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> Protein (NX_Q08379)
Protein (NX_Q08379)
Protein
Gene SymbolGOLGA2 to neXtProt (NX_Q08379)
DescriptionGolgin subfamily A member 2
Chromosome9
Location9q34.11 (131018108 ~ 131038274) to Ensembl
Sequene Features : Isoforms 2, Variants 96, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.negative regulation of protein binding
.mitotic cell cycle
.syntaxin binding
.protein kinase binding
.Golgi cisterna membrane
.ER to Golgi transport vesicle
.cis-Golgi network
  + 4 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 96 4
2014-09-19protein level
2 78 4
2014-05-27protein level
2 78 4
2014-02-25protein level
2 76 4
2013-12-09protein level
2 52 4
2013-11-01protein level
2 51 4
2013-09-12protein level
2 51 5
2013-08-17protein level
2 51 5
2013-07-15protein level
2 36 5
2013-06-11protein level
2 36 5
2013-02-12protein level
2 24 9
2012-12-20protein level
2 25 9
2012-10-30protein level
2 30 9
2012-10-07protein level
2 30 6
2012-08-24protein level
2 25 6
2012-07-28protein level
2 24 6
2012-06-08protein level
2 26 6
2012-05-07protein level
2 26 6
2012-04-10protein level
2 26 6
2012-01-13protein level
2 14 6
2011-12-20protein level
2 14 6
2011-11-11protein level
2 14 4
2011-08-23protein level
2 14 4
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q08379-1
18 25 1 113016.3163
NX_Q08379-2
0 25 1 70428.8123
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-618309,EBI-5453796 GTPBP10  
  .ribosome biogenesis .poly(A) RNA binding
.GTP binding
.GTPase activity
.magnesium ion binding
.mitochondrion
.nucleolus
.chromosome
2 EBI-618309,EBI-2559305 VPS37C  
  .intracellular transport of virus
.membrane organization
.viral protein processing
  + 5 more...
.calcium-dependent protein binding .extracellular exosome
.late endosome membrane
.endosome membrane
.ESCRT I complex
3 EBI-618309,EBI-346930 PIK3R2  
  .regulation of small GTPase mediated signal transduction
.leukocyte migration
.T cell receptor signaling pathway
  + 25 more...
.protein heterodimerization activity
.1-phosphatidylinositol-3-kinase regulator activity
.receptor tyrosine kinase binding
.protein phosphatase binding
.phosphatidylinositol 3-kinase complex
.cytosol
.nucleus
4 EBI-618309,EBI-618295 STK25  
  .Golgi reassembly
.establishment of Golgi localization
.Golgi localization
  + 12 more...
.metal ion binding
.protein homodimerization activity
.ATP binding
  + 2 more...
.extracellular exosome
.Golgi apparatus
.cytoplasm
5 EBI-618309,EBI-2513988 LIN7A  
  .protein localization to basolateral plasma membrane
.inner ear development
.synaptic vesicle transport
  + 7 more...
.L27 domain binding .MPP7-DLG1-LIN7 complex
.extracellular exosome
.postsynaptic membrane
  + 7 more...
6 EBI-618309,EBI-351829 ARPC3  
  .ephrin receptor signaling pathway
.innate immune response
.Fc-gamma receptor signaling pathway involved in phagocytosis
  + 4 more...
.structural constituent of cytoskeleton .extracellular exosome
.lamellipodium
.membrane
  + 4 more...
7 EBI-618309,EBI-8646694 DCX  
  .dendrite morphogenesis
.axon extension
.protein autophosphorylation
  + 8 more...
.protein kinase binding
.calcium-dependent protein serine/threonine kinase activity
.microtubule binding
  + 2 more...
.neuron projection
.microtubule associated complex
.microtubule
  + 4 more...
8 EBI-618309,EBI-1053424 PRKAB2  
  .membrane organization
.regulation of protein kinase activity
.small molecule metabolic process
  + 13 more...
.identical protein binding .AMP-activated protein kinase complex
.cytosol
.nucleoplasm
9 EBI-618309,EBI-355720 NUDT21  
  .protein tetramerization
.mRNA 3'-end processing
.gene expression
  + 6 more...
.poly(A) RNA binding
.histone deacetylase binding
.protein homodimerization activity
  + 3 more...
.paraspeckles
.mRNA cleavage factor complex
.centrosome
  + 2 more...
10 EBI-618309,EBI-713867 PQBP1  
  .regulation of dendrite morphogenesis
.regulation of RNA splicing
.neuron projection development
  + 3 more...
.ribonucleoprotein complex binding
.transcription coactivator activity
.DNA binding
.neuronal ribonucleoprotein granule
.nuclear speck
.cytoplasmic stress granule
  + 3 more...
11 EBI-618309,EBI-711802 ATP6V1G1  
  .phagosome maturation
.transmembrane transport
.interaction with host
  + 4 more...
.ATPase binding
.hydrogen-exporting ATPase activity, phosphorylative mechanism
.extracellular exosome
.vacuolar proton-transporting V-type ATPase complex
.plasma membrane
  + 2 more...
12 EBI-618309,EBI-743272 USP2  
  .regulation of proteasomal protein catabolic process
.protein stabilization
.positive regulation of skeletal muscle tissue development
  + 11 more...
.metal ion binding
.ubiquitin protein ligase binding
.cyclin binding
  + 2 more...
.perinuclear region of cytoplasm
.cell cortex
.centrosome
  + 2 more...
13 EBI-618309,EBI-714732 ADAP1  
  .positive regulation of GTPase activity
.regulation of GTPase activity
.cell surface receptor signaling pathway
.inositol 1,3,4,5 tetrakisphosphate binding
.zinc ion binding
.phosphatidylinositol-3,4,5-trisphosphate binding
.GTPase activator activity
.plasma membrane
.cytoplasm
.nucleus
14 EBI-618309,EBI-366632 EIF3G  
  .cellular protein metabolic process
.gene expression
.regulation of translational initiation
  + 3 more...
.poly(A) RNA binding
.translation initiation factor activity
.nucleotide binding
.perinuclear region of cytoplasm
.eukaryotic 48S preinitiation complex
.eukaryotic 43S preinitiation complex
  + 3 more...
15 EBI-618309,EBI-348555 PIAS2  
  .negative regulation of androgen receptor signaling pathway
.positive regulation of transcription from RNA polymerase II promoter
.positive regulation of transcription, DNA-templated
  + 7 more...
.SUMO ligase activity
.androgen receptor binding
.ligase activity
  + 4 more...
.nuclear speck
.PML body
.nucleoplasm
.nucleus
16 EBI-618309,EBI-1050106 BCAS2  
  .gene expression
.RNA splicing
.mRNA splicing, via spliceosome
.RNA splicing, via transesterification reactions
.N/A .cell junction
.nucleolus
.spliceosomal complex
  + 2 more...
17 EBI-618309,EBI-2880203 NEBL  
  .cardiac muscle thin filament assembly .actin filament binding
.filamin binding
.structural constituent of muscle
  + 2 more...
.extracellular exosome
.I band
.Z disc
.stress fiber
18 EBI-618309,EBI-7543896 SCEL  
  .keratinocyte differentiation
.embryo development
.epidermis development
.zinc ion binding .extracellular exosome
.cytoplasm
.cornified envelope
19 EBI-618309,EBI-750559 SLU7  
  .cellular response to heat
.intracellular protein transport
.mRNA splicing, via spliceosome
  + 3 more...
