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> Protein (NX_Q14061)
Protein (NX_Q14061)
Protein
Gene SymbolCOX17 to neXtProt (NX_Q14061)
DescriptionCytochrome c oxidase copper chaperone
Chromosome3
Location3q13.33 (119373360 ~ 119396301) to Ensembl
Sequene Features : Isoforms 1, Variants 4, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.heart development
.brain development
.copper ion transport
.generation of precursor metabolites and energy
.copper chaperone activity
.copper ion binding
.mitochondrial intermembrane space
.mitochondrion
.cytoplasm
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 4 3
2014-09-19protein level
1 4 3
2014-05-27protein level
1 4 3
2014-02-25protein level
1 4 3
2013-12-09protein level
1 2 3
2013-11-01protein level
1 2 3
2013-09-12protein level
1 2 3
2013-08-17protein level
1 2 3
2013-07-15protein level
1 1 3
2013-06-11protein level
1 1 3
2013-02-12protein level
1 0 2
2012-12-20protein level
1 0 2
2012-10-30protein level
1 0 2
2012-10-07protein level
1 0 2
2012-08-24protein level
1 0 2
2012-07-28protein level
1 0 2
2012-06-08protein level
1 0 2
2012-05-07protein level
1 3 2
2012-04-10protein level
1 3 2
2012-01-13protein level
1 2 2
2011-12-20protein level
1 2 2
2011-11-11protein level
1 2 2
2011-08-23protein level
1 2 2
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q14061-1
3 0 0 6910.3609
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-711311,EBI-743591 KATNAL1  
  .microtubule severing
.cytoplasmic microtubule organization
.metabolic process
.spermatogenesis
.microtubule-severing ATPase activity
.ATP binding
.microtubule
.cytoplasm
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
ascites25
bladder33
blood40
bone27
bone marrow82
brain21
connective tissue20
ear62
embryonic tissue14
eye62
heart234
intestine60
kidney37
liver97
lung53
lymph node11
mammary gland46
mouth15
muscle84
ovary9
pancreas46
parathyroid97
pharynx73
pituitary gland302
placenta17
prostate52
skin9
stomach10
testis27
thyroid42
trachea19
uterus56
vascular19
Health State
TissuesTPM*
normal53
adrenal tumor79
breast (mammary gland) tumor10
chondrosarcoma12
colorectal tumor26
gastrointestinal tumor8
germ cell tumor18
glioma111
head and neck tumor29
kidney tumor14
leukemia31
liver tumor41
pancreatic tumor95
primitive neuroectodermal tumor of the CNS7
prostate cancer48
skin tumor7
soft tissue/muscle tissue tumor15
uterine tumor33
Developmental Stage
TissuesTPM*
adult38
embryoid body14
fetus61
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue18.6
adrenal gland46.2
appendix22.8
bone marrow15.4
cerebral cortex16.1
colon17.5
duodenum19.7
esophagus10.3
gallbladder7.9
heart muscle37.6
kidney25.7
liver18.1
lung15.9
lymph node20.2
ovary7.1
pancreas12.1
placenta15
prostate22.9
salivary gland14.7
skin4.8
small intestine21.4
spleen17.7
stomach23.6
testis16.2
thyroid gland14.9
urinary bladder9.8
Tissues
TissuesExpression level
adrenal glandHigh
appendixHigh
bone marrowLow
breastMedium
bronchusHigh
cerebellumHigh
cerebral cortexMedium
cervix, uterineMedium
colonHigh
duodenumHigh
endometrium 1Medium
endometrium 2Medium
epididymisMedium
esophagusMedium
fallopian tubeHigh
gallbladderHigh
heart muscleHigh
hippocampusMedium
kidneyHigh
lateral ventricleMedium
liverHigh
lungMedium
lymph nodeHigh
nasopharynxHigh
oral mucosaMedium
ovaryLow
pancreasHigh
parathyroid glandHigh
placentaHigh
prostateMedium
rectumHigh
salivary glandHigh
seminal vesicleHigh
skeletal muscleHigh
skin 1High
skin 2Medium
small intestineHigh
smooth muscleLow
soft tissue 1Low
soft tissue 2Low
spleenHigh
stomach 1High
stomach 2High
testisHigh
thyroid glandHigh
tonsilHigh
urinary bladderMedium
vaginaLow
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*604813, gene) Cytochrome c oxidase assembly protein cox17; COX17OMIM


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