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> Protein (NX_Q13137)
Protein (NX_Q13137)
Protein
Gene SymbolCALCOCO2 to neXtProt (NX_Q13137)
DescriptionCalcium-binding and coiled-coil domain-containing protein 2
Chromosome17
Location17q21.32 (46908350 ~ 46943884) to Ensembl
Sequene Features : Isoforms 5, Variants 36, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.response to interferon-gamma
.viral process
.protein homodimerization activity .perinuclear region of cytoplasm
.intracellular membrane-bounded organelle
.membrane
  + 4 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
5 36 6
2014-09-19protein level
5 28 6
2014-05-27protein level
5 28 6
2014-02-25protein level
5 28 6
2013-12-09protein level
5 26 6
2013-11-01protein level
5 26 6
2013-09-12protein level
5 26 6
2013-08-17protein level
5 26 6
2013-07-15protein level
2 17 2
2013-06-11protein level
2 17 2
2013-02-12protein level
2 10 0
2012-12-20protein level
2 9 0
2012-10-30protein level
1 10 0
2012-10-07protein level
1 10 0
2012-08-24protein level
1 10 0
2012-07-28protein level
1 10 0
2012-06-08protein level
1 12 0
2012-05-07protein level
1 9 0
2012-04-10protein level
1 9 0
2012-01-13protein level
1 11 0
2011-12-20protein level
1 11 0
2011-11-11protein level
1 11 0
2011-08-23protein level
1 11 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q13137-1
0 22 0 52220.4685
NX_Q13137-2
1 18 0 47310.1339
NX_Q13137-3
1 22 0 54569.6406
NX_Q13137-4
0 22 0 55152.9982
NX_Q13137-5
1 19 0 43641.258
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-739580,EBI-740058 LGALS8  
  .T cell costimulation
.plasma cell differentiation
.carbohydrate binding .extracellular exosome
.membrane
.cytoplasm
.extracellular space
2 EBI-739580,EBI-727004 SDCBP  
  .positive regulation of extracellular exosome assembly
.positive regulation of exosomal secretion
.ephrin receptor signaling pathway
  + 9 more...
.protein N-terminus binding
.protein heterodimerization activity
.syndecan binding
  + 4 more...
.blood microparticle
.extracellular exosome
.melanosome
  + 12 more...
3 EBI-739580,EBI-530034 PHF1  
  .positive regulation of histone H3-K27 methylation
.negative regulation of histone H3-K27 methylation
.negative regulation of gene expression, epigenetic
  + 5 more...
.methylated histone binding
.zinc ion binding
.sequence-specific DNA binding transcription factor activity
.site of double-strand break
.microtubule organizing center
.cytoplasm
  + 2 more...
4 EBI-739580,EBI-1048486 EEF1E1  
  .positive regulation of DNA damage response, signal transduction by p53 class mediator
.positive regulation of apoptotic process
.gene expression
  + 2 more...
.N/A .extracellular exosome
.cytosol
.cytoplasm
.nucleus
5 EBI-739580,EBI-8646694 DCX  
  .dendrite morphogenesis
.axon extension
.protein autophosphorylation
  + 8 more...
.protein kinase binding
.calcium-dependent protein serine/threonine kinase activity
.microtubule binding
  + 2 more...
.neuron projection
.microtubule associated complex
.microtubule
  + 4 more...
6 EBI-739580,EBI-749295 STK16  
  .cellular response to transforming growth factor beta stimulus
.protein autophosphorylation
.regulation of signal transduction
.ATP binding
.non-membrane spanning protein tyrosine kinase activity
.protein serine/threonine kinase activity
.RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
.perinuclear region of cytoplasm
.membrane
.Golgi-associated vesicle
.cytoplasm
7 EBI-739580,EBI-2513774 FARS2  
  .gene expression
.tRNA processing
.phenylalanyl-tRNA aminoacylation
.tRNA aminoacylation for protein translation
.ATP binding
.phenylalanine-tRNA ligase activity
.magnesium ion binding
.tRNA binding
.mitochondrial matrix
.mitochondrion
8 EBI-739580,EBI-1757866 MOS  
  .negative regulation of metaphase/anaphase transition of meiotic cell cycle
.establishment of meiotic spindle orientation
.protein autophosphorylation
  + 6 more...
.ATP binding
.MAP kinase kinase kinase activity
.protein serine/threonine kinase activity
.cytoplasm
9 EBI-739580,EBI-372475 SNRPB  
  .activation of mitophagy in response to mitochondrial depolarization
.ncRNA metabolic process
.mRNA 3'-end processing
  + 9 more...