.pre-mRNA 3'-splice site binding
.zinc ion binding
.second spliceosomal transesterification activity
.catalytic step 2 spliceosome
.intracellular membrane-bounded organelle
.small nuclear ribonucleoprotein complex
  + 6 more...
20 EBI-618309,EBI-751540 GPANK1  
  .N/A .nucleic acid binding .N/A
21 EBI-618309,EBI-1783068 MBD3  
  .ATP-dependent chromatin remodeling
.histone acetylation
.tissue development
  + 5 more...
.methyl-CpG binding
.chromatin binding
.DNA binding
.protein complex
.NuRD complex
.cytoplasm
  + 3 more...
22 EBI-618309,EBI-1757866 MOS  
  .negative regulation of metaphase/anaphase transition of meiotic cell cycle
.establishment of meiotic spindle orientation
.protein autophosphorylation
  + 6 more...
.ATP binding
.MAP kinase kinase kinase activity
.protein serine/threonine kinase activity
.cytoplasm
23 EBI-618309,EBI-702198 KRT6A  
  .activation of mitophagy in response to mitochondrial depolarization
.wound healing
.cell differentiation
  + 3 more...
.structural constituent of cytoskeleton .extracellular exosome
.keratin filament
.membrane
.nucleus
24 EBI-618309,EBI-740907 KRT6B  
  .ectoderm development .structural constituent of cytoskeleton .extracellular exosome
.keratin filament
25 EBI-618309,EBI-297888 KRT18  
  .hepatocyte apoptotic process
.extrinsic apoptotic signaling pathway
.intermediate filament cytoskeleton organization
  + 6 more...
.scaffold protein binding
.poly(A) RNA binding
.structural molecule activity
.cell periphery
.extracellular exosome
.perinuclear region of cytoplasm
  + 6 more...
26 EBI-618309,EBI-1053651 SNRPB2  
  .gene expression
.RNA splicing
.mRNA processing
  + 2 more...
.snRNA binding
.nucleotide binding
.catalytic step 2 spliceosome
.nucleolus
.U2 snRNP
  + 2 more...
27 EBI-618309,EBI-351158 TPM1  
  .cardiac muscle contraction
.ventricular cardiac muscle tissue morphogenesis
.positive regulation of stress fiber assembly
  + 15 more...
.structural constituent of muscle
.cytoskeletal protein binding
.structural constituent of cytoskeleton
.actin binding
.ruffle membrane
.bleb
.filamentous actin
  + 5 more...
28 EBI-618309,EBI-744302 GFAP  
  .long-term synaptic potentiation
.Bergmann glial cell differentiation
.regulation of neurotransmitter uptake
  + 7 more...
.structural constituent of cytoskeleton .astrocyte end-foot
.cell body
.membrane
  + 3 more...
29 EBI-618309,EBI-372475 SNRPB  
  .activation of mitophagy in response to mitochondrial depolarization
.ncRNA metabolic process
.mRNA 3'-end processing
  + 9 more...
.histone pre-mRNA DCP binding
.poly(A) RNA binding
.histone pre-mRNA 3'end processing complex
.catalytic step 2 spliceosome
.U2-type prespliceosome
  + 14 more...
30 EBI-618309,EBI-10177272 ZNF250  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.nucleus
31 EBI-618309,EBI-745290 HOXB9  
  .cell chemotaxis
.canonical Wnt signaling pathway
.embryonic skeletal system development
  + 4 more...
.sequence-specific DNA binding .mitochondrion
.nucleoplasm
32 EBI-618309,EBI-1170392 LGALS3  
  .negative regulation of extrinsic apoptotic signaling pathway
.negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell
.negative regulation of immunological synapse formation
  + 19 more...
.poly(A) RNA binding
.laminin binding
.chemoattractant activity
  + 2 more...
.extracellular exosome
.membrane
.external side of plasma membrane
  + 8 more...
33 EBI-618309,EBI-489611 NCF2  
  .phagosome maturation
.response to hyperoxia
.interaction with host
  + 20 more...
.electron carrier activity
.protein C-terminus binding
.NADPH oxidase complex
.phagolysosome
.cytosol
  + 3 more...
34 EBI-618309,EBI-2806671 GATA2  
  .regulation of forebrain neuron differentiation
.negative regulation of neural precursor cell proliferation
.GABAergic neuron differentiation
  + 29 more...
.C2H2 zinc finger domain binding
.zinc ion binding
.transcription factor binding
  + 5 more...
.protein complex
.nucleoplasm
35 EBI-618309,EBI-395261 CCNC  
  .positive regulation of transcription from RNA polymerase II promoter
.gene expression
.Notch signaling pathway
  + 4 more...
.N/A .mediator complex
.nucleoplasm
36 EBI-618309,EBI-359352 PSMA1  
  .positive regulation of canonical Wnt signaling pathway
.negative regulation of canonical Wnt signaling pathway
.regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
  + 23 more...
.threonine-type endopeptidase activity
.endopeptidase activity
.RNA binding
.extracellular exosome
.proteasome core complex, alpha-subunit complex
.polysome
  + 7 more...
37 EBI-618309,EBI-359310 PSMA4  
  .positive regulation of canonical Wnt signaling pathway
.negative regulation of canonical Wnt signaling pathway
.regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
  + 23 more...
.threonine-type endopeptidase activity
.endopeptidase activity
.extracellular exosome
.intracellular membrane-bounded organelle
.proteasome core complex, alpha-subunit complex
  + 8 more...
38 EBI-618309,EBI-739696 LMO2  
  .cellular response to thyroid hormone stimulus
.positive regulation of transcription from RNA polymerase II promoter
.negative regulation of erythrocyte differentiation
  + 3 more...
.E-box binding
.cofactor binding
.bHLH transcription factor binding
  + 7 more...
.transcription factor complex
.nucleus
39 EBI-618309,EBI-8639312 LMO1  
  .positive regulation of transcription from RNA polymerase II promoter
.negative regulation of transcription from RNA polymerase II promoter
.zinc ion binding .nucleus
40 EBI-618309,EBI-351257 DDX6  
  .exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
.cytoplasmic mRNA processing body assembly
.viral RNA genome packaging
  + 4 more...
.poly(A) RNA binding
.protein domain specific binding
.ATP binding
  + 3 more...
.intracellular membrane-bounded organelle
.RISC complex
.membrane
  + 5 more...
41 EBI-618309,EBI-751388 ITPKB  
  .positive regulation of alpha-beta T cell differentiation
.positive regulation of Ras protein signal transduction
.positive thymic T cell selection
  + 5 more...
.inositol-1,4,5-trisphosphate 3-kinase activity
.ATP binding
.cytosol
42 EBI-618309,EBI-1391623 NOS3  
  .negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
.phagosome maturation
.negative regulation of calcium ion transport
  + 34 more...
.NADP binding
.flavin adenine dinucleotide binding
.cadmium ion binding
  + 8 more...
.endocytic vesicle membrane
.caveola
.plasma membrane
  + 5 more...
43 EBI-618309,EBI-1046676 CORO1A  
  .cellular response to interleukin-4
.early endosome to recycling endosome transport
.regulation of release of sequestered calcium ion into cytosol
  + 23 more...
