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	> Protein (NX_Q13433) Protein (NX_Q13433) Protein Gene Symbol SLC39A6 to neXtProt (NX_Q13433) Description Zinc transporter ZIP6 Chromosome 18 Location 18q12.2 (33688495 ~ 33709348) to Ensembl Sequene Features : Isoforms 2, Variants 87, PTMs 15 to neXtProt Sequence Features Gene Ontologies GO: Biological Process GO: Mulecular Function GO: Cellular Component .zinc II ion transmembrane import .zinc II ion transmembrane transport .transmembrane transport .cellular zinc ion homeostasis .zinc ion transmembrane transporter activity .lamellipodium membrane .cell surface .integral component of plasma membrane   + 2 more... Proteomic Evidences Release Protein Evidence Pr Ab Isoforms Variants PTMs 2015-01-01 protein level 2 87 15 2014-09-19 protein level 2 67 15 2014-05-27 protein level 2 67 15 2014-02-25 protein level 2 67 15 2013-12-09 protein level 2 54 15 2013-11-01 protein level 2 52 15 2013-09-12 protein level 2 52 15 2013-08-17 protein level 2 52 15 2013-07-15 protein level 2 32 6 2013-06-11 protein level 2 32 6 2013-02-12 protein level 2 6 9 2012-12-20 protein level 2 9 9 2012-10-30 protein level 2 10 9 2012-10-07 protein level 2 10 7 2012-08-24 protein level 2 7 7 2012-07-28 protein level 2 7 7 2012-06-08 protein level 2 8 7 2012-05-07 protein level 2 8 7 2012-04-10 protein level 2 8 7 2012-01-13 protein level 2 3 7 2011-12-20 protein level 2 3 7 2011-11-11 protein level 2 3 7 2011-08-23 protein level 2 3 7 Protein Isoforms Isoform Ac   U G S Mw (Da) NX_Q13433-1 17 10 0 84993.0189 NX_Q13433-2 2 10 0 48574.1188 : Uniquely mapped peptide : Gene-specific peptide : Shared peptide EST expression level of Protein Coding Gene (ref. NCBI UniGene EST) Body Sites Tissues TPM* adrenal gland 30 bladder 100 blood 24 bone 13 bone marrow 20 brain 35 cervix 20 connective tissue 46 ear 559 embryonic tissue 56 eye 52 heart 11 intestine 51 kidney 52 larynx 255 liver 43 lung 47 lymph 45 mammary gland 238 mouth 75 muscle 28 nerve 193 ovary 39 pancreas 32 pharynx 49 pituitary gland 60 placenta 42 prostate 247 skin 56 spleen 18 stomach 31 testis 39 thymus 62 thyroid 386 trachea 96 uterus 94 vascular 58 Health State Tissues TPM* normal 49 adrenal tumor 79 breast (mammary gland) tumor 247 cervical tumor 28 chondrosarcoma 36 colorectal tumor 79 gastrointestinal tumor 33 germ cell tumor 18 glioma 18 head and neck tumor 224 kidney tumor 58 leukemia 21 liver tumor 62 lung tumor 19 lymphoma 27 non-neoplasia 31 ovarian tumor 52 pancreatic tumor 47 primitive neuroectodermal tumor of the CNS 39 prostate cancer 288 retinoblastoma 64 skin tumor 31 soft tissue/muscle tissue tumor 39 uterine tumor 199 Developmental Stage Tissues TPM* adult 93 embryoid body 28 blastocyst 32 fetus 59 juvenile 71 TPM*: Transcripts per million; transcript expression level measured by expression sequence tags. Expression level of Protein (ref. Human Protein Atlas) RNA-Seq. Tissues FPKM adipose tissue 24 adrenal gland 27.6 appendix 21.9 bone marrow 7 cerebral cortex 31.8 colon 13.5 duodenum 9.3 esophagus 16.6 gallbladder 26.6 heart muscle 11.9 kidney 24.2 liver 9.4 lung 17 lymph node 17.1 ovary 42.8 pancreas 17.8 placenta 33.5 prostate 123.4 salivary gland 22.9 skin 44.6 small intestine 7.9 spleen 13.4 stomach 15.9 testis 21.8 thyroid gland 38.1 urinary bladder 50 Tissues Tissues Expression level adrenal gland High bone marrow Low breast Low bronchus Low cerebellum Medium cerebral cortex Low cervix, uterine Low colon Medium duodenum Medium endometrium 1 Medium endometrium 2 High epididymis Medium esophagus Medium fallopian tube Medium gallbladder Medium heart muscle Medium hippocampus Low kidney Medium liver Medium nasopharynx Medium oral mucosa Low pancreas Medium parathyroid gland Low prostate Medium rectum Low salivary gland Low skin 1 Low skin 2 Low small intestine Medium smooth muscle Medium soft tissue 1 Low soft tissue 2 Low stomach 1 Medium stomach 2 Low testis Medium tonsil Low urinary bladder Low Cancer Tumor Number of patients and Staining levels breast cancer carcinoid cervical cancer colorectal cancer endometrial cancer glioma head and neck cancer liver cancer lung cancer lymphoma melanoma ovarian cancer pancreatic cancer prostate cancer renal cancer skin cancer stomach cancer testis cancer thyroid cancer urothelial cancer RNA-seq colour codes Highly expressed RNAs (FPKM >50) Moderately expressed RNAs (50> FPKM >10) Lower expressed RNAs (10> FPKM >1) The lowest expressed RNAs (FPKM value of 0 or 1) Expression level colour codes Highly expressed protein Moderately expressed protein Lower expressed protein Staining level colour codes Highly expressed protein Moderately expressed protein Lower expressed protein Not Detected Disease No. Disease Description Ref. 1 (*608731, gene) Solute carrier family 39 (zinc transporter), member 6; SLC39A6 OMIM

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