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> Protein (NX_Q06136)
Protein (NX_Q06136)
Protein
Gene SymbolKDSR to neXtProt (NX_Q06136)
Description3-ketodihydrosphingosine reductase
Chromosome18
Location18q21.33 (60994959 ~ 61034743) to Ensembl
Sequene Features : Isoforms 2, Variants 20, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.small molecule metabolic process
.sphingolipid biosynthetic process
.3-keto-sphinganine metabolic process
.sphingolipid metabolic process
.3-dehydrosphinganine reductase activity .integral component of membrane
.membrane
.endoplasmic reticulum membrane
  + 2 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 20 0
2014-09-19protein level
1 14 0
2014-05-27protein level
1 14 0
2014-02-25protein level
1 14 0
2013-12-09protein level
1 10 0
2013-11-01protein level
1 9 0
2013-09-12protein level
1 9 0
2013-08-17protein level
1 9 0
2013-07-15protein level
1 7 0
2013-06-11protein level
1 7 0
2013-02-12protein level
1 1 0
2012-12-20protein level
1 1 0
2012-10-30protein level
1 2 0
2012-10-07protein level
1 2 0
2012-08-24protein level
1 1 0
2012-07-28protein level
1 1 0
2012-06-08protein level
1 1 0
2012-05-07protein level
1 1 0
2012-04-10protein level
1 1 0
2012-01-13protein level
1 2 0
2011-12-20protein level
1 2 0
2011-11-11protein level
1 2 0
2011-08-23protein level
1 2 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q06136-1
4 9 0 36163.5292
NX_Q06136-2
1 9 0 29139.8302
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue155
adrenal gland60
ascites75
bladder100
blood98
bone83
bone marrow41
brain114
cervix41
connective tissue160
embryonic tissue37
esophagus99
eye43
heart55
intestine94
kidney61
larynx42
liver87
lung29
lymph node44
mammary gland105
mouth15
muscle28
ovary9
pancreas14
parathyroid145
pharynx49
placenta81
prostate31
salivary gland98
skin66
spleen18
stomach135
testis45
thymus112
thyroid85
trachea154
uterus77
vascular96
Health State
TissuesTPM*
normal75
adrenal tumor158
bladder carcinoma56
breast (mammary gland) tumor107
cervical tumor28
chondrosarcoma108
colorectal tumor35
esophageal tumor115
gastrointestinal tumor126
germ cell tumor98
glioma37
head and neck tumor52
kidney tumor43
leukemia63
liver tumor145
lung tumor19
non-neoplasia206
ovarian tumor13
pancreatic tumor19
primitive neuroectodermal tumor of the CNS220
prostate cancer19
retinoblastoma86
skin tumor7
uterine tumor33
Developmental Stage
TissuesTPM*
adult73
embryoid body14
blastocyst32
neonate64
fetus44
infant42
juvenile467
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue29.9
adrenal gland25.1
appendix18.4
bone marrow7.4
cerebral cortex25.9
colon22.3
duodenum18.4
esophagus26.1
gallbladder25.7
heart muscle19.9
kidney24.2
liver30.5
lung23.1
lymph node13.1
ovary34.2
pancreas9.9
placenta25.7
prostate23.4
salivary gland13.3
skin28.9
small intestine18.9
spleen14.7
stomach18.6
testis13.2
thyroid gland24.3
urinary bladder25.7
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*136440, gene) Follicular lymphoma variant translocation 1; FVT1OMIM


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