.actin filament binding
.poly(A) RNA binding
.phosphatidylinositol 3-kinase binding
  + 6 more...
.extracellular exosome
.phagocytic vesicle
.protein complex
  + 12 more...
44 EBI-618309,EBI-355924 MCM7  
  .cellular response to epidermal growth factor stimulus
.response to drug
.regulation of phosphorylation
  + 8 more...
.ATP binding
.single-stranded DNA binding
.DNA helicase activity
.MCM complex
.membrane
.cytosol
  + 3 more...
45 EBI-618309,EBI-359793 TXLNA  
  .activation of mitophagy in response to mitochondrial depolarization
.B cell activation
.cell proliferation
.exocytosis
.high molecular weight B cell growth factor receptor binding
.cytokine activity
.membrane
.cytoplasm
.extracellular region
46 EBI-618309,EBI-2875746 ARL4A  
  .brown fat cell differentiation
.small GTPase mediated signal transduction
.GTP binding .plasma membrane
.cytoplasm
.nucleolus
.nucleus
47 EBI-618309,EBI-2564105 KRT6C  
  .intermediate filament cytoskeleton organization .structural molecule activity .extracellular exosome
.keratin filament
.intermediate filament
48 EBI-618309,EBI-750494 SMCP  
  .sperm motility
.penetration of zona pellucida
.N/A .mitochondrial membrane
.mitochondrion
.cytoplasm
49 EBI-618309,EBI-741406 CCNH  
  .positive regulation of viral transcription
.positive regulation of transcription from RNA polymerase II promoter
.negative regulation of gene expression, epigenetic
  + 20 more...
.cyclin-dependent protein serine/threonine kinase regulator activity
.kinase activity
.TFIIK complex
.cyclin-dependent protein kinase activating kinase holoenzyme complex
.holo TFIIH complex
  + 2 more...
50 EBI-618309,EBI-744104 GEM  
  .metaphase plate congression
.chromosome organization
.metabolic process
  + 5 more...
.GDP binding
.GTP binding
.GTPase activity
.magnesium ion binding
.mitotic spindle
.spindle midzone
.midbody
  + 2 more...
51 EBI-618309,EBI-1048159 MFAP1  
  .extracellular matrix organization .poly(A) RNA binding .extracellular region
.microfibril
52 EBI-618309,EBI-749995 TCL1A  
  .stem cell maintenance
.multicellular organismal development
.N/A .pronucleus
.cell cortex
.endoplasmic reticulum
53 EBI-618309,EBI-308629 HDAC4  
  .histone H4 deacetylation
.histone H3 deacetylation
.response to interleukin-1
  + 29 more...
.NAD-dependent histone deacetylase activity (H3-K18 specific)
.repressing transcription factor binding
.NAD-dependent histone deacetylase activity (H4-K16 specific)
  + 12 more...
.actomyosin
.A band
.neuromuscular junction
  + 7 more...
54 EBI-618309,EBI-10216117 RGS8  
  .positive regulation of GTPase activity
.termination of G-protein coupled receptor signaling pathway
.GTPase activator activity .plasma membrane
.cytoplasm
55 EBI-618309,EBI-10216195 SELV  
  .cell redox homeostasis .selenium binding .N/A
56 EBI-618309,EBI-752037 RAB2A  
  .Rab protein signal transduction
.metabolic process
.Golgi organization
  + 3 more...
.GDP binding
.GTP binding
.GTPase activity
.extracellular exosome
.melanosome
.endoplasmic reticulum-Golgi intermediate compartment membrane
  + 4 more...
57 EBI-618309,EBI-299134 MAGOH  
  .mRNA 3'-end processing
.gene expression
.RNA splicing
  + 7 more...
.poly(A) RNA binding .catalytic step 2 spliceosome
.exon-exon junction complex
.nuclear speck
  + 3 more...
58 EBI-618309,EBI-2798728 LMO4  
  .regulation of cell activation
.thymus development
.positive regulation of transcription from RNA polymerase II promoter
  + 8 more...
.zinc ion binding
.transcription factor binding
.sequence-specific DNA binding transcription factor activity
.enhancer sequence-specific DNA binding
.transcription factor complex
59 EBI-618309,EBI-10220734 GNG5  
  .cellular response to glucagon stimulus
.small molecule metabolic process
.synaptic transmission
  + 3 more...
.PDZ domain binding
.signal transducer activity
.GTPase activity
.extracellular exosome
.membrane
.plasma membrane
.heterotrimeric G-protein complex
60 EBI-618309,EBI-80168 UBE2I  
  .positive regulation of SUMO transferase activity
.cell division
.positive regulation of sequence-specific DNA binding transcription factor activity
  + 14 more...
.RING-like zinc finger domain binding
.SUMO conjugating enzyme activity
.poly(A) RNA binding
  + 6 more...
.sumoylated E2 ligase complex
.transferase complex
.synapse
  + 7 more...
61 EBI-618309,EBI-2514218 TFAP4  
  .positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
.cellular response to dexamethasone stimulus
.negative regulation of cell cycle arrest
  + 12 more...
.E-box binding
.transcription regulatory region DNA binding
.sequence-specific DNA binding
  + 6 more...
.transcriptional repressor complex
.nucleus
62 EBI-618309,EBI-711925 ZBTB16  
  .positive regulation of cartilage development
.cartilage development
.positive regulation of NK T cell differentiation
  + 22 more...
.metal ion binding
.protein homodimerization activity
.identical protein binding
  + 4 more...
.transcriptional repressor complex
.nuclear speck
.PML body
  + 5 more...
63 EBI-618309,EBI-748597 CCDC67  
  .multi-ciliated epithelial cell differentiation
.de novo centriole assembly
.cell projection organization
.N/A .deuterosome
.cytoplasm
64 EBI-618309,EBI-746238 CDK18  
  .N/A .ATP binding
.cyclin-dependent protein serine/threonine kinase activity
.N/A
65 EBI-618309,EBI-717810 AES  
  .positive regulation of anoikis
.negative regulation of canonical Wnt signaling pathway
.response to interleukin-1
  + 12 more...
.transcription corepressor activity .nucleus
66 EBI-618309,EBI-715275 DMTN  
  .positive regulation of integrin-mediated signaling pathway
.positive regulation of platelet aggregation
.positive regulation of substrate adhesion-dependent cell spreading
  + 27 more...
.protein self-association
.spectrin binding
.receptor binding
.actin binding
.perinuclear region of cytoplasm
.cell projection membrane
.platelet dense tubular network membrane
  + 8 more...
67 EBI-618309,EBI-10186132 ARL16  
  .small GTPase mediated signal transduction .GTP binding .intracellular
68 EBI-618309,EBI-346946 LCP2  
  .T cell receptor signaling pathway
.cytokine secretion
.positive regulation of protein kinase activity
  + 8 more...
.N/A .cell-cell junction
.cytosol
69 EBI-618309,EBI-1181405 PRKAA1  
  .negative regulation of glucose import in response to insulin stimulus
.regulation of energy homeostasis
.response to camptothecin
  + 42 more...
.[acetyl-CoA carboxylase] kinase activity
.tau-protein kinase activity
.[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity
  + 7 more...
.AMP-activated protein kinase complex
.apical plasma membrane
.cytosol
  + 4 more...
