NX_Q03405)
Protein (NX_Q03405)
Protein
Gene SymbolPLAUR to neXtProt (NX_Q03405)
DescriptionUrokinase plasminogen activator surface receptor
Chromosome19
Location19q13.31 (44150247 ~ 44174699) to Ensembl
Sequene Features : Isoforms 3, Variants 59, PTMs 20 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
.negative regulation of intrinsic apoptotic signaling pathway
.positive regulation of release of cytochrome c from mitochondria
  + 15 more...
.urokinase plasminogen activator receptor activity
.protein domain specific binding
.enzyme binding
  + 2 more...
.invadopodium membrane
.extracellular exosome
.anchored component of membrane
  + 7 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
3 59 20
2014-09-19protein level
3 47 20
2014-05-27protein level
3 46 20
2014-02-25protein level
3 47 20
2013-12-09protein level
3 38 20
2013-11-01protein level
3 38 20
2013-09-12protein level
3 38 20
2013-08-17protein level
3 38 20
2013-07-15protein level
3 27 20
2013-06-11protein level
3 27 20
2013-02-12protein level
3 16 57
2012-12-20protein level
3 17 50
2012-10-30protein level
3 18 50
2012-10-07protein level
3 18 20
2012-08-24protein level
3 14 20
2012-07-28protein level
3 14 20
2012-06-08protein level
3 19 20
2012-05-07protein level
3 19 20
2012-04-10protein level
3 19 20
2012-01-13protein level
3 13 20
2011-12-20protein level
3 13 20
2011-11-11protein level
3 13 20
2011-08-23protein level
3 13 20
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q03405-1
0 14 0 36953.1558
NX_Q03405-2
3 9 0 31242.4894
NX_Q03405-3
1 11 0 31994.9478
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
ascites50
bladder33
blood155
bone111
bone marrow41
brain4
cervix61
connective tissue67
embryonic tissue32
esophagus99
eye28
intestine112
kidney33
larynx85
liver53
lung200
mammary gland52
muscle75
ovary177
pancreas103
pharynx24
placenta14
prostate5
skin99
spleen18
stomach73
testis4
thyroid107
umbilical cord145
uterus21
vascular38
Health State
TissuesTPM*
normal37
bladder carcinoma56
breast (mammary gland) tumor10
chondrosarcoma193
colorectal tumor133
esophageal tumor115
gastrointestinal tumor67
glioma18
head and neck tumor52
kidney tumor29
leukemia84
liver tumor72
lung tumor68
non-neoplasia10
ovarian tumor157
pancreatic tumor85
primitive neuroectodermal tumor of the CNS15
prostate cancer9
retinoblastoma21
skin tumor55
soft tissue/muscle tissue tumor15
uterine tumor55
Developmental Stage
TissuesTPM*
adult81
embryoid body57
blastocyst16
neonate64
fetus17
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue38.1
adrenal gland10.9
appendix72.8
bone marrow360
cerebral cortex4.3
colon20.8
duodenum10
esophagus6.9
gallbladder75.9
heart muscle5.9
kidney4
liver17.8
lung40.3
lymph node10.7
ovary5.6
pancreas5.5
placenta27.2
prostate7.3
salivary gland3.7
skin4.4
small intestine8.8
spleen18.8
stomach23.1
testis3.2
thyroid gland2.9
urinary bladder40.4
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*173391, gene) Plasminogen activator receptor, urokinase-type; PLAUROMIM


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