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> Protein (NX_Q07866)
Protein (NX_Q07866)
Protein
Gene SymbolKLC1 to neXtProt (NX_Q07866)
DescriptionKinesin light chain 1
Chromosome14
Location14q32.33 (104028233 ~ 104167888) to Ensembl
Sequene Features : Isoforms 10, Variants 50, PTMs 12 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.stress granule disassembly
.antigen processing and presentation of exogenous peptide antigen via MHC class II
.viral process
  + 4 more...
.microtubule motor activity
.motor activity
.growth cone
.cytoplasmic membrane-bounded vesicle
.membrane
  + 3 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
10 50 12
2014-09-19protein level
10 33 12
2014-05-27protein level
10 33 13
2014-02-25protein level
10 33 13
2013-12-09protein level
10 24 13
2013-11-01protein level
10 22 12
2013-09-12protein level
10 22 13
2013-08-17protein level
10 22 13
2013-07-15protein level
10 13 13
2013-06-11protein level
10 13 13
2013-02-12protein level
9 3 75
2012-12-20protein level
9 3 75
2012-10-30protein level
9 10 75
2012-10-07protein level
9 10 12
2012-08-24protein level
9 10 12
2012-07-28protein level
9 8 12
2012-06-08protein level
9 12 12
2012-05-07protein level
9 12 12
2012-04-10protein level
9 12 12
2012-01-13protein level
9 8 12
2011-12-20protein level
9 8 12
2011-11-11protein level
9 8 12
2011-08-23protein level
9 6 11
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q07866-1
1 22 9 65268.6847
NX_Q07866-10
1 22 9 69721.9707
NX_Q07866-2
1 21 9 63776.0034
NX_Q07866-3
1 22 9 64279.2596
NX_Q07866-4
0 25 9 71951.1707
NX_Q07866-5
0 23 9 69923.2194
NX_Q07866-6
1 24 9 70961.7456
NX_Q07866-7
1 24 9 66250.1896
NX_Q07866-8
1 21 9 62786.5783
NX_Q07866-9
0 24 9 72352.4719
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-721019,EBI-752094 BNIP2  
  .positive regulation of muscle cell differentiation
.positive regulation of GTPase activity
.negative regulation of apoptotic process
  + 2 more...
.identical protein binding
.calcium ion binding
.GTPase activator activity
.perinuclear region of cytoplasm
.intracellular membrane-bounded organelle
.cytosol
  + 2 more...
2 EBI-721019,EBI-948001 KRT31  
  .epidermis development .structural constituent of cytoskeleton .extracellular exosome
.intermediate filament
.extracellular space
3 EBI-721019,EBI-10173858 CCDC114  
  .outer dynein arm assembly .N/A .outer dynein arm
.cilium
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
adrenal gland30
ascites225
blood89
bone97
bone marrow41
brain443
cervix61
connective tissue60
ear62
embryonic tissue145
esophagus99
eye181
heart78
intestine90
kidney56
larynx127
liver63
lung116
lymph22
lymph node89
mammary gland105
mouth90
muscle56
nerve643
ovary137
pancreas56
pharynx24
pituitary gland363
placenta63
prostate79
skin90
spleen56
stomach62
testis45
thymus37
thyroid171
trachea19
uterus137
vascular116
Health State
TissuesTPM*
normal194
breast (mammary gland) tumor171
cervical tumor86
chondrosarcoma84
colorectal tumor106
esophageal tumor115
gastrointestinal tumor126
germ cell tumor186
glioma177
head and neck tumor134
kidney tumor87
leukemia52
liver tumor72
lung tumor116
lymphoma27
non-neoplasia134
ovarian tumor91
pancreatic tumor85
primitive neuroectodermal tumor of the CNS133
prostate cancer57
retinoblastoma258
skin tumor95
soft tissue/muscle tissue tumor111
uterine tumor166
Developmental Stage
TissuesTPM*
adult110
embryoid body128
blastocyst146
neonate32
fetus337
infant127
juvenile287
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue44.8
adrenal gland47
appendix39.4
bone marrow29.8
cerebral cortex216.6
colon32.6
duodenum20.8
esophagus36.8
gallbladder35.2
heart muscle53.4
kidney20.7
liver15.2
lung57.4
lymph node39.4
ovary39.8
pancreas17.1
placenta34.6
prostate40.6
salivary gland33.3
skin53.2
small intestine29.8
spleen53.5
stomach37.8
testis42.4
thyroid gland30.5
urinary bladder36.8
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*600025, gene) Kinesin light chain 1; KLC1OMIM


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