70 EBI-618309,EBI-714158 PIN1  
  .negative regulation of cell motility
.negative regulation of ERK1 and ERK2 cascade
.regulation of pathway-restricted SMAD protein phosphorylation
  + 11 more...
.phosphothreonine binding
.phosphoserine binding
.GTPase activating protein binding
  + 2 more...
.midbody
.nuclear speck
.cytoplasm
  + 2 more...
71 EBI-618309,EBI-632715 SNW1  
  .cellular response to retinoic acid
.positive regulation of vitamin D receptor signaling pathway
.regulation of vitamin D receptor signaling pathway
  + 19 more...
.SMAD binding
.poly(A) RNA binding
.retinoic acid receptor binding
  + 5 more...
.catalytic step 2 spliceosome
.nuclear matrix
.spliceosomal complex
  + 3 more...
72 EBI-618309,EBI-358049 BYSL  
  .cell proliferation
.female pregnancy
.cell adhesion
  + 2 more...
.poly(A) RNA binding .apical part of cell
.intracellular membrane-bounded organelle
.membrane
  + 3 more...
73 EBI-618309,EBI-702370 TRIM29  
  .negative regulation of protein localization to nucleus
.transcription from RNA polymerase II promoter
.negative regulation of transcription from RNA polymerase II promoter
.zinc ion binding
.sequence-specific DNA binding transcription factor activity
.intermediate filament cytoskeleton
.cytoplasm
.nucleoplasm
74 EBI-618309,EBI-6654703 RBM39  
  .RNA splicing
.mRNA processing
.RNA processing
  + 2 more...
.poly(A) RNA binding
.nucleotide binding
.nuclear speck
.microtubule cytoskeleton
.microtubule organizing center
.nucleoplasm
75 EBI-618309,EBI-372619 GSE1  
  .N/A .N/A .N/A
76 EBI-618309,EBI-742828 LASP1  
  .positive regulation of signal transduction
.ion transport
.ion transmembrane transporter activity
.zinc ion binding
.SH3/SH2 adaptor activity
.extracellular exosome
.cortical actin cytoskeleton
.focal adhesion
77 EBI-618309,EBI-3048577 RAB39A  
  .phagosome-lysosome fusion
.phagosome acidification
.Rab protein signal transduction
  + 2 more...
.GTP binding
.GTPase activity
.phagocytic vesicle
.phagocytic vesicle membrane
.plasma membrane
.Golgi apparatus
78 EBI-618309,EBI-10217913 RTP5  
  .N/A .N/A .integral component of membrane
79 EBI-618309,EBI-399257 MORF4L2  
  .positive regulation of striated muscle cell differentiation
.positive regulation of transcription from RNA polymerase II promoter
.regulation of growth
  + 4 more...
.N/A .nucleolus
.nucleoplasm
80 EBI-618309,EBI-1058871 UBE3C  
  .protein ubiquitination involved in ubiquitin-dependent protein catabolic process
.protein polyubiquitination
.ligase activity
.ubiquitin-protein transferase activity
.cytoplasm
.nucleus
.intracellular
.proteasome complex
81 EBI-618309,EBI-748280 DLGAP5  
  .positive regulation of mitotic metaphase/anaphase transition
.signaling
.dephosphorylation
  + 2 more...
.phosphoprotein phosphatase activity .spindle pole centrosome
.microtubule organizing center
.cytoplasm
.nucleus
82 EBI-618309,EBI-710310 TCEA2  
  .positive regulation of transcription from RNA polymerase II promoter
.regulation of DNA-templated transcription, elongation
.DNA-templated transcription, elongation
.zinc ion binding
.DNA binding
.transcription elongation factor complex
.centrosome
.nucleoplasm
83 EBI-618309,EBI-10236940 INPP5J  
  .phosphatidylinositol dephosphorylation
.small molecule metabolic process
.inositol phosphate metabolic process
  + 5 more...
.inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity
.inositol-1,4,5-trisphosphate 5-phosphatase activity
.phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity
.inositol-polyphosphate 5-phosphatase activity
.dendritic shaft
.growth cone
.plasma membrane
  + 3 more...
84 EBI-618309,EBI-2555767 ZNF124  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
85 EBI-618309,EBI-602382 PKN1  
  .regulation of cell motility
.histone H3-T11 phosphorylation
.epithelial cell migration
  + 7 more...
.androgen receptor binding
.Rac GTPase binding
.histone deacetylase binding
  + 10 more...
.cleavage furrow
.midbody
.cytoplasmic membrane-bounded vesicle
  + 6 more...
86 EBI-618309,EBI-10239122 CSPP1  
  .positive regulation of cell division
.positive regulation of cytokinesis
.N/A .microtubule
.spindle
.centrosome
  + 3 more...
87 EBI-618309,EBI-2866142 FAM214A  
  .N/A .N/A .N/A
88 EBI-618309,EBI-739879 ALS2CR11  
  .N/A .N/A .N/A
89 EBI-618309,EBI-10244848 SNAP47  
  .long-term synaptic potentiation
.synaptic vesicle fusion to presynaptic membrane
.synaptic vesicle priming
.syntaxin binding
.SNAP receptor activity
.perinuclear region of cytoplasm
.neuronal cell body
.SNARE complex
  + 3 more...
90 EBI-618309,EBI-10188326 KIAA1217  
  .embryonic skeletal system development .N/A .cytoplasm
91 EBI-618309,EBI-10246152 SYT6  
  .acrosomal vesicle exocytosis
.calcium ion-dependent exocytosis of neurotransmitter
.regulation of calcium ion-dependent exocytosis
  + 2 more...
.protein homodimerization activity
.clathrin binding
.syntaxin binding
.calcium ion binding
.perinuclear endoplasmic reticulum
.synaptic vesicle membrane
.cell junction
  + 4 more...
92 EBI-618309,EBI-2130181 UBE2U  
  .proteasome-mediated ubiquitin-dependent protein catabolic process
.histone ubiquitination
.DNA repair
.protein polyubiquitination
.ubiquitin protein ligase activity
.ubiquitin protein ligase binding
.ubiquitin-like protein transferase activity
  + 2 more...
.HULC complex
.cytoplasm
.nuclear chromatin
93 EBI-618309,EBI-6447954 TTC23  
  .N/A .N/A .N/A
94 EBI-618309,EBI-10248548 RNF213  
  .protein autoubiquitination
.protein ubiquitination
.ATPase activity
.ligase activity
.zinc ion binding
.ubiquitin-protein transferase activity
.membrane
.cytoplasm
.nucleolus
95 EBI-618309,EBI-2556193 KANK2  
  .negative regulation of G1/S transition of mitotic cell cycle
.negative regulation of vitamin D receptor signaling pathway
.negative regulation of programmed cell death
  + 5 more...