.histone pre-mRNA DCP binding
.poly(A) RNA binding
.histone pre-mRNA 3'end processing complex
.catalytic step 2 spliceosome
.U2-type prespliceosome
  + 14 more...
10 EBI-739580,EBI-745290 HOXB9  
  .cell chemotaxis
.canonical Wnt signaling pathway
.embryonic skeletal system development
  + 4 more...
.sequence-specific DNA binding .mitochondrion
.nucleoplasm
11 EBI-739580,EBI-739696 LMO2  
  .cellular response to thyroid hormone stimulus
.positive regulation of transcription from RNA polymerase II promoter
.negative regulation of erythrocyte differentiation
  + 3 more...
.E-box binding
.cofactor binding
.bHLH transcription factor binding
  + 7 more...
.transcription factor complex
.nucleus
12 EBI-739580,EBI-351257 DDX6  
  .exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
.cytoplasmic mRNA processing body assembly
.viral RNA genome packaging
  + 4 more...
.poly(A) RNA binding
.protein domain specific binding
.ATP binding
  + 3 more...
.intracellular membrane-bounded organelle
.RISC complex
.membrane
  + 5 more...
13 EBI-739580,EBI-355765 VARS  
  .gene expression
.valyl-tRNA aminoacylation
.tRNA aminoacylation for protein translation
.ATP binding
.valine-tRNA ligase activity
.aminoacyl-tRNA editing activity
.cytosol
.mitochondrion
14 EBI-739580,EBI-750459 SRI  
  .negative regulation of transcription regulatory region DNA binding
.regulation of cell communication by electrical coupling involved in cardiac conduction
.regulation of high voltage-gated calcium channel activity
  + 20 more...
.protein heterodimerization activity
.ion channel binding
.calcium ion binding
  + 4 more...
.extracellular exosome
.dendritic spine neck
.axon terminus
  + 11 more...
15 EBI-739580,EBI-358122 RPL9  
  .cellular protein metabolic process
.viral transcription
.viral life cycle
  + 8 more...
.rRNA binding
.structural constituent of ribosome
.RNA binding
.cytosolic large ribosomal subunit
.membrane
.focal adhesion
  + 5 more...
16 EBI-739580,EBI-747693 NAA10  
  .N-terminal peptidyl-glutamic acid acetylation
.N-terminal peptidyl-serine acetylation
.internal protein amino acid acetylation
  + 2 more...
.peptide-glutamate-N-acetyltransferase activity
.peptide-serine-N-acetyltransferase activity
.N-acetyltransferase activity
.NatA complex
.cytosolic ribosome
.membrane
  + 4 more...
17 EBI-739580,EBI-750494 SMCP  
  .sperm motility
.penetration of zona pellucida
.N/A .mitochondrial membrane
.mitochondrion
.cytoplasm
18 EBI-739580,EBI-752241 MXI1  
  .cytoplasmic sequestering of transcription factor
.negative regulation of cell proliferation
.transcription, DNA-templated
.negative regulation of transcription from RNA polymerase II promoter
.transcription corepressor activity
.DNA binding
.cytoplasm
.nucleolus
.nucleus
19 EBI-739580,EBI-741406 CCNH  
  .positive regulation of viral transcription
.positive regulation of transcription from RNA polymerase II promoter
.negative regulation of gene expression, epigenetic
  + 20 more...
.cyclin-dependent protein serine/threonine kinase regulator activity
.kinase activity
.TFIIK complex
.cyclin-dependent protein kinase activating kinase holoenzyme complex
.holo TFIIH complex
  + 2 more...
20 EBI-739580,EBI-749995 TCL1A  
  .stem cell maintenance
.multicellular organismal development
.N/A .pronucleus
.cell cortex
.endoplasmic reticulum
21 EBI-739580,EBI-720116 GABARAPL2  
  .negative regulation of proteasomal protein catabolic process
.membrane fusion
.nucleophagy
  + 7 more...
.ATPase binding
.GABA receptor binding
.beta-tubulin binding
  + 2 more...
.cytoplasmic vesicle
.extrinsic component of membrane
.cytosol
  + 7 more...
22 EBI-739580,EBI-2798728 LMO4  
  .regulation of cell activation
.thymus development
.positive regulation of transcription from RNA polymerase II promoter
  + 8 more...
