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> Protein (NX_Q14008)
Protein (NX_Q14008)
Protein
Gene SymbolCKAP5 to neXtProt (NX_Q14008)
DescriptionCytoskeleton-associated protein 5
Chromosome11
Location11p11.2 (46764598 ~ 46867847) to Ensembl
Sequene Features : Isoforms 3, Variants 170, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.cell division
.centrosome organization
.RNA transport
  + 7 more...
.N/A .protein complex
.membrane
.cytosol
  + 2 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
3 170 8
2014-09-19protein level
3 123 8
2014-05-27protein level
3 123 8
2014-02-25protein level
3 121 8
2013-12-09protein level
3 96 8
2013-11-01protein level
3 88 3
2013-09-12protein level
3 88 3
2013-08-17protein level
3 88 3
2013-07-15protein level
3 45 3
2013-06-11protein level
3 45 3
2013-02-12protein level
3 20 6
2012-12-20protein level
3 19 6
2012-10-30protein level
3 24 6
2012-10-07protein level
3 24 2
2012-08-24protein level
3 19 2
2012-07-28protein level
3 19 2
2012-06-08protein level
3 22 2
2012-05-07protein level
3 21 2
2012-04-10protein level
3 21 2
2012-01-13protein level
3 15 2
2011-12-20protein level
3 15 2
2011-11-11protein level
3 15 2
2011-08-23protein level
3 15 2
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q14008-1
0 106 0 225351.1239
NX_Q14008-2
1 102 0 218386.6448
NX_Q14008-3
1 105 0 226113.4083
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-310585,EBI-624237 TACC1  
  .cell division
.regulation of microtubule-based process
.interkinetic nuclear migration
  + 5 more...
.N/A .intermediate filament cytoskeleton
.microtubule cytoskeleton
.microtubule organizing center
  + 2 more...
2 EBI-310585,EBI-389883 NCK1  
  .negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
.negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation
.negative regulation of PERK-mediated unfolded protein response
  + 23 more...
.eukaryotic initiation factor eIF2 binding
.receptor tyrosine kinase binding
.protein binding, bridging
  + 5 more...
.vesicle membrane
.cell-cell junction
.plasma membrane
  + 6 more...
3 EBI-310585,EBI-2554984 TACC3  
  .regulation of cell cycle
.cytoplasmic sequestering of transcription factor
.regulation of microtubule-based process
  + 8 more...
.N/A .centrosome
.cytoplasm
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland91
ascites25
bladder133
blood32
bone125
bone marrow61
brain103
cervix82
connective tissue80
ear559
embryonic tissue220
esophagus49
eye90
heart189
intestine142
kidney113
liver92
lung77
lymph45
lymph node100
mammary gland178
mouth15
muscle84
nerve64
ovary49
pancreas28
parathyroid145
pharynx122
pituitary gland60
placenta21
prostate105
salivary gland49
skin71
spleen56
stomach62
testis213
thymus25
thyroid171
tonsil58
trachea77
uterus112
vascular77
Health State
TissuesTPM*
normal92
adrenal tumor158
bladder carcinoma56
breast (mammary gland) tumor139
cervical tumor115
chondrosarcoma156
colorectal tumor168
esophageal tumor57
gastrointestinal tumor84
germ cell tumor167
glioma65
head and neck tumor44
kidney tumor58
leukemia63
liver tumor114
lung tumor77
lymphoma96
non-neoplasia20
ovarian tumor78
pancreatic tumor38
primitive neuroectodermal tumor of the CNS47
prostate cancer96
retinoblastoma150
skin tumor111
soft tissue/muscle tissue tumor167
uterine tumor144
Developmental Stage
TissuesTPM*
adult107
embryoid body171
blastocyst374
neonate32
fetus145
juvenile89
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue14.5
adrenal gland42.3
appendix20.3
bone marrow17.7
cerebral cortex44
colon21.2
duodenum17.8
esophagus16.1
gallbladder17.6
heart muscle22.7
kidney13.5
liver18.2
lung12.7
lymph node26
ovary38.7
pancreas6.7
placenta20.5
prostate18.9
salivary gland10
skin20.3
small intestine14.4
spleen15.1
stomach19.1
testis57.2
thyroid gland13.7
urinary bladder20.9
Tissues
TissuesExpression level
adrenal glandHigh
appendixMedium
bone marrowMedium
breastMedium
bronchusHigh
cerebellumMedium
cerebral cortexMedium
cervix, uterineHigh
colonHigh
duodenumHigh
endometrium 1Medium
endometrium 2High
epididymisMedium
esophagusMedium
fallopian tubeMedium
gallbladderHigh
heart muscleMedium
hippocampusMedium
kidneyHigh
lateral ventricleMedium
liverMedium
lungHigh
lymph nodeMedium
nasopharynxHigh
oral mucosaMedium
ovaryMedium
pancreasMedium
parathyroid glandMedium
placentaHigh
prostateMedium
rectumHigh
salivary glandMedium
seminal vesicleMedium
skeletal muscleMedium
skin 1Medium
skin 2High
small intestineHigh
smooth muscleMedium
soft tissue 1High
soft tissue 2High
spleenMedium
stomach 1High
stomach 2High
testisHigh
thyroid glandHigh
tonsilMedium
urinary bladderMedium
vaginaHigh
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*611142, gene) Cytoskeleton-associated protein 5; CKAP5OMIM


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