.N/A .mitochondrion
.cytoplasm
96 EBI-618309,EBI-744761 CYB5R2  
  .oxidation-reduction process
.sterol biosynthetic process
.cytochrome-b5 reductase activity, acting on NAD(P)H .membrane
.mitochondrion
.nucleus
97 EBI-618309,EBI-10250303 CENPP  
  .CENP-A containing nucleosome assembly
.small GTPase mediated signal transduction
.nucleosome assembly
.mitotic cell cycle
.N/A .cytosol
.nucleoplasm
.chromosome, centromeric region
98 EBI-618309,EBI-6873045 CCDC70  
  .N/A .N/A .plasma membrane
.extracellular region
99 EBI-618309,EBI-10251462 ZNF774  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
100 EBI-618309,EBI-2557469 PPP1R18  
  .N/A .N/A .cytoskeleton
.cytoplasm
101 EBI-618309,EBI-930143 CDC73  
  .negative regulation of G1/S transition of mitotic cell cycle
.cellular response to lipopolysaccharide
.negative regulation of epithelial cell proliferation
  + 17 more...
.RNA polymerase II core binding .Cdc73/Paf1 complex
.nucleoplasm
.nucleus
102 EBI-618309,EBI-10252703 MTFR2  
  .aerobic respiration
.mitochondrion organization
.mitochondrial fission
.N/A .mitochondrion
103 EBI-618309,EBI-9675802 MORN3  
  .N/A .N/A .nucleus
104 EBI-618309,EBI-1021914 FIP1L1  
  .mRNA processing .poly(A) RNA binding .mRNA cleavage and polyadenylation specificity factor complex
.nucleoplasm
105 EBI-618309,EBI-7236323 ZFP2  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.nucleus
106 EBI-618309,EBI-10256202 RSRC2  
  .N/A .poly(A) RNA binding .N/A
107 EBI-618309,EBI-10233517 MCM10  
  .cell proliferation
.DNA replication initiation
.DNA replication
  + 2 more...
.metal ion binding
.identical protein binding
.single-stranded DNA binding
  + 2 more...
.replication fork protection complex
.cytoplasm
.nucleolus
  + 2 more...
108 EBI-618309,EBI-10256685 PID1  
  .negative regulation of glucose import in response to insulin stimulus
.positive regulation of ATP biosynthetic process
.negative regulation of ATP biosynthetic process
  + 19 more...
.N/A .cytoplasm
.nucleoplasm
109 EBI-618309,EBI-10257016 ZNF572  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
110 EBI-618309,EBI-10257651 LIMS2  
  .positive regulation of integrin-mediated signaling pathway
.negative regulation of hepatocyte proliferation
.negative regulation of neural precursor cell proliferation
  + 4 more...
.zinc ion binding .focal adhesion
.plasma membrane
.cytosol
.nucleus
111 EBI-618309,EBI-2562092 PATL1  
  .exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
.cytoplasmic mRNA processing body assembly
.gene expression
  + 2 more...
.poly(A) RNA binding
.poly(G) binding
.poly(U) RNA binding
.RNA binding
.intracellular membrane-bounded organelle
.nuclear speck
.PML body
  + 2 more...
112 EBI-618309,EBI-740376 DTX2  
  .protein ubiquitination
.Notch signaling pathway
.ligase activity
.zinc ion binding
.nuclear membrane
.cytoplasm
.nucleoplasm
113 EBI-618309,EBI-720304 ZNF410  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
114 EBI-618309,EBI-10260504 CDC20B  
  .N/A .N/A .N/A
115 EBI-618309,EBI-6658203 FAM90A1  
  .N/A .zinc ion binding
.nucleic acid binding
.N/A
116 EBI-618309,EBI-9916363 RNF135  
  .regulation of innate immune response
.innate immune response
.positive regulation of interferon-beta production
  + 2 more...
.ribonucleoprotein complex binding
.ligase activity
.zinc ion binding
.ubiquitin-protein transferase activity
.cytosol
.cytoplasm
117 EBI-618309,EBI-524753 ZDHHC17  
  .positive regulation of I-kappaB kinase/NF-kappaB signaling
.lipoprotein transport
.protein palmitoylation
  + 2 more...
.identical protein binding
.protein-cysteine S-palmitoyltransferase activity
.palmitoyltransferase activity
  + 3 more...
.intracellular membrane-bounded organelle
.Golgi-associated vesicle membrane
.integral component of membrane
  + 3 more...
118 EBI-618309,EBI-748515 GLYCTK  
  .protein phosphorylation .glycerate kinase activity
.ATP binding
.mitochondrion
.cytoplasm
119 EBI-618309,EBI-3919850 CDKL3  
  .dendrite extension
.positive regulation of dendrite morphogenesis
.negative regulation of axon extension
.cellular protein modification process
.ATP binding
.cyclin-dependent protein serine/threonine kinase activity
.protein kinase activity
.cytoplasm
.nucleus
120 EBI-618309,EBI-356265 CCAR1  
  .gene expression
.RNA splicing
.cell cycle
  + 4 more...
.poly(A) RNA binding
.ligand-dependent nuclear receptor transcription coactivator activity
.perinuclear region of cytoplasm
.nucleoplasm
121 EBI-618309,EBI-8634060 MSRB3  
  .protein repair
.response to oxidative stress
.peptide-methionine (R)-S-oxide reductase activity
.zinc ion binding
.endoplasmic reticulum
.mitochondrion
122 EBI-618309,EBI-8787606 FAM126B  
  .N/A .N/A .intracellular
123 EBI-618309,EBI-744203 IFT20  
  .regulation of autophagic vacuole assembly
.regulation of cilium assembly
.protein localization to cilium
  + 13 more...
.N/A .ciliary base
.ciliary tip
.primary cilium
  + 13 more...
124 EBI-618309,EBI-10247802 CCDC146  
  .N/A .N/A .centriole
125 EBI-618309,EBI-1104570 CEP57L1  
  .microtubule anchoring .N/A .microtubule
.microtubule organizing center
.cytoplasm
126 EBI-618309,EBI-10265323 RIBC1  
  .N/A .N/A .N/A
127 EBI-618309,EBI-3439227 ZGPAT  
  .negative regulation of transcription, DNA-templated
.negative regulation of epidermal growth factor-activated receptor activity
.negative regulation of transcription from RNA polymerase II promoter
.metal ion binding
.sequence-specific DNA binding
.sequence-specific DNA binding transcription factor activity
  + 2 more...
.nucleus
128 EBI-618309,EBI-2851213 TTC9C  
  .N/A .N/A .N/A
129 EBI-618309,EBI-954696 TCEANC  
  .regulation of DNA-templated transcription, elongation
.regulation of transcription from RNA polymerase II promoter
.transcription, DNA-templated
.DNA binding .nucleus
130 EBI-618309,EBI-10268935 C12orf50  
  .N/A .N/A .N/A
131 EBI-618309,EBI-10269342 CCDC150  
  .N/A .N/A .N/A
132 EBI-618309,EBI-10270867 ATP6V1C2  
  .phagosome maturation
.transmembrane transport
.interaction with host
  + 6 more...
.protein dimerization activity
.hydrogen-exporting ATPase activity, phosphorylative mechanism
.extracellular exosome
.proton-transporting V-type ATPase, V1 domain
.cytosol
.lysosomal membrane
133 EBI-618309,EBI-7067260 SPATA22  
  .reproductive system development
.regulation of meiotic cell cycle
.fertilization
  + 3 more...
