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> Protein (NX_Q05195)
Protein (NX_Q05195)
Protein
Gene SymbolMXD1 to neXtProt (NX_Q05195)
DescriptionMax dimerization protein 1
Chromosome2
Location2p13.3 (70124820 ~ 70170077) to Ensembl
Sequene Features : Isoforms 2, Variants 33, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.cell proliferation
.multicellular organismal development
.negative regulation of transcription from RNA polymerase II promoter
.transcription corepressor activity
.transcription cofactor activity
.sequence-specific DNA binding transcription factor activity
  + 2 more...
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 33 0
2014-09-19protein level
2 24 0
2014-05-27protein level
2 24 0
2014-02-25protein level
2 24 0
2013-12-09protein level
2 17 0
2013-11-01protein level
2 14 0
2013-09-12protein level
2 14 0
2013-08-17protein level
2 14 0
2013-07-15protein level
2 9 0
2013-06-11protein level
2 9 0
2013-02-12protein level
2 5 0
2012-12-20protein level
2 5 0
2012-10-30protein level
2 6 0
2012-10-07protein level
2 6 0
2012-08-24protein level
2 6 0
2012-07-28protein level
2 6 0
2012-06-08protein level
2 7 0
2012-05-07protein level
2 4 0
2012-04-10protein level
2 4 0
2012-01-13protein level
1 1 0
2011-12-20protein level
1 1 0
2011-11-11protein level
1 1 0
2011-08-23protein level
1 1 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q05195-1
1 8 0 25238.7044
NX_Q05195-2
0 8 0 24012.1617
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-8833637,EBI-751711 MAX  
  .cellular response to peptide hormone stimulus
.retina development in camera-type eye
.neuron apoptotic process
  + 6 more...
.sequence-specific DNA binding
.transcription coactivator activity
.transcription cofactor activity
.sequence-specific DNA binding transcription factor activity
.MLL1 complex
.dendrite
.PML body
  + 3 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
blood130
brain18
cervix20
esophagus99
eye52
heart11
intestine99
kidney42
larynx42
liver19
lung56
mouth136
ovary29
pancreas4
parathyroid97
pharynx122
pituitary gland60
placenta67
prostate52
skin4
spleen18
stomach41
testis27
thymus163
thyroid64
trachea77
uterus25
vascular19
Health State
TissuesTPM*
normal31
adrenal tumor79
colorectal tumor151
esophageal tumor115
gastrointestinal tumor16
glioma9
head and neck tumor134
kidney tumor14
leukemia31
liver tumor31
lung tumor19
non-neoplasia10
ovarian tumor39
pancreatic tumor9
skin tumor7
uterine tumor22
Developmental Stage
TissuesTPM*
adult54
fetus17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue12
adrenal gland3.9
appendix39.8
bone marrow127.2
cerebral cortex5.9
colon30.4
duodenum25.4
esophagus91.9
gallbladder10.4
heart muscle2.1
kidney3.5
liver5.1
lung6.8
lymph node4.1
ovary3.9
pancreas2.5
placenta13.9
prostate4
salivary gland2.7
skin5
small intestine39.3
spleen18.6
stomach16.9
testis6.2
thyroid gland5
urinary bladder12.4
Tissues
TissuesExpression level
adrenal glandLow
appendixMedium
bone marrowMedium
breastLow
bronchusMedium
cerebellumHigh
cerebral cortexMedium
cervix, uterineHigh
colonMedium
duodenumMedium
endometrium 1Low
endometrium 2Low
epididymisMedium
esophagusLow
fallopian tubeLow
gallbladderMedium
heart muscleMedium
hippocampusMedium
kidneyMedium
lateral ventricleMedium
liverLow
lungMedium
lymph nodeMedium
nasopharynxLow
oral mucosaHigh
ovaryMedium
pancreasMedium
parathyroid glandMedium
placentaHigh
prostateLow
rectumMedium
salivary glandMedium
seminal vesicleMedium
skeletal muscleMedium
skin 1Medium
skin 2Medium
small intestineMedium
smooth muscleLow
soft tissue 1Low
soft tissue 2Medium
spleenMedium
stomach 1Medium
stomach 2Medium
testisHigh
thyroid glandMedium
tonsilMedium
urinary bladderMedium
vaginaLow
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*600021, gene) Max dimerization protein 1; MXD1OMIM


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