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> Protein (NX_Q13336)
Protein (NX_Q13336)
Protein
Gene SymbolSLC14A1 to neXtProt (NX_Q13336)
DescriptionUrea transporter 1
Chromosome18
Location18q12.3 (43304092 ~ 43332485) to Ensembl
Sequene Features : Isoforms 2, Variants 89, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.urea transmembrane transport
.transmembrane transport
.urea transport
.urea channel activity
.urea transmembrane transporter activity
.water transmembrane transporter activity
.basolateral plasma membrane
.integral component of plasma membrane
.plasma membrane
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 89 1
2014-09-19protein level
2 58 1
2014-05-27protein level
2 58 1
2014-02-25protein level
2 58 1
2013-12-09protein level
2 48 1
2013-11-01protein level
2 47 1
2013-09-12protein level
2 47 1
2013-08-17protein level
2 47 1
2013-07-15protein level
2 37 1
2013-06-11protein level
2 37 1
2013-02-12transcript level
2 21 2
2012-12-20transcript level
2 21 2
2012-10-30transcript level
2 26 2
2012-10-07transcript level
2 26 1
2012-08-24transcript level
2 23 1
2012-07-28transcript level
2 23 1
2012-06-08transcript level
2 26 1
2012-05-07transcript level
2 23 1
2012-04-10transcript level
2 23 1
2012-01-13transcript level
2 20 1
2011-12-20transcript level
2 20 1
2011-11-11transcript level
2 20 1
2011-08-23transcript level
2 19 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q13336-1
1 11 0 42499.6384
NX_Q13336-2
2 11 0 48309.531
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
bladder100
blood73
bone69
brain64
connective tissue26
heart78
intestine8
kidney18
lung8
mammary gland6
muscle28
nerve128
ovary19
pancreas4
prostate131
skin9
stomach10
thymus37
uterus17
vascular77
Health State
TissuesTPM*
normal29
breast (mammary gland) tumor10
chondrosarcoma60
glioma65
kidney tumor14
non-neoplasia206
ovarian tumor26
prostate cancer9
soft tissue/muscle tissue tumor7
uterine tumor44
Developmental Stage
TissuesTPM*
adult32
neonate64
fetus12
infant42
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue3.2
adrenal gland1.6
appendix1.8
bone marrow11
cerebral cortex11
colon1.8
duodenum2.6
esophagus1.2
gallbladder12.8
heart muscle17.2
kidney17.7
lung9.7
lymph node2.1
pancreas1.3
placenta2.1
prostate55.1
salivary gland2.2
small intestine2.5
spleen2.5
stomach2.4
thyroid gland11.8
urinary bladder44.6
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(#111000, phenotype) Blood group--kidd system; JKOMIM
2(*613868, gene) Solute carrier family 14 (urea transporter), member 1; SLC14A1OMIM


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