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> Protein (NX_Q12789)
Protein (NX_Q12789)
Protein
Gene SymbolGTF3C1 to neXtProt (NX_Q12789)
DescriptionGeneral transcription factor 3C polypeptide 1
Chromosome16
Location16p12.1 (27470876 ~ 27561234) to Ensembl
Sequene Features : Isoforms 2, Variants 249, PTMs 29 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.tRNA transcription from RNA polymerase III promoter
.5S class rRNA transcription from RNA polymerase III type 1 promoter
.gene expression
  + 4 more...
.DNA binding .ribonucleoprotein complex
.membrane
.nucleolus
  + 3 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 249 29
2014-09-19protein level
2 177 29
2014-05-27protein level
2 177 30
2014-02-25protein level
2 178 30
2013-12-09protein level
2 150 30
2013-11-01protein level
2 146 28
2013-09-12protein level
2 146 27
2013-08-17protein level
2 146 27
2013-07-15protein level
2 91 19
2013-06-11protein level
2 91 19
2013-02-12protein level
2 39 34
2012-12-20protein level
2 40 34
2012-10-30protein level
2 48 34
2012-10-07protein level
2 48 17
2012-08-24protein level
2 33 17
2012-07-28protein level
2 33 17
2012-06-08protein level
2 42 17
2012-05-07protein level
2 42 17
2012-04-10protein level
2 42 17
2012-01-13protein level
2 24 17
2011-12-20protein level
2 24 17
2011-11-11protein level
2 24 16
2011-08-23protein level
2 24 16
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q12789-2
2 95 0 238723.8424
NX_Q12789-3
1 95 0 236128.7021
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-357956,EBI-741181 AGTRAP  
  .regulation of blood pressure
.response to hypoxia
.angiotensin type II receptor activity .intracellular membrane-bounded organelle
.cytoplasmic vesicle membrane
.integral component of membrane
  + 6 more...
2 EBI-357956,EBI-2548702 CMTM5  
  .negative regulation of myoblast differentiation
.chemotaxis
.N/A .integral component of membrane
.extracellular space
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
ascites25
blood57
bone27
bone marrow102
brain63
cervix103
connective tissue26
embryonic tissue126
eye114
intestine125
kidney56
larynx127
liver73
lung101
lymph225
lymph node77
mammary gland52
mouth136
muscle131
nerve128
ovary128
pancreas79
pituitary gland121
placenta56
prostate84
skin109
spleen93
stomach31
testis66
thymus150
thyroid279
trachea57
umbilical cord145
uterus90
vascular38
Health State
TissuesTPM*
normal57
breast (mammary gland) tumor64
cervical tumor144
chondrosarcoma60
colorectal tumor186
gastrointestinal tumor75
germ cell tumor125
glioma74
head and neck tumor149
kidney tumor116
leukemia42
liver tumor135
lung tumor233
lymphoma193
non-neoplasia20
ovarian tumor52
pancreatic tumor114
primitive neuroectodermal tumor of the CNS133
prostate cancer86
retinoblastoma150
skin tumor135
soft tissue/muscle tissue tumor39
uterine tumor88
Developmental Stage
TissuesTPM*
adult67
embryoid body100
blastocyst244
fetus35
infant42
juvenile143
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue12.9
adrenal gland20.9
appendix15.6
bone marrow18.5
cerebral cortex21.7
colon13.7
duodenum10.5
esophagus28
gallbladder15.8
heart muscle18.7
kidney18
liver8.9
lung17.4
lymph node16.7
ovary20.7
pancreas10.7
placenta11.2
prostate39.5
salivary gland10.9
skin43
small intestine10.4
spleen15.5
stomach16.9
testis21.5
thyroid gland33.1
urinary bladder13
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*603246, gene) General transcription factor 3c, polypeptide 1; GTF3C1OMIM


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