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Protein |
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Gene Symbol | SLC39A6 to neXtProt (NX_Q13433) |
Description | Zinc transporter ZIP6 |
Chromosome | 18 |
Location | 18q12.2 (33688495 ~ 33709348) to Ensembl |
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Sequene Features : Isoforms 2, Variants 87, PTMs 15 to neXtProt Sequence Features
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Gene Ontologies |
GO: Biological Process |
GO: Mulecular Function |
GO: Cellular Component |
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.zinc II ion transmembrane import .zinc II ion transmembrane transport .transmembrane transport .cellular zinc ion homeostasis |
.zinc ion transmembrane transporter activity |
.lamellipodium membrane .cell surface .integral component of plasma membrane + 2 more... |
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Proteomic Evidences |
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Release | | Protein Evidence | | Pr | | Ab | | Isoforms | | Variants | | PTMs |
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2015-01-01 | | protein level | | | | | | | 2 |
| 87 |
| 15 |
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2014-09-19 | | protein level | | | | | | | 2 |
| 67 |
| 15 |
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2014-05-27 | | protein level | | | | | | | 2 |
| 67 |
| 15 |
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2014-02-25 | | protein level | | | | | | | 2 |
| 67 |
| 15 |
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2013-12-09 | | protein level | | | | | | | 2 |
| 54 |
| 15 |
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2013-11-01 | | protein level | | | | | | | 2 |
| 52 |
| 15 |
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2013-09-12 | | protein level | | | | | | | 2 |
| 52 |
| 15 |
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2013-08-17 | | protein level | | | | | | | 2 |
| 52 |
| 15 |
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2013-07-15 | | protein level | | | | | | | 2 |
| 32 |
| 6 |
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2013-06-11 | | protein level | | | | | | | 2 |
| 32 |
| 6 |
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2013-02-12 | | protein level | | | | | | | 2 |
| 6 |
| 9 |
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2012-12-20 | | protein level | | | | | | | 2 |
| 9 |
| 9 |
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2012-10-30 | | protein level | | | | | | | 2 |
| 10 |
| 9 |
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2012-10-07 | | protein level | | | | | | | 2 |
| 10 |
| 7 |
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2012-08-24 | | protein level | | | | | | | 2 |
| 7 |
| 7 |
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2012-07-28 | | protein level | | | | | | | 2 |
| 7 |
| 7 |
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2012-06-08 | | protein level | | | | | | | 2 |
| 8 |
| 7 |
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2012-05-07 | | protein level | | | | | | | 2 |
| 8 |
| 7 |
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2012-04-10 | | protein level | | | | | | | 2 |
| 8 |
| 7 |
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2012-01-13 | | protein level | | | | | | | 2 |
| 3 |
| 7 |
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2011-12-20 | | protein level | | | | | | | 2 |
| 3 |
| 7 |
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2011-11-11 | | protein level | | | | | | | 2 |
| 3 |
| 7 |
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2011-08-23 | | protein level | | | | | | | 2 |
| 3 |
| 7 |
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Protein Isoforms |
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| : Uniquely mapped peptide | | : Gene-specific peptide | | : Shared peptide |
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EST expression level of Protein Coding Gene (ref. NCBI UniGene EST) |
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Body Sites | |
Tissues | TPM* | |
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adrenal gland | 30 | |
bladder | 100 | |
blood | 24 | |
bone | 13 | |
bone marrow | 20 | |
brain | 35 | |
cervix | 20 | |
connective tissue | 46 | |
ear | 559 | |
embryonic tissue | 56 | |
eye | 52 | |
heart | 11 | |
intestine | 51 | |
kidney | 52 | |
larynx | 255 | |
liver | 43 | |
lung | 47 | |
lymph | 45 | |
mammary gland | 238 | |
mouth | 75 | |
muscle | 28 | |
nerve | 193 | |
ovary | 39 | |
pancreas | 32 | |
pharynx | 49 | |
pituitary gland | 60 | |
placenta | 42 | |
prostate | 247 | |
skin | 56 | |
spleen | 18 | |
stomach | 31 | |
testis | 39 | |
thymus | 62 | |
thyroid | 386 | |
trachea | 96 | |
uterus | 94 | |
vascular | 58 | |
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Health State | |
