Home| Contact Us

HOME SEARCH STATISTICS
> Protein (NX_Q13796)
Protein (NX_Q13796)
Protein
Gene SymbolSHROOM2 to neXtProt (NX_Q13796)
DescriptionProtein Shroom2
ChromosomeX
LocationXp22.2 (9754496 ~ 9917483) to Ensembl
Sequene Features : Isoforms 1, Variants 220, PTMs 14 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.camera-type eye morphogenesis
.cell-cell junction maintenance
.apical protein localization
  + 11 more...
.actin filament binding
.ligand-gated sodium channel activity
.beta-catenin binding
.actin binding
.extracellular exosome
.neuronal cell body
.filamentous actin
  + 7 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 220 14
2014-09-19protein level
1 171 14
2014-05-27protein level
1 171 14
2014-02-25protein level
1 170 14
2013-12-09protein level
1 127 14
2013-11-01protein level
1 123 14
2013-09-12protein level
1 123 14
2013-08-17protein level
1 123 14
2013-07-15protein level
1 87 14
2013-06-11protein level
1 87 14
2013-02-12protein level
1 53 12
2012-12-20protein level
1 51 12
2012-10-30protein level
1 61 12
2012-10-07protein level
1 61 12
2012-08-24protein level
1 60 12
2012-07-28protein level
1 60 12
2012-06-08protein level
1 50 12
2012-05-07protein level
1 50 12
2012-04-10protein level
1 50 12
2012-01-13protein level
1 22 12
2011-12-20protein level
1 22 12
2011-11-11protein level
1 22 11
2011-08-23protein level
1 22 11
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q13796-1
81 0 3 176302.0002
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-1644065,EBI-389883 NCK1  
  .negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
.negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation
.negative regulation of PERK-mediated unfolded protein response
  + 23 more...
.eukaryotic initiation factor eIF2 binding
.receptor tyrosine kinase binding
.protein binding, bridging
  + 5 more...
.vesicle membrane
.cell-cell junction
.plasma membrane
  + 6 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
bladder33
bone13
brain48
connective tissue6
embryonic tissue28
eye33
intestine4
kidney4
liver4
lung5
mammary gland6
mouth15
muscle9
ovary19
pharynx73
placenta14
prostate47
skin28
testis25
trachea19
uterus8
Health State
TissuesTPM*
normal24
bladder carcinoma56
gastrointestinal tumor8
germ cell tumor11
glioma37
head and neck tumor22
liver tumor10
lung tumor9
ovarian tumor26
primitive neuroectodermal tumor of the CNS15
prostate cancer48
skin tumor47
soft tissue/muscle tissue tumor7
uterine tumor22
Developmental Stage
TissuesTPM*
adult15
embryoid body42
blastocyst48
fetus41
juvenile35
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adrenal gland1.4
cerebral cortex6.7
colon1.6
esophagus2.6
gallbladder3.4
kidney2.8
liver1.8
lung2.9
ovary6.4
pancreas1.9
placenta5.3
prostate4.9
salivary gland2.4
skin2.9
stomach1.2
testis3.5
thyroid gland1.4
urinary bladder3.7
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*300103, gene) Shroom family member 2; SHROOM2OMIM


#424, YPRC/BPRC, Industry-University Research Center, Yonsei Univ., Seodaemun-gu, Seoul, Korea, 120-749
Tel: +82-2-2123-6626, Fax: +82-2-393-6589
2014-2019 (C) Yonsei Proteome Research Center