No. |
Exp. ref. |
Symbol |
|
PE |
Pr |
Ab |
Di |
|
GO: Biological Process |
GO: Mulecular Function |
GO: Cellular Component |
|
1 |
EBI-1045887,EBI-741237 |
SORBS3 |
|
| | | | |
.positive regulation of stress fiber assembly .positive regulation of cytoskeleton organization .positive regulation of MAPK cascade + 5 more... |
.vinculin binding .structural constituent of cytoskeleton |
.focal adhesion .cytoskeleton .cytosol .nucleus |
|
2 |
EBI-1045887,EBI-311323 |
SORBS2 |
|
| | | | |
.cell migration .cell adhesion .actin filament organization |
.metal ion binding .poly(A) RNA binding .structural constituent of muscle + 2 more... |
.perinuclear region of cytoplasm .Z disc .actin cytoskeleton + 2 more... |
|
3 |
EBI-1045887,EBI-365996 |
RAF1 |
|
| | | | |
.regulation of cell motility .negative regulation of extrinsic apoptotic signaling pathway via death domain receptors .death-inducing signaling complex assembly + 36 more... |
.metal ion binding .identical protein binding .ATP binding + 3 more... |
.pseudopodium .plasma membrane .cytosol + 4 more... |
|
4 |
EBI-1045887,EBI-346340 |
HCK |
|
| | | | |
.positive regulation of actin cytoskeleton reorganization .regulation of podosome assembly .cellular response to peptide hormone stimulus + 28 more... |
.ATP binding .receptor binding .non-membrane spanning protein tyrosine kinase activity .protein tyrosine kinase activity |
.cell projection .extrinsic component of cytoplasmic side of plasma membrane .transport vesicle + 7 more... |
|
5 |
EBI-1045887,EBI-621482 |
SRC |
|
| | | | |
.regulation of caveolin-mediated endocytosis .negative regulation of intrinsic apoptotic signaling pathway .negative regulation of extrinsic apoptotic signaling pathway + 100 more... |
.scaffold protein binding .growth factor receptor binding .hormone receptor binding + 14 more... |
.extracellular exosome .perinuclear region of cytoplasm .neuron projection + 13 more... |
|
6 |
EBI-1045887,EBI-389883 |
NCK1 |
|
| | | | |
.negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress .negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation .negative regulation of PERK-mediated unfolded protein response + 23 more... |
.eukaryotic initiation factor eIF2 binding .receptor tyrosine kinase binding .protein binding, bridging + 5 more... |
.vesicle membrane .cell-cell junction .plasma membrane + 6 more... |
|
7 |
EBI-1045887,EBI-466029 |
HTT |
|
| | | | |
.negative regulation of extrinsic apoptotic signaling pathway .iron ion homeostasis .L-glutamate import + 38 more... |
.diazepam binding .beta-tubulin binding .dynein intermediate chain binding + 6 more... |
.protein complex .cytoplasmic vesicle membrane .dendrite + 11 more... |
|
8 |
EBI-1045887,EBI-444403 |
LIMK1 |
|
| | | | |
.positive regulation of stress fiber assembly .negative regulation of ubiquitin-protein transferase activity .ephrin receptor signaling pathway + 11 more... |
.heat shock protein binding .zinc ion binding .ATP binding + 2 more... |
.neuron projection .focal adhesion .cytosol + 2 more... |
|
9 |
EBI-1045887,EBI-523958 |
CASP7 |
|
| | | | |
.execution phase of apoptosis .intrinsic apoptotic signaling pathway .programmed cell death + 4 more... |
.cysteine-type endopeptidase activity involved in execution phase of apoptosis .cysteine-type peptidase activity .cysteine-type endopeptidase activity |
.cytosol .cytoplasm .nucleoplasm .nucleus |
|
10 |
EBI-1045887,EBI-81752 |
CDC42 |
|
| | | | |
.positive regulation of substrate adhesion-dependent cell spreading .positive regulation of intracellular protein transport .epithelial cell-cell adhesion + 61 more... |
.identical protein binding .apolipoprotein A-I receptor binding .thioesterase binding + 3 more... |
.mitotic spindle .extracellular exosome .spindle midzone + 17 more... |
|
11 |
EBI-1045887,EBI-401755 |
GRB2 |
|
| | | | |
.positive regulation of reactive oxygen species metabolic process .cellular response to ionizing radiation .branching involved in labyrinthine layer morphogenesis + 25 more... |
.ephrin receptor binding .poly(A) RNA binding .insulin receptor substrate binding + 6 more... |
.Grb2-EGFR complex .extracellular exosome .vesicle membrane + 10 more... |
|
12 |
EBI-1045887,EBI-413628 |
RAC1 |
|
| | | | |
.positive regulation of substrate adhesion-dependent cell spreading .apoptotic signaling pathway .ruffle assembly + 63 more... |
.Rho GDP-dissociation inhibitor binding .thioesterase binding .enzyme binding + 2 more... |
.extracellular exosome .melanosome .cytoplasmic ribonucleoprotein granule + 12 more... |
|
13 |
EBI-1045887,EBI-717515 |
ARHGEF7 |
|
| | | | |
.positive regulation of lamellipodium morphogenesis .positive regulation of substrate adhesion-dependent cell spreading .apoptotic signaling pathway + 14 more... |
.protein kinase binding .Rho guanyl-nucleotide exchange factor activity .guanyl-nucleotide exchange factor activity |
.protein complex .neuronal cell body .neuron projection + 5 more... |
|
14 |
EBI-1045887,EBI-1642523 |
ARHGEF6 |
|
| | | | |
.apoptotic signaling pathway .regulation of small GTPase mediated signal transduction .neurotrophin TRK receptor signaling pathway + 7 more... |
.GTPase activator activity .Rho guanyl-nucleotide exchange factor activity |
.lamellipodium .cell-cell junction .cytosol .intracellular |
|
15 |
EBI-1045887,EBI-7975674 |
SH3RF3 |
|
| | | | |
.N/A |
.zinc ion binding |
.N/A |
|
16 |
EBI-1045887,EBI-433642 |
SORBS1 |
|
| | | | |
.positive regulation of establishment of protein localization to plasma membrane .focal adhesion assembly .positive regulation of lipid biosynthetic process + 9 more... |
.cytoskeletal protein binding .insulin receptor binding .SH3/SH2 adaptor activity .actin binding |
.membrane raft .nuclear matrix .focal adhesion + 10 more... |
|
17 |
EBI-1045887,EBI-6285694 |
RHOJ |
|
| | | | |
.retina vasculature morphogenesis in camera-type eye .regulation of small GTPase mediated signal transduction .actin cytoskeleton organization + 4 more... |
.GTP binding .GTPase activity |
.extracellular exosome .plasma membrane .cytosol |
|