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> Protein (NX_Q05D60)
Protein (NX_Q05D60)
Protein
Gene SymbolCCDC67 to neXtProt (NX_Q05D60)
DescriptionDeuterosome protein 1
Chromosome11
Location11q21 (93063137 ~ 93171653) to Ensembl
Sequene Features : Isoforms 2, Variants 87, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.multi-ciliated epithelial cell differentiation
.de novo centriole assembly
.cell projection organization
.N/A .deuterosome
.cytoplasm
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 87 0
2014-09-19protein level
2 59 0
2014-05-27transcript level
2 59 0
2014-02-25transcript level
2 58 0
2013-12-09transcript level
2 45 0
2013-11-01transcript level
2 45 0
2013-09-12transcript level
2 45 0
2013-08-17transcript level
2 45 0
2013-07-15transcript level
2 29 0
2013-06-11transcript level
2 29 0
2013-02-12transcript level
2 14 0
2012-12-20transcript level
2 9 0
2012-10-30transcript level
2 17 0
2012-10-07transcript level
2 17 0
2012-08-24transcript level
2 15 0
2012-07-28transcript level
2 15 0
2012-06-08transcript level
2 16 0
2012-05-07transcript level
2 16 0
2012-04-10transcript level
2 16 0
2012-01-13transcript level
2 12 0
2011-12-20transcript level
2 12 0
2011-11-11transcript level
2 12 0
2011-08-23transcript level
2 12 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q05D60-1
11 14 0 70932.511
NX_Q05D60-2
1 14 0 40086.0769
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-748597,EBI-745127 IFIT3  
  .type I interferon signaling pathway
.defense response to virus
.negative regulation of apoptotic process
  + 4 more...
.identical protein binding .cytosol
.mitochondrion
.cytoplasm
2 EBI-748597,EBI-739566 KRT15  
  .activation of mitophagy in response to mitochondrial depolarization
.epidermis development
.scaffold protein binding
.structural constituent of cytoskeleton
.extracellular exosome
.intermediate filament
.nucleus
3 EBI-748597,EBI-359793 TXLNA  
  .activation of mitophagy in response to mitochondrial depolarization
.B cell activation
.cell proliferation
.exocytosis
.high molecular weight B cell growth factor receptor binding
.cytokine activity
.membrane
.cytoplasm
.extracellular region
4 EBI-748597,EBI-7121510 AMPH  
  .synaptic vesicle endocytosis
.learning
.synaptic transmission
.endocytosis
.phospholipid binding .leading edge membrane
.synaptic vesicle membrane
.cell junction
  + 2 more...
5 EBI-748597,EBI-744104 GEM  
  .metaphase plate congression
.chromosome organization
.metabolic process
  + 5 more...
.GDP binding
.GTP binding
.GTPase activity
.magnesium ion binding
.mitotic spindle
.spindle midzone
.midbody
  + 2 more...
6 EBI-748597,EBI-2834260 ESRRG  
  .positive regulation of transcription, DNA-templated
.gene expression
.transcription initiation from RNA polymerase II promoter
.regulation of transcription, DNA-templated
.AF-2 domain binding
.zinc ion binding
.steroid binding
  + 4 more...
.nucleoplasm
7 EBI-748597,EBI-80140 SUMO1  
  .protein localization to nuclear pore
.regulation of interferon-gamma-mediated signaling pathway
.interferon-gamma-mediated signaling pathway
  + 13 more...
.poly(A) RNA binding
.ubiquitin protein ligase binding
.SUMO transferase activity
.transcription factor binding
.synapse
.nuclear membrane
.dendrite
  + 8 more...
8 EBI-748597,EBI-618309 GOLGA2  
  .negative regulation of protein binding
.mitotic cell cycle
.syntaxin binding
.protein kinase binding
.Golgi cisterna membrane
.ER to Golgi transport vesicle
.cis-Golgi network
  + 4 more...
9 EBI-748597,EBI-2555738 ZNF460  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
10 EBI-748597,EBI-10257016 ZNF572  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
11 EBI-748597,EBI-10244131 FBF1  
  .establishment of epithelial cell polarity
.apical junction assembly
.cilium assembly
.organelle organization
.N/A .ciliary transition fiber
.cell junction
.cytosol
  + 3 more...
12 EBI-748597,EBI-2125614 KIFC3  
  .epithelial cell-cell adhesion
.zonula adherens maintenance
.metabolic process
  + 3 more...
.ATPase activity
.ATP binding
.microtubule motor activity
.extracellular exosome
.cytoplasmic vesicle membrane
.zonula adherens
  + 4 more...
13 EBI-748597,EBI-742953 DGCR6L  
  .N/A .N/A .nucleus
14 EBI-748597,EBI-2130429 TRIM54  
  .cell differentiation
.multicellular organismal development
.signal transduction
  + 2 more...
.zinc ion binding
.signal transducer activity
.Z disc
.microtubule associated complex
.microtubule
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
brain1
connective tissue6
lung17
prostate5
salivary gland98
testis39
Health State
TissuesTPM*
normal5
soft tissue/muscle tissue tumor7
Developmental Stage
TissuesTPM*
adult1
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
prostate1.3
testis29.6
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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