Home| Contact Us

HOME SEARCH STATISTICS
> Protein (NX_Q13084)
Protein (NX_Q13084)
Protein
Gene SymbolMRPL28 to neXtProt (NX_Q13084)
Description39S ribosomal protein L28, mitochondrial
Chromosome16
Location16p13.3 (417384 ~ 420527) to Ensembl
Sequene Features : Isoforms 1, Variants 36, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.mitochondrial translational termination
.mitochondrial translational elongation
.mitochondrial translational initiation
  + 3 more...
.poly(A) RNA binding
.structural constituent of ribosome
.mitochondrial ribosome
.mitochondrial inner membrane
.mitochondrion
  + 2 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 36 1
2014-09-19protein level
1 28 1
2014-05-27protein level
1 28 1
2014-02-25protein level
1 28 1
2013-12-09protein level
1 20 1
2013-11-01protein level
1 20 0
2013-09-12protein level
1 20 0
2013-08-17protein level
1 20 0
2013-07-15protein level
1 17 0
2013-06-11protein level
1 17 0
2013-02-12protein level
1 14 0
2012-12-20protein level
1 13 0
2012-10-30protein level
1 14 0
2012-10-07protein level
1 14 0
2012-08-24protein level
1 13 0
2012-07-28protein level
1 13 0
2012-06-08protein level
1 16 0
2012-05-07protein level
1 16 0
2012-04-10protein level
1 16 0
2012-01-13protein level
1 13 0
2011-12-20protein level
1 13 0
2011-11-11protein level
1 13 0
2011-08-23protein level
1 13 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q13084-1
10 0 0 30137.8007
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-723426,EBI-744798 TRAF3IP2  
  .immunoglobulin secretion
.positive regulation of I-kappaB kinase/NF-kappaB signaling
.intracellular signal transduction
  + 3 more...
.N/A .N/A
2 EBI-723426,EBI-1181367 CDR2  
  .N/A .N/A .cytoplasm
3 EBI-723426,EBI-2796967 TEF  
  .rhythmic process
.positive regulation of transcription from RNA polymerase II promoter
.regulation of transcription from RNA polymerase II promoter
.transcription, DNA-templated
.sequence-specific DNA binding
.sequence-specific DNA binding transcription factor activity
.double-stranded DNA binding
.nucleus
4 EBI-723426,EBI-2549423 HMBOX1  
  .positive regulation of transcription, DNA-templated
.negative regulation of transcription, DNA-templated
.transcription, DNA-templated
.DNA binding .cytoplasm
.nucleoplasm
.nucleus
5 EBI-723426,EBI-10175124 FAM9B  
  .spermatid development .N/A .nucleoplasm
6 EBI-723426,EBI-744695 BANP  
  .negative regulation of protein catabolic process
.protein localization to nucleus
.chromatin modification
  + 4 more...
.DNA binding .nucleoplasm
7 EBI-723426,EBI-3650647 TRAF4  
  .positive regulation of protein homodimerization activity
.positive regulation of JNK cascade
.positive regulation of protein kinase activity
  + 6 more...
.WW domain binding
.thioesterase binding
.ubiquitin protein ligase binding
  + 4 more...
.perinuclear region of cytoplasm
.tight junction
.plasma membrane
  + 3 more...
8 EBI-723426,EBI-747204 IKZF3  
  .regulation of lymphocyte differentiation
.regulation of B cell differentiation
.regulation of apoptotic process
  + 5 more...
.protein heterodimerization activity
.metal ion binding
.sequence-specific DNA binding
  + 2 more...
.plasma membrane
.cytoplasm
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland60
ascites150
bladder33
blood130
bone69
bone marrow20
brain51
cervix103
connective tissue20
embryonic tissue93
eye71
heart22
intestine43
kidney42
liver34
lung113
lymph158
lymph node11
mammary gland52
mouth30
muscle169
nerve64
ovary59
pancreas107
placenta52
prostate58
salivary gland49
skin251
spleen18
stomach20
testis18
thymus12
thyroid42
tonsil235
uterus43
vascular58
Health State
TissuesTPM*
normal39
bladder carcinoma56
breast (mammary gland) tumor75
cervical tumor28
chondrosarcoma24
colorectal tumor44
gastrointestinal tumor84
germ cell tumor60
glioma121
kidney tumor58
leukemia137
liver tumor52
lung tumor204
lymphoma138
non-neoplasia31
ovarian tumor39
pancreatic tumor180
primitive neuroectodermal tumor of the CNS118
prostate cancer77
retinoblastoma150
skin tumor414
soft tissue/muscle tissue tumor63
uterine tumor44
Developmental Stage
TissuesTPM*
adult65
embryoid body114
blastocyst81
fetus23
infant42
juvenile35
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue27.9
adrenal gland31.8
appendix29
bone marrow31.8
cerebral cortex36.5
colon23.6
duodenum30.1
esophagus28
gallbladder25.4
heart muscle48.2
kidney38.6
liver18.9
lung27.9
lymph node33.3
ovary22.3
pancreas11.8
placenta24.1
prostate28.6
salivary gland29.2
skin24.2
small intestine25.9
spleen30
stomach25.9
testis48.7
thyroid gland30.6
urinary bladder31.1
Tissues
TissuesExpression level
adrenal glandMedium
appendixHigh
bone marrowLow
breastMedium
bronchusHigh
cerebellumMedium
cerebral cortexMedium
cervix, uterineHigh
colonHigh
duodenumHigh
endometrium 1High
endometrium 2High
epididymisHigh
esophagusHigh
fallopian tubeHigh
gallbladderHigh
heart muscleMedium
hippocampusMedium
kidneyHigh
lateral ventricleMedium
liverLow
lungMedium
lymph nodeHigh
nasopharynxHigh
oral mucosaMedium
ovaryMedium
pancreasHigh
parathyroid glandHigh
placentaHigh
prostateHigh
rectumHigh
salivary glandHigh
seminal vesicleHigh
skeletal muscleLow
skin 1High
skin 2Medium
small intestineHigh
smooth muscleMedium
soft tissue 1Low
soft tissue 2Medium
spleenHigh
stomach 1High
stomach 2Medium
testisHigh
thyroid glandHigh
tonsilHigh
urinary bladderHigh
vaginaMedium
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*604853, gene) Mitochondrial ribosomal protein l28; MRPL28OMIM


#424, YPRC/BPRC, Industry-University Research Center, Yonsei Univ., Seodaemun-gu, Seoul, Korea, 120-749
Tel: +82-2-2123-6626, Fax: +82-2-393-6589
2014-2019 (C) Yonsei Proteome Research Center