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> Protein (NX_Q13465)
Protein (NX_Q13465)
Protein
Gene SymbolMECOM to neXtProt (NX_Q13465)
DescriptionMDS1 and EVI1 complex locus protein MDS1
Chromosome3
Location3q26.2 (168801287 ~ 169381406) to Ensembl
Sequene Features : Isoforms 1, Variants 2, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.regulation of transcription, DNA-templated .sequence-specific DNA binding transcription factor activity .N/A
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01transcript level
1 2 0
2014-09-19transcript level
1 2 0
2014-05-27transcript level
1 2 0
2014-02-25transcript level
1 2 0
2013-12-09transcript level
1 2 0
2013-11-01transcript level
1 2 0
2013-09-12transcript level
1 2 0
2013-08-17transcript level
1 2 0
2013-07-15transcript level
1 2 0
2013-06-11transcript level
1 2 0
2013-02-12transcript level
1 2 0
2012-12-20transcript level
1 2 0
2012-10-30transcript level
1 1 0
2012-10-07transcript level
1 1 0
2012-08-24transcript level
1 1 0
2012-07-28transcript level
1 1 0
2012-06-08transcript level
1 1 0
2012-05-07transcript level
1 2 0
2012-04-10transcript level
1 2 0
2012-01-13transcript level
1 2 0
2011-12-20transcript level
1 2 0
2011-11-11transcript level
1 2 0
2011-08-23transcript level
1 2 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q13465-1
3 0 4 18684.2175
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-8475192,EBI-10692254 RABGAP1L  
  .positive regulation of GTPase activity
.regulation of protein localization
.Rab GTPase binding
.GTPase activator activity
.Golgi apparatus
.early endosome
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
ascites125
bladder100
bone marrow20
brain10
connective tissue20
embryonic tissue9
eye23
intestine25
kidney28
larynx42
liver9
lung20
mammary gland19
mouth105
muscle159
ovary49
pancreas18
pharynx24
placenta35
prostate15
skin9
stomach62
testis13
trachea308
umbilical cord145
uterus64
vascular58
Health State
TissuesTPM*
normal23
breast (mammary gland) tumor21
chondrosarcoma12
colorectal tumor44
gastrointestinal tumor59
germ cell tumor11
head and neck tumor59
kidney tumor14
leukemia10
liver tumor10
non-neoplasia31
ovarian tumor65
pancreatic tumor19
skin tumor7
soft tissue/muscle tissue tumor15
uterine tumor88
Developmental Stage
TissuesTPM*
adult32
embryoid body28
neonate64
fetus12
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue12.3
adrenal gland1.2
appendix7.7
cerebral cortex2.2
colon25.1
duodenum19.1
esophagus17.7
gallbladder9.7
heart muscle11.1
kidney38.3
liver1.1
lung28.9
lymph node2.1
ovary1.5
pancreas10
placenta11.8
prostate6.4
salivary gland6.3
skin2.2
small intestine9.9
spleen6.6
stomach58.7
testis2.9
thyroid gland5.5
urinary bladder38
Tissues
TissuesExpression level
adrenal glandHigh
appendixHigh
bone marrowLow
breastHigh
bronchusHigh
cerebellumHigh
cerebral cortexHigh
cervix, uterineHigh
colonHigh
duodenumHigh
endometrium 1High
endometrium 2High
epididymisHigh
esophagusHigh
fallopian tubeHigh
gallbladderHigh
heart muscleHigh
hippocampusHigh
kidneyHigh
lateral ventricleHigh
liverMedium
lungHigh
lymph nodeHigh
nasopharynxHigh
oral mucosaHigh
ovaryHigh
pancreasHigh
parathyroid glandMedium
placentaHigh
prostateHigh
rectumHigh
salivary glandHigh
seminal vesicleHigh
skeletal muscleHigh
skin 1High
skin 2High
small intestineHigh
smooth muscleHigh
soft tissue 1High
soft tissue 2High
spleenHigh
stomach 1High
stomach 2High
testisHigh
thyroid glandHigh
tonsilHigh
urinary bladderHigh
vaginaHigh
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*600049, gene) Mds1 gene; MDS1OMIM


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