Home| Contact Us

HOME SEARCH STATISTICS
> Protein (NX_Q06265)
Protein (NX_Q06265)
Protein
Gene SymbolEXOSC9 to neXtProt (NX_Q06265)
DescriptionExosome complex component RRP45
Chromosome4
Location4q27 (122722472 ~ 122738176) to Ensembl
Sequene Features : Isoforms 4, Variants 66, PTMs 11 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.RNA phosphodiester bond hydrolysis, exonucleolytic
.nuclear polyadenylation-dependent rRNA catabolic process
.nuclear mRNA surveillance
  + 7 more...
.poly(A) RNA binding
.AU-rich element binding
.RNA binding
.3'-5'-exoribonuclease activity
.extracellular exosome
.intermediate filament cytoskeleton
.cytosol
  + 7 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
4 66 11
2014-09-19protein level
4 49 11
2014-05-27protein level
4 49 11
2014-02-25protein level
4 49 11
2013-12-09protein level
4 36 11
2013-11-01protein level
4 35 10
2013-09-12protein level
4 35 10
2013-08-17protein level
4 35 10
2013-07-15protein level
4 20 5
2013-06-11protein level
4 20 5
2013-02-12protein level
4 10 20
2012-12-20protein level
4 10 20
2012-10-30protein level
4 14 20
2012-10-07protein level
4 14 5
2012-08-24protein level
4 14 5
2012-07-28protein level
4 14 5
2012-06-08protein level
4 14 5
2012-05-07protein level
4 10 5
2012-04-10protein level
4 10 5
2012-01-13protein level
4 4 5
2011-12-20protein level
4 4 5
2011-11-11protein level
4 4 5
2011-08-23protein level
4 4 5
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q06265-1
0 16 0 48917.9615
NX_Q06265-2
0 16 0 50770.8672
NX_Q06265-3
0 13 0 39209.9692
NX_Q06265-4
0 13 0 41062.8749
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-347966,EBI-371823 EXOSC4  
  .RNA phosphodiester bond hydrolysis, exonucleolytic
.polyadenylation-dependent snoRNA 3'-end processing
.histone mRNA catabolic process
  + 14 more...
.AU-rich element binding
.3'-5'-exoribonuclease activity
.transcriptionally active chromatin
.cytosol
.cytoplasm
  + 5 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
bladder100
blood130
bone167
bone marrow143
brain28
cervix103
connective tissue6
embryonic tissue108
eye33
intestine34
kidney47
liver24
lung14
lymph45
lymph node111
mammary gland33
muscle75
ovary29
pharynx49
placenta35
prostate58
salivary gland49
skin33
testis73
thymus25
thyroid21
tonsil235
trachea19
uterus25
vascular19
Health State
TissuesTPM*
normal33
adrenal tumor79
bladder carcinoma227
breast (mammary gland) tumor32
cervical tumor28
chondrosarcoma120
colorectal tumor53
germ cell tumor68
glioma46
kidney tumor14
leukemia158
liver tumor31
lung tumor9
lymphoma41
non-neoplasia31
ovarian tumor39
primitive neuroectodermal tumor of the CNS62
prostate cancer105
retinoblastoma107
skin tumor15
soft tissue/muscle tissue tumor55
uterine tumor55
Developmental Stage
TissuesTPM*
adult31
embryoid body114
blastocyst97
fetus26
infant85
juvenile89
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue13
adrenal gland17.6
appendix24.9
bone marrow44.6
cerebral cortex13.3
colon15.1
duodenum11.8
esophagus15
gallbladder14.9
heart muscle15.1
kidney12.5
liver9.8
lung17.3
lymph node36.7
ovary18.4
pancreas6.1
placenta17.7
prostate14.5
salivary gland9.7
skin15.2
small intestine13.9
spleen21.2
stomach13.6
testis51.1
thyroid gland14.1
urinary bladder18.5
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*606180, gene) Exosome component 9; EXOSC9OMIM


#424, YPRC/BPRC, Industry-University Research Center, Yonsei Univ., Seodaemun-gu, Seoul, Korea, 120-749
Tel: +82-2-2123-6626, Fax: +82-2-393-6589
2014-2019 (C) Yonsei Proteome Research Center