.N/A .chromosome
134 EBI-618309,EBI-740727 ZNF417  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
135 EBI-618309,EBI-742750 BAHD1  
  .negative regulation of transcription, DNA-templated
.heterochromatin assembly
.transcription, DNA-templated
.chromatin silencing
.chromatin binding
.transcription regulatory region sequence-specific DNA binding
.chromatin silencing complex
.nucleoplasm
.chromatin
136 EBI-618309,EBI-10175300 CCHCR1  
  .cell differentiation
.multicellular organismal development
.protein export from nucleus
.N/A .centriole
.cytoplasm
.nucleus
137 EBI-618309,EBI-10244131 FBF1  
  .establishment of epithelial cell polarity
.apical junction assembly
.cilium assembly
.organelle organization
.N/A .ciliary transition fiber
.cell junction
.cytosol
  + 3 more...
138 EBI-618309,EBI-5542466 RAB2B  
  .positive regulation of exocytosis
.Rab protein signal transduction
.vesicle-mediated transport
  + 2 more...
.GTP binding
.GTPase activity
.extracellular exosome
.plasma membrane
.endoplasmic reticulum membrane
.Golgi membrane
139 EBI-618309,EBI-923440 GATAD2B  
  .ATP-dependent chromatin remodeling
.transcription, DNA-templated
.sequence-specific DNA binding
.zinc ion binding
.sequence-specific DNA binding transcription factor activity
.protein complex
.nuclear speck
.nucleoplasm
.nuclear chromatin
140 EBI-618309,EBI-79084 SHC3  
  .neurotrophin TRK receptor signaling pathway
.synaptic transmission, glutamatergic
.insulin receptor signaling pathway
  + 5 more...
.receptor tyrosine kinase binding
.protein kinase binding
.signal transducer activity
.plasma membrane
.cytosol
141 EBI-618309,EBI-746309 GPKOW  
  .N/A .nucleic acid binding .nucleoplasm
142 EBI-618309,EBI-399080 KAT5  
  .positive regulation of protein acetylation
.cellular response to estradiol stimulus
.positive regulation of transcription from RNA polymerase II promoter
  + 14 more...
.repressing transcription factor binding
.androgen receptor binding
.metal ion binding
  + 2 more...
.perinuclear region of cytoplasm
.NuA4 histone acetyltransferase complex
.Piccolo NuA4 histone acetyltransferase complex
  + 6 more...
143 EBI-618309,EBI-1057139 CUL5  
  .intrinsic apoptotic signaling pathway
.calcium ion transmembrane transport
.cytosolic calcium ion homeostasis
  + 7 more...
.ubiquitin protein ligase binding
.calcium channel activity
.receptor activity
.Cul5-RING ubiquitin ligase complex
.plasma membrane
.cytosol
.nucleus
144 EBI-618309,EBI-455078 SMARCE1  
  .negative regulation of transcription, DNA-templated
.ATP-dependent chromatin remodeling
.metabolic process
  + 4 more...
.protein N-terminus binding
.ligand-dependent nuclear receptor binding
.N-acetyltransferase activity
  + 4 more...
.nBAF complex
.npBAF complex
.protein complex
  + 6 more...
145 EBI-618309,EBI-746778 MAGOHB  
  .mRNA transport
.RNA splicing
.mRNA processing
.poly(A) RNA binding .catalytic step 2 spliceosome
.exon-exon junction complex
146 EBI-618309,EBI-726510 LENG1  
  .N/A .N/A .N/A
147 EBI-618309,EBI-746252 GCC1  
  .protein targeting to Golgi .N/A .plasma membrane
.Golgi apparatus
.cytoplasm
.Golgi membrane
148 EBI-618309,EBI-2514791 HAUS1  
  .cell division
.centrosome organization
.spindle assembly
.mitotic nuclear division
.N/A .HAUS complex
.microtubule
.centrosome
  + 2 more...
149 EBI-618309,EBI-9089467 RAB39B  
  .synapse organization
.Rab protein signal transduction
.vesicle-mediated transport
  + 2 more...
.myosin V binding
.GTP binding
.GTPase activity
.neuron projection
.vesicle
.plasma membrane
  + 2 more...
150 EBI-618309,EBI-719955 LINGO1  
  .negative regulation of axonogenesis
.regulation of axonogenesis
.negative regulation of oligodendrocyte differentiation
  + 4 more...
.N/A .integral component of membrane
.plasma membrane
151 EBI-618309,EBI-745021 STAMBPL1  
  .N/A .metal ion binding
.metallopeptidase activity
.membrane
152 EBI-618309,EBI-747719 SNF8  
  .regulation of viral budding via host ESCRT complex
.positive regulation of exosomal secretion
.regulation of protein complex stability
  + 11 more...
.protein N-terminus binding
.protein homodimerization activity
.channel regulator activity
  + 2 more...
.extracellular exosome
.recycling endosome
.perinuclear region of cytoplasm
  + 10 more...
153 EBI-618309,EBI-741158 WDYHV1  
  .cellular protein modification process .protein-N-terminal glutamine amidohydrolase activity .cytosol
.nucleus
154 EBI-618309,EBI-740272 RBM17  
  .alternative mRNA splicing, via spliceosome .RNA binding
.nucleotide binding
.spliceosomal complex
.nucleoplasm
155 EBI-618309,EBI-744257 ZNF414  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
156 EBI-618309,EBI-744859 ANKRD36BP1  
  .N/A .N/A .N/A
157 EBI-618309,EBI-740773 RBM41  
  .N/A .RNA binding
.nucleotide binding
.N/A
158 EBI-618309,EBI-8833163 LCOR  
  .transcription from RNA polymerase II promoter
.negative regulation of transcription from RNA polymerase II promoter
.sequence-specific DNA binding transcription factor activity
.DNA binding
.nucleus
159 EBI-618309,EBI-2836148 RITA1  
  .nuclear export
.negative regulation of Notch signaling pathway
.neurogenesis
  + 2 more...
.tubulin binding .centrosome
.Golgi apparatus
.cytoplasm
  + 2 more...
160 EBI-618309,EBI-10290304 HRASLS5  
  .N/A .transferase activity, transferring acyl groups .N/A
161 EBI-618309,EBI-719840 CCDC17  
  .N/A .N/A .N/A
162 EBI-618309,EBI-720016 HYLS1  
  .N/A .N/A .plasma membrane
.centrosome
.cytoplasm
.nucleus
163 EBI-618309,EBI-948288 ZNF488  
  .positive regulation of oligodendrocyte differentiation
.negative regulation of transcription, DNA-templated
.oligodendrocyte development
  + 2 more...
.metal ion binding
.DNA binding
.sequence-specific DNA binding RNA polymerase II transcription factor activity
.nucleus
164 EBI-618309,EBI-2682299 ZMAT2  
  .N/A .zinc ion binding
.DNA binding
.nucleus
165 EBI-618309,EBI-1046387 TTC25  
  .N/A .N/A .cytoplasm
166 EBI-618309,EBI-3918381 TSSK3  
  .intracellular signal transduction
.cell differentiation
.regulation of signal transduction
  + 3 more...