.zinc ion binding
.transcription factor binding
.sequence-specific DNA binding transcription factor activity
.enhancer sequence-specific DNA binding
.transcription factor complex
23 EBI-739580,EBI-357375 RPS27A  
  .programmed necrotic cell death
.apoptotic signaling pathway
.positive regulation of canonical Wnt signaling pathway
  + 90 more...
.metal ion binding
.poly(A) RNA binding
.structural constituent of ribosome
.extracellular exosome
.endocytic vesicle membrane
.cytosolic small ribosomal subunit
  + 8 more...
24 EBI-739580,EBI-10222656 AKAP17A  
  .regulation of RNA splicing
.B cell activation
.RNA splicing
  + 3 more...
.protein kinase A binding
.poly(A) RNA binding
.nucleotide binding
.nuclear speck
.cytoplasm
.spliceosomal complex
  + 2 more...
25 EBI-739580,EBI-717810 AES  
  .positive regulation of anoikis
.negative regulation of canonical Wnt signaling pathway
.response to interleukin-1
  + 12 more...
.transcription corepressor activity .nucleus
26 EBI-739580,EBI-602199 ARHGEF5  
  .positive regulation of podosome assembly
.regulation of GTPase activity
.intracellular signal transduction
  + 2 more...
.GTP binding
.Rho guanyl-nucleotide exchange factor activity
.N/A
27 EBI-739580,EBI-366017 RIN1  
  .negative regulation of synaptic plasticity
.associative learning
.memory
  + 2 more...
.GTPase activator activity .neuronal cell body
.dendrite
.plasma membrane
  + 2 more...
28 EBI-739580,EBI-1236916 PSME4  
  .positive regulation of canonical Wnt signaling pathway
.negative regulation of canonical Wnt signaling pathway
.regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
  + 24 more...
.lysine-acetylated histone binding
.peptidase activator activity
.spermatoproteasome complex
.nuclear speck
.cytosol
.nucleus
29 EBI-739580,EBI-10217913 RTP5  
  .N/A .N/A .integral component of membrane
30 EBI-739580,EBI-724310 DAZAP2  
  .N/A .WW domain binding .cytoplasm
.nucleus
31 EBI-739580,EBI-2341787 LONRF1  
  .N/A .zinc ion binding
.ATP-dependent peptidase activity
.N/A
32 EBI-739580,EBI-719941 FAM161A  
  .response to stimulus
.cilium assembly
.visual perception
.N/A .ciliary basal body
.photoreceptor connecting cilium
.centrosome
.cytoplasm
33 EBI-739580,EBI-2557469 PPP1R18  
  .N/A .N/A .cytoskeleton
.cytoplasm
34 EBI-739580,EBI-2802204 PAPD4  
  .histone mRNA catabolic process
.RNA polyadenylation
.mRNA processing
.hematopoietic progenitor cell differentiation
.metal ion binding
.ATP binding
.polynucleotide adenylyltransferase activity
.nuclear RNA-directed RNA polymerase complex
.cytoplasm
35 EBI-739580,EBI-995373 MAVS  
  .regulation of peroxisome organization
.positive regulation of IP-10 production
.positive regulation of chemokine (C-C motif) ligand 5 production
  + 22 more...
.CARD domain binding
.protein kinase binding
.signal transducer activity
.mitochondrial membrane
.integral component of membrane
.peroxisomal membrane
  + 2 more...
36 EBI-739580,EBI-10257651 LIMS2  
  .positive regulation of integrin-mediated signaling pathway
.negative regulation of hepatocyte proliferation
.negative regulation of neural precursor cell proliferation
  + 4 more...
.zinc ion binding .focal adhesion
.plasma membrane
.cytosol
.nucleus
37 EBI-739580,EBI-2858265 PEG10  
  .negative regulation of transforming growth factor beta receptor signaling pathway
.cell differentiation
.apoptotic process
.poly(A) RNA binding
.zinc ion binding
.DNA binding
.cytoplasm
.nucleus
38 EBI-739580,EBI-3916986 SPATA24  
  .cell differentiation
.spermatogenesis
.multicellular organismal development
  + 2 more...