Tissues | TPM* | |
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normal | 49 | |
adrenal tumor | 79 | |
breast (mammary gland) tumor | 247 | |
cervical tumor | 28 | |
chondrosarcoma | 36 | |
colorectal tumor | 79 | |
gastrointestinal tumor | 33 | |
germ cell tumor | 18 | |
glioma | 18 | |
head and neck tumor | 224 | |
kidney tumor | 58 | |
leukemia | 21 | |
liver tumor | 62 | |
lung tumor | 19 | |
lymphoma | 27 | |
non-neoplasia | 31 | |
ovarian tumor | 52 | |
pancreatic tumor | 47 | |
primitive neuroectodermal tumor of the CNS | 39 | |
prostate cancer | 288 | |
retinoblastoma | 64 | |
skin tumor | 31 | |
soft tissue/muscle tissue tumor | 39 | |
uterine tumor | 199 | |
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Developmental Stage | |
Tissues | TPM* | |
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adult | 93 | |
embryoid body | 28 | |
blastocyst | 32 | |
fetus | 59 | |
juvenile | 71 | |
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TPM*: Transcripts per million; transcript expression level measured by expression sequence tags. |
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Expression level of Protein (ref. Human Protein Atlas) |
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RNA-Seq. | |
Tissues | FPKM | |
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adipose tissue | 24 | |
adrenal gland | 27.6 | |
appendix | 21.9 | |
bone marrow | 7 | |
cerebral cortex | 31.8 | |
colon | 13.5 | |
duodenum | 9.3 | |
esophagus | 16.6 | |
gallbladder | 26.6 | |
heart muscle | 11.9 | |
kidney | 24.2 | |
liver | 9.4 | |
lung | 17 | |
lymph node | 17.1 | |
ovary | 42.8 | |
pancreas | 17.8 | |
placenta | 33.5 | |
prostate | 123.4 | |
salivary gland | 22.9 | |
skin | 44.6 | |
small intestine | 7.9 | |
spleen | 13.4 | |
stomach | 15.9 | |
testis | 21.8 | |
thyroid gland | 38.1 | |
urinary bladder | 50 | |
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Tissues | |
Tissues | Expression level |
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adrenal gland | High | |
bone marrow | Low | |
breast | Low | |
bronchus | Low | |
cerebellum | Medium | |
cerebral cortex | Low | |
cervix, uterine | Low | |
colon | Medium | |
duodenum | Medium | |
endometrium 1 | Medium | |
endometrium 2 | High | |
epididymis | Medium | |
esophagus | Medium | |
fallopian tube | Medium | |
gallbladder | Medium | |
heart muscle | Medium | |
hippocampus | Low | |
kidney | Medium | |
liver | Medium | |
nasopharynx | Medium | |
oral mucosa | Low | |
pancreas | Medium | |
parathyroid gland | Low | |
prostate | Medium | |
rectum | Low | |
salivary gland | Low | |
skin 1 | Low | |
skin 2 | Low | |
small intestine | Medium | |
smooth muscle | Medium | |
soft tissue 1 | Low | |
soft tissue 2 | Low | |
stomach 1 | Medium | |
stomach 2 | Low | |
testis | Medium | |
tonsil | Low | |
urinary bladder | Low | |
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Cancer | |
Tumor | Number of patients and Staining levels | |
breast cancer | |
carcinoid | |
cervical cancer | |
colorectal cancer | |
endometrial cancer | |
glioma | |
head and neck cancer | |
liver cancer | |
lung cancer | |
lymphoma | |
melanoma | |
ovarian cancer | |
pancreatic cancer | |
prostate cancer | |
renal cancer | |
skin cancer | |
stomach cancer | |
testis cancer | |
thyroid cancer | |
urothelial cancer | |
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RNA-seq colour codes |
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Highly expressed RNAs (FPKM >50) |
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Moderately expressed RNAs (50> FPKM >10) |
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Lower expressed RNAs (10> FPKM >1) |
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The lowest expressed RNAs (FPKM value of 0 or 1) |
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Expression level colour codes |
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Highly expressed protein |
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Moderately expressed protein |
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Lower expressed protein |
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Staining level colour codes |
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Highly expressed protein |
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Moderately expressed protein |
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Lower expressed protein |
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Not Detected |
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Disease |
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No. | Disease Description | Ref. |
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1 | (*608731, gene) Solute carrier family 39 (zinc transporter), member 6; SLC39A6 | OMIM |
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