.ATP binding
.protein serine/threonine kinase activity
.magnesium ion binding
.cytoplasm
.nucleus
167 EBI-618309,EBI-10292648 FAM193B  
  .N/A .N/A .cytoplasm
.nucleolus
.nucleoplasm
.nucleus
168 EBI-618309,EBI-6658697 ALKBH3  
  .oxidative single-stranded DNA demethylation
.cell proliferation
.DNA dealkylation involved in DNA repair
.DNA repair
.cytosine C-5 DNA demethylase activity
.DNA-N1-methyladenine dioxygenase activity
.L-ascorbic acid binding
.ferrous iron binding
.mitochondrion
.cytoplasm
.nucleoplasm
.nucleus
169 EBI-618309,EBI-10293291 LYSMD1  
  .N/A .N/A .N/A
170 EBI-618309,EBI-6427977 ZNF587  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
171 EBI-618309,EBI-954116 SECISBP2  
  .negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
.selenocysteine incorporation
.poly(A) RNA binding
.ribonucleoprotein complex binding
.selenocysteine insertion sequence binding
.mRNA 3'-UTR binding
.ribonucleoprotein complex
.mitochondrion
.nucleoplasm
172 EBI-618309,EBI-10293968 PPP1R16B  
  .positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis
.negative regulation of peptidyl-serine dephosphorylation
.establishment of endothelial barrier
  + 6 more...
.protein phosphatase type 1 regulator activity .perinuclear region of cytoplasm
.cell projection
.plasma membrane
.nucleus
173 EBI-618309,EBI-374880 CDC5L  
  .signal transduction involved in DNA damage checkpoint
.gene expression
.RNA splicing
  + 4 more...
.WD40-repeat domain binding
.poly(A) RNA binding
.chromatin binding
.DNA binding
.catalytic step 2 spliceosome
.nuclear speck
.membrane
  + 5 more...
174 EBI-618309,EBI-726447 PKP4  
  .positive regulation of GTPase activity
.positive regulation of cytokinesis
.regulation of cell adhesion
  + 3 more...
.N/A .mitotic spindle
.spindle midzone
.perinuclear region of cytoplasm
  + 9 more...
175 EBI-618309,EBI-473181 BARD1  
  .protein K6-linked ubiquitination
.negative regulation of protein export from nucleus
.positive regulation of protein catabolic process
  + 9 more...
.protein heterodimerization activity
.protein homodimerization activity
.kinase binding
  + 4 more...
.BRCA1-A complex
.intracellular membrane-bounded organelle
.BRCA1-BARD1 complex
  + 5 more...
176 EBI-618309,EBI-1048311 AKAP9  
  .positive regulation of potassium ion transmembrane transporter activity
.regulation of heart rate by cardiac conduction
.cellular response to cAMP
  + 11 more...
.ion channel binding
.protein complex scaffold
.potassium channel regulator activity
.receptor binding
.intracellular membrane-bounded organelle
.ciliary basal body
.voltage-gated potassium channel complex
  + 5 more...
177 EBI-618309,EBI-1752811 FAM110A  
  .N/A .N/A .microtubule organizing center
.cytoplasm
.spindle pole
178 EBI-618309,EBI-9658624 RHNO1  
  .cellular response to ionizing radiation
.positive regulation of G0 to G1 transition
.cellular response to UV
  + 2 more...
.N/A .chromosome
.nucleus
179 EBI-618309,EBI-741350 THAP7  
  .negative regulation of transcription, DNA-templated
.transcription, DNA-templated
.C2H2 zinc finger domain binding
.protein N-terminus binding
.metal ion binding
.DNA binding
.nuclear speck
.chromosome
180 EBI-618309,EBI-742459 MMTAG2  
  .N/A .poly(A) RNA binding .N/A
181 EBI-618309,EBI-2125614 KIFC3  
  .epithelial cell-cell adhesion
.zonula adherens maintenance
.metabolic process
  + 3 more...
.ATPase activity
.ATP binding
.microtubule motor activity
.extracellular exosome
.cytoplasmic vesicle membrane
.zonula adherens
  + 4 more...
182 EBI-618309,EBI-744935 C20orf195  
  .N/A .N/A .extracellular exosome
183 EBI-618309,EBI-739784 CINP  
  .cell division
.cell cycle
.DNA repair
.DNA replication
.N/A .nucleus
184 EBI-618309,EBI-747093 IFT27  
  .intraciliary transport
.Rab protein signal transduction
.metabolic process
  + 3 more...
.GTP binding
.GTPase activity
.ciliary tip
.sperm principal piece
.sperm midpiece
  + 6 more...
185 EBI-618309,EBI-10300345 CCDC94  
  .N/A .N/A .N/A
186 EBI-618309,EBI-748391 SCNM1  
  .RNA splicing
.mRNA processing
.metal ion binding
.enzyme binding
.nuclear speck
.nucleolus
.nucleus
187 EBI-618309,EBI-295391 PARD6B  
  .tight junction assembly
.cell division
.cell-cell junction organization
  + 7 more...
.N/A .extracellular exosome
.apical part of cell
.protein complex
  + 6 more...
188 EBI-618309,EBI-928842 NDEL1  
  .neuron projection extension
.neurofilament cytoskeleton organization
.centrosome localization
  + 20 more...
.oligopeptidase activity
.microtubule binding
.neurofilament cytoskeleton
.axon hillock
.cell leading edge
  + 10 more...
189 EBI-618309,EBI-1047335 ISCU  
  .protein maturation by iron-sulfur cluster transfer
.[2Fe-2S] cluster assembly
.small molecule metabolic process
  + 3 more...
.4 iron, 4 sulfur cluster binding
.2 iron, 2 sulfur cluster binding
.iron-sulfur transferase activity
  + 3 more...
.cytosol
.mitochondrial matrix
.mitochondrion
  + 2 more...
190 EBI-618309,EBI-741626 FAM124B  
  .N/A .N/A .N/A
191 EBI-618309,EBI-747035 SH2D4A  
  .negative regulation of phosphatase activity .phosphatase binding .cytoplasm
192 EBI-618309,EBI-739467 GORASP2  
  .organelle organization
.mitotic cell cycle
.N/A .membrane
.Golgi apparatus
.Golgi membrane
193 EBI-618309,EBI-712912 CBX8  
  .cellular protein metabolic process
.post-translational protein modification
.protein sumoylation
  + 3 more...
.methylated histone binding
.ubiquitin-protein transferase activity
.single-stranded RNA binding
.PRC1 complex
.PcG protein complex
.nucleoplasm
  + 3 more...
194 EBI-618309,EBI-752122 NXT2  
  .mRNA transport
.protein transport
.N/A .cytoplasm
.nucleus
195 EBI-618309,EBI-371876 EXOSC5  
  .RNA phosphodiester bond hydrolysis, exonucleolytic
.polyadenylation-dependent snoRNA 3'-end processing
.nuclear mRNA surveillance
  + 10 more...
.RNA binding
.3'-5'-exoribonuclease activity
.transcriptionally active chromatin
.cytosol
.cytoplasm
  + 5 more...
196 EBI-618309,EBI-5457304 FAM207A  
  .N/A .N/A .N/A
197 EBI-618309,EBI-749261 CCDC87  
  .cytokinesis
.microtubule cytoskeleton organization
.N/A .N/A
198 EBI-618309,EBI-740282 FBXO28  
  .N/A .N/A .N/A
199 EBI-618309,EBI-8643161 C1orf109  
  .N/A .N/A .N/A
200 EBI-618309,EBI-743375 CHCHD3  
  .mitochondrial fusion
.inner mitochondrial membrane organization
.negative regulation of transcription from RNA polymerase II promoter
.protein complex scaffold
.phosphatase binding
.RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
.extracellular exosome
.mitochondrial inner membrane
.mitochondrion
  + 2 more...