.DNA binding .cytoplasm
.nucleolus
.nucleoplasm
.nucleus
39 EBI-739580,EBI-6658203 FAM90A1  
  .N/A .zinc ion binding
.nucleic acid binding
.N/A
40 EBI-739580,EBI-748515 GLYCTK  
  .protein phosphorylation .glycerate kinase activity
.ATP binding
.mitochondrion
.cytoplasm
41 EBI-739580,EBI-1104570 CEP57L1  
  .microtubule anchoring .N/A .microtubule
.microtubule organizing center
.cytoplasm
42 EBI-739580,EBI-745468 ARHGEF39  
  .positive regulation of cell migration .Rho guanyl-nucleotide exchange factor activity .plasma membrane
43 EBI-739580,EBI-724045 UBAC2  
  .protein localization to endoplasmic reticulum .N/A .integral component of membrane
.endoplasmic reticulum
44 EBI-739580,EBI-742750 BAHD1  
  .negative regulation of transcription, DNA-templated
.heterochromatin assembly
.transcription, DNA-templated
.chromatin silencing
.chromatin binding
.transcription regulatory region sequence-specific DNA binding
.chromatin silencing complex
.nucleoplasm
.chromatin
45 EBI-739580,EBI-10273713 ZNF564  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
46 EBI-739580,EBI-10244131 FBF1  
  .establishment of epithelial cell polarity
.apical junction assembly
.cilium assembly
.organelle organization
.N/A .ciliary transition fiber
.cell junction
.cytosol
  + 3 more...
47 EBI-739580,EBI-10276431 HDAC7  
  .positive regulation of cell migration involved in sprouting angiogenesis
.negative regulation of osteoblast differentiation
.cellular protein metabolic process
  + 8 more...
.NAD-dependent histone deacetylase activity (H3-K18 specific)
.14-3-3 protein binding
.repressing transcription factor binding
  + 9 more...
.cytoplasm
.nucleoplasm
.nucleus
.histone deacetylase complex
48 EBI-739580,EBI-923440 GATAD2B  
  .ATP-dependent chromatin remodeling
.transcription, DNA-templated
.sequence-specific DNA binding
.zinc ion binding
.sequence-specific DNA binding transcription factor activity
.protein complex
.nuclear speck
.nucleoplasm
.nuclear chromatin
49 EBI-739580,EBI-7957930 FAM168A  
  .N/A .N/A .N/A
50 EBI-739580,EBI-448771 DOCK2  
  .positive regulation of phagocytosis
.regulation of defense response to virus by virus
.alpha-beta T cell proliferation
  + 12 more...
.T cell receptor binding
.Rac guanyl-nucleotide exchange factor activity
.extracellular exosome
.membrane
.endomembrane system
  + 2 more...
51 EBI-739580,EBI-702328 TBRG4  
  .cellular respiration
.positive regulation of cell proliferation
.cell cycle arrest
.poly(A) RNA binding
.protein kinase activity
.mitochondrion
52 EBI-739580,EBI-746778 MAGOHB  
  .mRNA transport
.RNA splicing
.mRNA processing
.poly(A) RNA binding .catalytic step 2 spliceosome
.exon-exon junction complex
53 EBI-739580,EBI-726510 LENG1  
  .N/A .N/A .N/A
54 EBI-739580,EBI-742054 DDIT4L  
  .negative regulation of signal transduction .N/A .cytoplasm
55 EBI-739580,EBI-739588 TP53RK  
  .threonylcarbamoyladenosine metabolic process
.tRNA processing
.protein phosphorylation
.hydrolase activity
.ATP binding
.protein serine/threonine kinase activity
.p53 binding
.membrane
.cytosol
.nucleus
.EKC/KEOPS complex
56 EBI-739580,EBI-2514922 RBM15  
  .placenta blood vessel development
.ventricular septum morphogenesis
.spleen development
  + 4 more...
.poly(A) RNA binding
.nucleotide binding
.nuclear membrane
.nucleoplasm
57 EBI-739580,EBI-357275 PFDN5  
  .negative regulation of canonical Wnt signaling pathway
.retina development in camera-type eye
.'de novo' posttranslational protein folding
  + 4 more...
.transcription corepressor activity .prefoldin complex
.cytoplasm
.nucleus
58 EBI-739580,EBI-725647 LITAF  
  .cellular response to lipopolysaccharide
.positive regulation of I-kappaB kinase/NF-kappaB signaling
.negative regulation of NF-kappaB import into nucleus
  + 6 more...
.WW domain binding
.signal transducer activity
.intracellular membrane-bounded organelle
.plasma membrane
.Golgi apparatus
  + 3 more...
59 EBI-739580,EBI-10298556 LMF2  
  .N/A .N/A .integral component of membrane
.membrane
.endoplasmic reticulum membrane
60 EBI-739580,EBI-2924519 DUSP26  
  .positive regulation of peptidyl-serine dephosphorylation
.negative regulation of ERK1 and ERK2 cascade
.positive regulation of cell adhesion
  + 4 more...
