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> Protein (NX_Q08AE8)
Protein (NX_Q08AE8)
Protein
Gene SymbolSPIRE1 to neXtProt (NX_Q08AE8)
DescriptionProtein spire homolog 1
Chromosome18
Location18p11.21 (12446511 ~ 12658133) to Ensembl
Sequene Features : Isoforms 5, Variants 63, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.formin-nucleated actin cable assembly
.establishment of meiotic spindle localization
.Golgi vesicle transport
  + 7 more...
.N/A .perinuclear region of cytoplasm
.cytoplasmic vesicle membrane
.cell cortex
  + 3 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
5 63 6
2014-09-19protein level
5 53 6
2014-05-27protein level
5 53 6
2014-02-25protein level
4 52 6
2013-12-09protein level
4 43 6
2013-11-01protein level
4 42 6
2013-09-12protein level
4 42 5
2013-08-17protein level
4 42 5
2013-07-15protein level
4 28 5
2013-06-11protein level
4 28 5
2013-02-12protein level
4 8 12
2012-12-20protein level
4 8 12
2012-10-30protein level
4 7 12
2012-10-07protein level
4 7 3
2012-08-24protein level
4 4 3
2012-07-28protein level
4 4 3
2012-06-08protein level
4 2 3
2012-05-07protein level
4 2 3
2012-04-10protein level
4 2 3
2012-01-13protein level
4 2 3
2011-12-20protein level
4 3 3
2011-11-11protein level
4 3 3
2011-08-23protein level
4 3 3
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q08AE8-1
1 31 0 85489.1685
NX_Q08AE8-2
0 32 0 83903.4458
NX_Q08AE8-3
0 25 0 67014.0569
NX_Q08AE8-4
1 18 0 52713.7663
NX_Q08AE8-5
1 25 0 71522.348
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland91
blood8
bone111
bone marrow20
brain43
cervix61
connective tissue26
ear310
embryonic tissue14
esophagus49
eye52
heart11
intestine8
kidney37
liver34
lung143
mammary gland39
mouth15
muscle47
nerve64
ovary39
pancreas79
parathyroid145
placenta45
prostate10
salivary gland49
skin23
stomach31
testis101
thyroid42
trachea115
uterus17
vascular38
Health State
TissuesTPM*
normal54
adrenal tumor79
breast (mammary gland) tumor53
cervical tumor57
chondrosarcoma96
colorectal tumor8
esophageal tumor57
gastrointestinal tumor8
germ cell tumor11
glioma55
head and neck tumor29
kidney tumor14
leukemia42
liver tumor31
lung tumor311
non-neoplasia20
ovarian tumor39
pancreatic tumor28
prostate cancer9
retinoblastoma64
skin tumor7
soft tissue/muscle tissue tumor23
Developmental Stage
TissuesTPM*
adult60
embryoid body14
blastocyst32
neonate32
fetus64
infant42
juvenile35
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue7.3
adrenal gland23.1
appendix4.6
cerebral cortex34.4
colon4.1
duodenum2.1
esophagus9.7
gallbladder10.4
heart muscle17.7
kidney14.9
liver5.1
lung13.6
lymph node3.2
ovary9
pancreas3.4
placenta5.8
prostate10.9
salivary gland9.8
skin6
small intestine3.1
spleen5.3
stomach7.3
testis36.8
thyroid gland25.7
urinary bladder11
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*609216, gene) Spire, drosophila, homolog of, 1; SPIRE1OMIM


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