201 EBI-618309,EBI-745520 ZNF581  
  .transcription from RNA polymerase II promoter
.regulation of transcription from RNA polymerase II promoter
.metal ion binding
.RNA polymerase II regulatory region sequence-specific DNA binding
.nucleus
202 EBI-618309,EBI-743428 RCOR3  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.chromatin binding
.DNA binding
.nucleus
203 EBI-618309,EBI-10318831 MYEF2  
  .neuron differentiation
.myotube differentiation
.transcription, DNA-templated
.poly(A) RNA binding
.DNA binding
.nucleotide binding
.cytoplasm
.nucleoplasm
.nucleus
204 EBI-618309,EBI-399246 MORF4L1  
  .histone H2A acetylation
.histone H4 acetylation
.regulation of growth
  + 6 more...
.protein N-terminus binding
.chromatin binding
.NuA4 histone acetyltransferase complex
.Sin3 complex
.nucleoplasm
205 EBI-618309,EBI-77321 DAXX  
  .positive regulation of apoptotic signaling pathway
.positive regulation of neuron death
.negative regulation of transcription, DNA-templated
  + 13 more...
.androgen receptor binding
.protein N-terminus binding
.protein homodimerization activity
  + 10 more...
.SWI/SNF superfamily-type complex
.PML body
.cytosol
  + 5 more...
206 EBI-618309,EBI-395282 AFF4  
  .spermatid development
.transcription from RNA polymerase II promoter
.sequence-specific DNA binding transcription factor activity .transcriptionally active chromatin
.transcription elongation factor complex
.mitochondrion
  + 3 more...
207 EBI-618309,EBI-748350 RTDR1  
  .N/A .N/A .N/A
208 EBI-618309,EBI-751683 SAP30BP  
  .negative regulation of gene expression, epigenetic
.regulation of gene expression, epigenetic
.positive regulation of cell death
  + 4 more...
.N/A .intermediate filament cytoskeleton
.nucleoplasm
.nucleus
209 EBI-618309,EBI-10172526 MID2  
  .negative regulation of viral release from host cell
.positive regulation of NF-kappaB transcription factor activity
.positive regulation of sequence-specific DNA binding transcription factor activity
  + 6 more...
.phosphoprotein binding
.protein heterodimerization activity
.protein homodimerization activity
  + 3 more...
.extracellular exosome
.microtubule
.cytoplasm
210 EBI-618309,EBI-2134033 DCTN4  
  .antigen processing and presentation of exogenous peptide antigen via MHC class II
.nuclear migration
.protein N-terminus binding .dynactin complex
.cytoplasmic dynein complex
.cytosol
  + 3 more...
211 EBI-618309,EBI-744066 SPATA2  
  .cell differentiation
.spermatogenesis
.multicellular organismal development
.N/A .cytoplasm
.nucleolus
.nucleus
212 EBI-618309,EBI-7954236 SCAF8  
  .RNA splicing
.mRNA processing
.RNA polymerase core enzyme binding
.RNA binding
.nucleotide binding
.nuclear matrix
.spliceosomal complex
.nucleoplasm
213 EBI-618309,EBI-1047497 SAMD4A  
  .positive regulation of translation
.negative regulation of translation
.poly(A) RNA binding
.translation repressor activity
.synapse
.dendrite
.cell junction
.cytoplasm
214 EBI-618309,EBI-742802 FAM50B  
  .N/A .N/A .nucleus
215 EBI-618309,EBI-10187270 AMOTL2  
  .hippo signaling
.Wnt signaling pathway
.N/A .recycling endosome
.cytoplasmic vesicle
.apical plasma membrane
  + 2 more...
216 EBI-618309,EBI-712969 CCDC53  
  .protein transport .N/A .WASH complex
.intracellular membrane-bounded organelle
.actin cytoskeleton
.early endosome
217 EBI-618309,EBI-6659161 MAB21L2  
  .camera-type eye development
.embryonic body morphogenesis
.positive regulation of cell proliferation
  + 2 more...
.N/A .nucleus
218 EBI-618309,EBI-744782 NME7  
  .left/right pattern formation
.ciliary receptor clustering involved in smoothened signaling pathway
.intraciliary transport
  + 6 more...
.metal ion binding
.ATP binding
.nucleoside diphosphate kinase activity
.ciliary basal body
.centrosome
219 EBI-618309,EBI-717229 TSSC4  
  .N/A .N/A .N/A
220 EBI-618309,EBI-2321769 CHCHD2  
  .regulation of cellular response to hypoxia
.positive regulation of transcription from RNA polymerase II promoter
.transcription, DNA-templated
.sequence-specific DNA binding
.transcription factor binding
.mitochondrion
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
adrenal gland30
blood40
bone97
brain23
cervix20
connective tissue60
ear62
embryonic tissue46
esophagus49
eye47
heart78
intestine94
kidney71
larynx42
liver160
lung53
lymph node33
mammary gland85
muscle47
nerve64
ovary88
pancreas107
parathyroid194
pituitary gland60
placenta42
prostate89
skin75
stomach31
testis16
thyroid85
trachea19
uterus17
Health State
TissuesTPM*
normal51
breast (mammary gland) tumor75
cervical tumor28
chondrosarcoma84
colorectal tumor133
esophageal tumor57
gastrointestinal tumor25
germ cell tumor26
glioma93
head and neck tumor29
kidney tumor116
leukemia42
liver tumor10
lung tumor87
lymphoma13
non-neoplasia10
ovarian tumor105
pancreatic tumor66
primitive neuroectodermal tumor of the CNS62
prostate cancer48
retinoblastoma43
skin tumor95
soft tissue/muscle tissue tumor39
uterine tumor11
Developmental Stage
TissuesTPM*
adult58
embryoid body71
blastocyst16
fetus50
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue35.1
adrenal gland38
appendix34.8
bone marrow20.2
cerebral cortex27.6
colon33
duodenum27.8
esophagus45.7
gallbladder42
heart muscle43.5
kidney29.2
liver19.8
lung38
lymph node23.2
ovary48.3
pancreas29.9
placenta49.1
prostate51.6
salivary gland45
skin44.4
small intestine29.7
spleen24.5
stomach43.7
testis31.5
thyroid gland49.4
urinary bladder38.4
Tissues
TissuesExpression level
adrenal glandMedium
appendixMedium
bone marrowMedium
breastMedium
bronchusMedium
cerebellumMedium
cerebral cortexHigh
cervix, uterineMedium
colonMedium
duodenumMedium
endometrium 1Medium
endometrium 2Medium
epididymisMedium
esophagusMedium
fallopian tubeMedium
gallbladderHigh
heart muscleMedium
hippocampusHigh
kidneyMedium
lateral ventricleMedium
liverLow
lungMedium
lymph nodeMedium
nasopharynxLow
oral mucosaMedium
pancreasMedium
parathyroid glandMedium
placentaHigh
prostateMedium
rectumMedium
salivary glandHigh
seminal vesicleMedium
skin 1Medium
skin 2Low
small intestineHigh
smooth muscleLow
soft tissue 1Medium
spleenLow
stomach 1Medium
stomach 2Medium
testisMedium
thyroid glandMedium
tonsilHigh
urinary bladderMedium
vaginaLow
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*602580, gene) Golgi autoantigen, golgin subfamily a, 2; GOLGA2OMIM


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