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> Protein (NX_Q13190)
Protein (NX_Q13190)
Protein
Gene SymbolSTX5 to neXtProt (NX_Q13190)
DescriptionSyntaxin-5
Chromosome11
Location11q12.3 (62574369 ~ 62599560) to Ensembl
Sequene Features : Isoforms 4, Variants 45, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.regulation of Golgi organization
.Golgi disassembly
.vesicle fusion with Golgi apparatus
  + 7 more...
.protein N-terminus binding
.SNAP receptor activity
.SNARE binding
.endoplasmic reticulum-Golgi intermediate compartment membrane
.vesicle
.SNARE complex
  + 5 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
4 45 5
2014-09-19protein level
4 40 5
2014-05-27protein level
4 40 5
2014-02-25protein level
3 40 5
2013-12-09protein level
3 27 5
2013-11-01protein level
3 27 5
2013-09-12protein level
3 27 5
2013-08-17protein level
3 27 5
2013-07-15protein level
3 19 2
2013-06-11protein level
3 19 2
2013-02-12protein level
3 13 0
2012-12-20protein level
3 14 0
2012-10-30protein level
3 14 0
2012-10-07protein level
3 14 0
2012-08-24protein level
3 10 0
2012-07-28protein level
3 9 0
2012-06-08protein level
3 9 0
2012-05-07protein level
3 9 0
2012-04-10protein level
3 9 0
2012-01-13protein level
3 6 0
2011-12-20protein level
3 6 0
2011-11-11protein level
3 6 0
2011-08-23protein level
3 6 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q13190-1
0 19 0 39647.7132
NX_Q13190-2
0 17 0 34064.7846
NX_Q13190-3
0 14 0 29868.4734
NX_Q13190-4
0 16 0 35451.402
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-714206,EBI-624237 TACC1  
  .cell division
.regulation of microtubule-based process
.interkinetic nuclear migration
  + 5 more...
.N/A .intermediate filament cytoskeleton
.microtubule cytoskeleton
.microtubule organizing center
  + 2 more...
2 EBI-714206,EBI-1045155 MAGEA6  
  .N/A .N/A .N/A
3 EBI-714206,EBI-744942 STX4  
  .positive regulation of protein localization to cell surface
.positive regulation of protein localization to plasma membrane
.regulation of extrinsic apoptotic signaling pathway via death domain receptors
  + 21 more...
.sphingomyelin phosphodiesterase activator activity
.SNAP receptor activity
.SNARE binding
.extracellular exosome
.perinuclear region of cytoplasm
.synapse
  + 19 more...
4 EBI-714206,EBI-749265 CCDC155  
  .chromosome localization to nuclear envelope involved in homologous chromosome segregation
.oogenesis
.spermatogenesis
  + 2 more...
.N/A .integral component of membrane
.nuclear outer membrane
.lateral element
.chromosome, telomeric region
5 EBI-714206,EBI-3921185 NAPB  
  .membrane fusion
.SNARE complex disassembly
.intracellular protein transport
.syntaxin binding
.soluble NSF attachment protein activity
.extracellular exosome
.SNARE complex
.vacuolar membrane
6 EBI-714206,EBI-368382 COG4  
  .Golgi vesicle prefusion complex stabilization
.protein transport
.Golgi organization
.retrograde vesicle-mediated transport, Golgi to ER
.N/A .Golgi transport complex
.Golgi membrane
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland60
ascites75
bladder33
blood89
bone27
bone marrow102
brain34
cervix41
connective tissue20
embryonic tissue37
eye110
heart33
intestine56
kidney23
larynx127
liver63
lung71
lymph67
lymph node55
mammary gland59
mouth15
muscle28
nerve64
ovary49
pancreas28
pituitary gland60
placenta84
prostate168
salivary gland49
skin52
spleen131
stomach125
testis45
thymus50
thyroid64
uterus30
vascular19
Health State
TissuesTPM*
normal51
adrenal tumor158
breast (mammary gland) tumor64
chondrosarcoma36
colorectal tumor53
gastrointestinal tumor126
germ cell tumor11
glioma65
head and neck tumor59
kidney tumor29
leukemia116
liver tumor124
lung tumor48
lymphoma55
non-neoplasia31
ovarian tumor39
pancreatic tumor38
primitive neuroectodermal tumor of the CNS86
prostate cancer154
retinoblastoma21
skin tumor47
soft tissue/muscle tissue tumor63
uterine tumor22
Developmental Stage
TissuesTPM*
adult62
embryoid body42
blastocyst48
neonate64
fetus43
juvenile53
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue18.7
adrenal gland24.8
appendix22.5
bone marrow26.6
cerebral cortex17.3
colon21.8
duodenum20.2
esophagus23.8
gallbladder28.4
heart muscle16.3
kidney21
liver19.7
lung25.3
lymph node26.1
ovary34.3
pancreas16
placenta28.8
prostate24.4
salivary gland39
skin23
small intestine22.4
spleen23.6
stomach24.5
testis25.3
thyroid gland42
urinary bladder28.4
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*603189, gene) Syntaxin 5; STX5OMIM


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