.protein tyrosine/serine/threonine phosphatase activity
.protein tyrosine phosphatase activity
.phosphoprotein phosphatase activity
  + 3 more...
.extracellular exosome
.Golgi apparatus
.mitochondrion
  + 2 more...
61 EBI-739580,EBI-744935 C20orf195  
  .N/A .N/A .extracellular exosome
62 EBI-739580,EBI-8644516 TEKT3  
  .regulation of fertilization
.cilium morphogenesis
.sperm motility
.N/A .extracellular exosome
.sperm flagellum
.microtubule
  + 2 more...
63 EBI-739580,EBI-745073 BEX2  
  .regulation of cell cycle
.regulation of apoptotic process
.cell cycle
.apoptotic process
.N/A .cytoplasm
.nucleus
64 EBI-739580,EBI-746969 GABARAPL1  
  .membrane fusion
.nucleophagy
.mitochondrion degradation
.autophagic vacuole assembly
.GABA receptor binding
.beta-tubulin binding
.Tat protein binding
.microtubule binding
.cell body
.dendrite cytoplasm
.dendrite membrane
  + 10 more...
65 EBI-739580,EBI-749353 METTL17  
  .translation .methyltransferase activity
.copper ion binding
.ribosome
.mitochondrion
.nucleoplasm
.nucleus
66 EBI-739580,EBI-712912 CBX8  
  .cellular protein metabolic process
.post-translational protein modification
.protein sumoylation
  + 3 more...
.methylated histone binding
.ubiquitin-protein transferase activity
.single-stranded RNA binding
.PRC1 complex
.PcG protein complex
.nucleoplasm
  + 3 more...
67 EBI-739580,EBI-371876 EXOSC5  
  .RNA phosphodiester bond hydrolysis, exonucleolytic
.polyadenylation-dependent snoRNA 3'-end processing
.nuclear mRNA surveillance
  + 10 more...
.RNA binding
.3'-5'-exoribonuclease activity
.transcriptionally active chromatin
.cytosol
.cytoplasm
  + 5 more...
68 EBI-739580,EBI-8787464 TBC1D22B  
  .N/A .GTPase activator activity .N/A
69 EBI-739580,EBI-2556166 MTPAP  
  .histone mRNA catabolic process
.mRNA polyadenylation
.transcription, DNA-templated
.poly(A) RNA binding
.protein homodimerization activity
.identical protein binding
  + 5 more...
.intracellular membrane-bounded organelle
.mitochondrion
70 EBI-739580,EBI-743375 CHCHD3  
  .mitochondrial fusion
.inner mitochondrial membrane organization
.negative regulation of transcription from RNA polymerase II promoter
.protein complex scaffold
.phosphatase binding
.RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
.extracellular exosome
.mitochondrial inner membrane
.mitochondrion
  + 2 more...
71 EBI-739580,EBI-745520 ZNF581  
  .transcription from RNA polymerase II promoter
.regulation of transcription from RNA polymerase II promoter
.metal ion binding
.RNA polymerase II regulatory region sequence-specific DNA binding
.nucleus
72 EBI-739580,EBI-739890 KLHL42  
  .cell division
.proteasome-mediated ubiquitin-dependent protein catabolic process
.regulation of microtubule-based process
  + 2 more...
.N/A .Cul3-RING ubiquitin ligase complex
.spindle
.cytoplasm
73 EBI-739580,EBI-724639 PEF1  
  .response to calcium ion
.proteolysis
.protein dimerization activity
.protein heterodimerization activity
.poly(A) RNA binding
  + 2 more...
.extracellular exosome
.membrane
.cytoplasm
74 EBI-739580,EBI-356402 TBK1  
  .defense response to virus
.defense response to Gram-positive bacterium
.positive regulation of transcription from RNA polymerase II promoter
  + 20 more...
.phosphoprotein binding
.ATP binding
.protein serine/threonine kinase activity
  + 2 more...
.endosome membrane
.cytosol
.cytoplasm
75 EBI-739580,EBI-719882 FKBPL  
  .chaperone-mediated protein folding
.response to radiation
.protein peptidyl-prolyl isomerization
.FK506 binding
.peptidyl-prolyl cis-trans isomerase activity
.endoplasmic reticulum membrane
76 EBI-739580,EBI-10172526 MID2  
  .negative regulation of viral release from host cell
.positive regulation of NF-kappaB transcription factor activity
.positive regulation of sequence-specific DNA binding transcription factor activity
  + 6 more...
