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> Protein (NX_Q13011)
Protein (NX_Q13011)
Protein
Gene SymbolECH1 to neXtProt (NX_Q13011)
DescriptionDelta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial
Chromosome19
Location19q13.2 (39306062 ~ 39322645) to Ensembl
Sequene Features : Isoforms 1, Variants 31, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.fatty acid beta-oxidation .isomerase activity
.receptor binding
.extracellular exosome
.membrane
.peroxisome
.mitochondrion
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 31 5
2014-09-19protein level
1 24 5
2014-05-27protein level
1 24 5
2014-02-25protein level
1 24 4
2013-12-09protein level
1 15 4
2013-11-01protein level
1 14 3
2013-09-12protein level
1 14 3
2013-08-17protein level
1 14 3
2013-07-15protein level
1 12 3
2013-06-11protein level
1 12 3
2013-02-12protein level
1 8 4
2012-12-20protein level
1 8 4
2012-10-30protein level
1 11 4
2012-10-07protein level
1 11 6
2012-08-24protein level
1 10 6
2012-07-28protein level
1 10 6
2012-06-08protein level
1 17 6
2012-05-07protein level
1 17 6
2012-04-10protein level
1 17 6
2012-01-13protein level
1 18 6
2011-12-20protein level
1 18 6
2011-11-11protein level
1 18 6
2011-08-23protein level
1 18 6
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q13011-1
17 0 0 35793.2799
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-711968,EBI-518675 STAT3  
  .negative regulation of neuron migration
.interleukin-6-mediated signaling pathway
.JAK-STAT cascade involved in growth hormone signaling pathway
  + 35 more...
.protein dimerization activity
.transcription regulatory region DNA binding
.protein phosphatase binding
  + 9 more...
.plasma membrane
.cytosol
.mitochondrial inner membrane
  + 4 more...
2 EBI-711968,EBI-466029 HTT  
  .negative regulation of extrinsic apoptotic signaling pathway
.iron ion homeostasis
.L-glutamate import
  + 38 more...
.diazepam binding
.beta-tubulin binding
.dynein intermediate chain binding
  + 6 more...
.protein complex
.cytoplasmic vesicle membrane
.dendrite
  + 11 more...
3 EBI-711968,EBI-359224 TRAF1  
  .regulation of extrinsic apoptotic signaling pathway
.positive regulation of NF-kappaB transcription factor activity
.signal transduction
  + 2 more...
.thioesterase binding
.ubiquitin protein ligase binding
.zinc ion binding
.tumor necrosis factor receptor binding
.cytoplasm
4 EBI-711968,EBI-10175124 FAM9B  
  .spermatid development .N/A .nucleoplasm
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue544
adrenal gland91
ascites125
bladder66
blood220
bone153
bone marrow184
brain96
cervix288
connective tissue33
embryonic tissue79
esophagus297
eye124
heart301
intestine237
kidney303
larynx170
liver141
lung158
lymph180
lymph node66
mammary gland251
mouth30
muscle404
nerve64
ovary305
pancreas356
parathyroid48
pharynx712
pituitary gland121
placenta144
prostate258
salivary gland394
skin180
spleen112
stomach62
testis96
thymus25
thyroid107
tonsil58
umbilical cord72
uterus301
vascular58
Health State
TissuesTPM*
normal128
adrenal tumor79
bladder carcinoma113
breast (mammary gland) tumor322
cervical tumor376
chondrosarcoma132
colorectal tumor275
esophageal tumor347
gastrointestinal tumor109
germ cell tumor53
glioma177
head and neck tumor127
kidney tumor246
leukemia201
liver tumor62
lung tumor184
lymphoma193
non-neoplasia41
ovarian tumor367
pancreatic tumor523
primitive neuroectodermal tumor of the CNS244
prostate cancer404
retinoblastoma150
skin tumor199
soft tissue/muscle tissue tumor95
uterine tumor599
Developmental Stage
TissuesTPM*
adult188
embryoid body100
blastocyst97
neonate32
fetus113
infant42
juvenile53
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue183.6
adrenal gland173
appendix80.3
bone marrow72.3
cerebral cortex57.4
colon195.6
duodenum138.7
esophagus154.6
gallbladder115.7
heart muscle295.6
kidney224.1
liver332.9
lung102
lymph node107.5
ovary99.4
pancreas75.2
placenta140.4
prostate99.4
salivary gland111.9
skin96.8
small intestine127.9
spleen151.1
stomach111.8
testis92.2
thyroid gland108
urinary bladder109.6
Tissues
TissuesExpression level
adrenal glandHigh
appendixHigh
bone marrowMedium
breastMedium
bronchusMedium
cerebellumMedium
cerebral cortexHigh
cervix, uterineMedium
colonHigh
duodenumHigh
endometrium 1High
endometrium 2High
epididymisHigh
esophagusMedium
fallopian tubeMedium
gallbladderHigh
heart muscleHigh
hippocampusHigh
kidneyHigh
lateral ventricleHigh
liverHigh
lungHigh
lymph nodeHigh
nasopharynxMedium
oral mucosaMedium
ovaryLow
pancreasHigh
parathyroid glandMedium
placentaHigh
prostateHigh
rectumHigh
salivary glandMedium
seminal vesicleMedium
skeletal muscleMedium
skin 1Medium
skin 2High
small intestineHigh
smooth muscleMedium
soft tissue 1Low
soft tissue 2Medium
spleenMedium
stomach 1Medium
stomach 2Medium
testisHigh
thyroid glandMedium
tonsilHigh
urinary bladderMedium
vaginaMedium
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*600696, gene) Enoyl-coa hydratase, peroxisomal; ECH1OMIM


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