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> Protein (NX_Q13887)
Protein (NX_Q13887)
Protein
Gene SymbolKLF5 to neXtProt (NX_Q13887)
DescriptionKrueppel-like factor 5
Chromosome13
Location13q22.1 (73629114 ~ 73651676) to Ensembl
Sequene Features : Isoforms 3, Variants 62, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.cellular response to peptide
.cellular response to organic cyclic compound
.intestinal epithelial cell development
  + 9 more...
.metal ion binding
.RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
.RNA polymerase II core promoter proximal region sequence-specific DNA binding
.intracellular membrane-bounded organelle
.plasma membrane
.Golgi apparatus
  + 2 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
3 62 0
2014-09-19protein level
3 50 0
2014-05-27protein level
3 50 0
2014-02-25protein level
3 50 0
2013-12-09protein level
3 47 0
2013-11-01protein level
3 45 0
2013-09-12protein level
3 45 0
2013-08-17protein level
3 45 0
2013-07-15protein level
1 26 0
2013-06-11protein level
1 26 0
2013-02-12protein level
1 13 0
2012-12-20protein level
1 13 0
2012-10-30protein level
1 12 0
2012-10-07protein level
1 12 0
2012-08-24protein level
1 11 0
2012-07-28protein level
1 11 0
2012-06-08protein level
1 12 0
2012-05-07protein level
1 6 0
2012-04-10protein level
1 6 0
2012-01-13protein level
1 6 0
2011-12-20protein level
1 6 0
2011-11-11protein level
1 6 0
2011-08-23protein level
1 6 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q13887-1
5 10 2 50759.2381
NX_Q13887-2
1 9 2 33596.6002
NX_Q13887-3
3 4 0 18104.4704
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-2696013,EBI-3390054 UBC  
  .programmed necrotic cell death
.apoptotic signaling pathway
.energy homeostasis
  + 90 more...
.poly(A) RNA binding
.protease binding
.extracellular exosome
.endocytic vesicle membrane
.endosome membrane
  + 3 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
ascites150
bladder200
bone13
bone marrow20
brain11
cervix41
connective tissue26
embryonic tissue14
eye23
intestine224
kidney14
larynx340
liver34
lung68
mammary gland13
mouth181
muscle28
ovary59
pancreas84
pharynx147
placenta70
prostate47
skin33
stomach261
testis62
thyroid42
trachea77
uterus38
Health State
TissuesTPM*
normal29
bladder carcinoma284
cervical tumor28
chondrosarcoma24
colorectal tumor319
gastrointestinal tumor244
germ cell tumor22
glioma18
head and neck tumor209
kidney tumor14
liver tumor52
lung tumor29
non-neoplasia51
ovarian tumor65
pancreatic tumor85
prostate cancer28
retinoblastoma21
skin tumor7
soft tissue/muscle tissue tumor23
uterine tumor99
Developmental Stage
TissuesTPM*
adult72
embryoid body14
blastocyst16
fetus16
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue2.7
adrenal gland5.7
appendix16.6
bone marrow45.1
cerebral cortex1.4
colon135.8
duodenum98.3
esophagus292.5
gallbladder57.8
heart muscle2.1
kidney7.1
liver2.9
lung32.3
lymph node1.9
ovary5.8
pancreas5.3
placenta22.9
prostate17
salivary gland30.6
skin151.5
small intestine111.7
spleen1.2
stomach72.6
testis29.3
thyroid gland24.8
urinary bladder75.8
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*602903, gene) Kruppel-like factor 5; KLF5OMIM


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