.phosphoprotein binding
.protein heterodimerization activity
.protein homodimerization activity
  + 3 more...
.extracellular exosome
.microtubule
.cytoplasm
77 EBI-739580,EBI-2134033 DCTN4  
  .antigen processing and presentation of exogenous peptide antigen via MHC class II
.nuclear migration
.protein N-terminus binding .dynactin complex
.cytoplasmic dynein complex
.cytosol
  + 3 more...
78 EBI-739580,EBI-725252 NFU1  
  .iron-sulfur cluster assembly .4 iron, 4 sulfur cluster binding
.iron ion binding
.cytosol
.mitochondrion
.cytoplasm
  + 2 more...
79 EBI-739580,EBI-715161 DUSP12  
  .peptidyl-tyrosine dephosphorylation
.positive regulation of glucokinase activity
.protein dephosphorylation
.cellular protein modification process
.zinc ion binding
.protein tyrosine/serine/threonine phosphatase activity
.protein tyrosine phosphatase activity
.cytoplasm
.nucleus
80 EBI-739580,EBI-714987 ZNF337  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
81 EBI-739580,EBI-8583355 AMMECR1  
  .N/A .N/A .N/A
82 EBI-739580,EBI-372521 LSM4  
  .activation of mitophagy in response to mitochondrial depolarization
.exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
.gene expression
  + 4 more...
.poly(A) RNA binding .small nuclear ribonucleoprotein complex
.cytosol
.U6 snRNP
.spliceosomal complex
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue155
adrenal gland273
ascites100
bladder167
blood229
bone181
bone marrow41
brain111
cervix82
connective tissue114
ear62
embryonic tissue37
esophagus198
eye52
heart301
intestine94
kidney175
liver112
lung89
lymph67
lymph node55
mammary gland99
mouth211
muscle244
nerve64
ovary59
pancreas103
parathyroid582
pharynx220
pituitary gland60
placenta95
prostate100
salivary gland296
skin52
spleen468
stomach177
testis163
thymus288
thyroid236
tonsil235
trachea231
umbilical cord72
uterus129
vascular212
Health State
TissuesTPM*
normal133
adrenal tumor79
breast (mammary gland) tumor75
cervical tumor28
chondrosarcoma132
colorectal tumor62
esophageal tumor173
gastrointestinal tumor135
germ cell tumor83
glioma27
head and neck tumor149
kidney tumor174
leukemia74
liver tumor124
lung tumor68
lymphoma110
non-neoplasia217
ovarian tumor78
pancreatic tumor133
primitive neuroectodermal tumor of the CNS102
prostate cancer48
retinoblastoma43
skin tumor23
soft tissue/muscle tissue tumor207
uterine tumor77
Developmental Stage
TissuesTPM*
adult97
embryoid body71
blastocyst32
neonate193
fetus59
infant127
juvenile179
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue115
adrenal gland73.3
appendix74.1
bone marrow48
cerebral cortex43.9
colon106.2
duodenum75.4
esophagus92.8
gallbladder78.3
heart muscle106.1
kidney68
liver76.2
lung89.6
lymph node64.7
ovary104.3
pancreas32.2
placenta68.1
prostate58.4
salivary gland51.9
skin60.3
small intestine88.1
spleen81
stomach73.4
testis139.8
thyroid gland90.8
urinary bladder75.2
Tissues
TissuesExpression level
adrenal glandLow
appendixMedium
bone marrowMedium
breastLow
bronchusLow
cerebellumLow
cerebral cortexMedium
cervix, uterineLow
colonMedium
duodenumMedium
endometrium 1Low
endometrium 2Medium
epididymisMedium
esophagusLow
fallopian tubeMedium
gallbladderMedium
heart muscleLow
hippocampusLow
kidneyMedium
lateral ventricleLow
liverLow
lungMedium
lymph nodeLow
nasopharynxLow
oral mucosaLow
ovaryLow
pancreasMedium
parathyroid glandLow
placentaMedium
prostateLow
rectumMedium
salivary glandLow
seminal vesicleLow
skeletal muscleLow
skin 1Low
skin 2Medium
small intestineMedium
smooth muscleLow
soft tissue 1Low
soft tissue 2Low
stomach 1Medium
stomach 2Medium
testisMedium
thyroid glandMedium
tonsilMedium
urinary bladderMedium
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*604587, gene) Calcium binding and coiled-coil domain protein 2; CALCOCO2OMIM


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