Home| Contact Us

HOME SEARCH STATISTICS
> Protein (NX_Q14151)
Protein (NX_Q14151)
Protein
Gene SymbolSAFB2 to neXtProt (NX_Q14151)
DescriptionScaffold attachment factor B2
Chromosome19
Location19p13.3 (5587010 ~ 5624057) to Ensembl
Sequene Features : Isoforms 2, Variants 101, PTMs 17 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.regulation of transcription, DNA-templated
.transcription, DNA-templated
.poly(A) RNA binding
.identical protein binding
.DNA binding
.nucleotide binding
.extracellular exosome
.intracellular membrane-bounded organelle
.cytoplasm
.nucleoplasm
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 101 17
2014-09-19protein level
1 81 17
2014-05-27protein level
1 81 33
2014-02-25protein level
1 82 31
2013-12-09protein level
1 59 31
2013-11-01protein level
1 55 26
2013-09-12protein level
1 55 28
2013-08-17protein level
1 55 28
2013-07-15protein level
1 35 27
2013-06-11protein level
1 35 27
2013-02-12protein level
1 14 29
2012-12-20protein level
1 16 29
2012-10-30protein level
1 18 29
2012-10-07protein level
1 18 29
2012-08-24protein level
1 12 29
2012-07-28protein level
1 12 29
2012-06-08protein level
1 13 27
2012-05-07protein level
1 12 27
2012-04-10protein level
1 12 27
2012-01-13protein level
1 9 27
2011-12-20protein level
1 9 27
2011-11-11protein level
1 9 20
2011-08-23protein level
1 9 20
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q14151-1
21 3 9 107407.7664
NX_Q14151-2
1 3 0 12161.1434
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-352869,EBI-1222956 SORBS3  
  .positive regulation of stress fiber assembly
.positive regulation of cytoskeleton organization
.positive regulation of MAPK cascade
  + 5 more...
.vinculin binding
.structural constituent of cytoskeleton
.focal adhesion
.cytoskeleton
.cytosol
.nucleus
2 EBI-352869,EBI-78473 ESR1  
  .cellular response to estradiol stimulus
.epithelial cell proliferation involved in mammary gland duct elongation
.mammary gland alveolus development
  + 33 more...
.ATPase binding
.identical protein binding
.estrogen-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
  + 14 more...
.transcriptionally active chromatin
.integral component of membrane
.membrane
  + 5 more...
3 EBI-352869,EBI-348298 SAFB  
  .positive regulation of transcription from RNA polymerase II promoter
.hormone metabolic process
.growth
  + 3 more...
.poly(A) RNA binding
.double-stranded DNA binding
.chromatin binding
  + 2 more...
.nucleoplasm
.nucleus
4 EBI-352869,EBI-373144 MAP1LC3B  
  .regulation of mitochondrion degradation
.membrane fusion
.nucleophagy
  + 3 more...
.microtubule binding .cytoplasmic vesicle
.organelle membrane
.extrinsic component of membrane
  + 9 more...
5 EBI-352869,EBI-746969 GABARAPL1  
  .membrane fusion
.nucleophagy
.mitochondrion degradation
.autophagic vacuole assembly
.GABA receptor binding
.beta-tubulin binding
.Tat protein binding
.microtubule binding
.cell body
.dendrite cytoplasm
.dendrite membrane
  + 10 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland91
bladder66
blood16
bone27
bone marrow20
brain62
cervix41
connective tissue6
embryonic tissue42
esophagus99
eye119
intestine51
kidney104
larynx42
liver29
lung38
lymph90
lymph node22
mammary gland59
mouth30
muscle28
nerve128
ovary49
pancreas70
pituitary gland60
placenta17
prostate47
salivary gland148
skin61
spleen93
stomach62
testis20
thymus100
thyroid85
trachea38
uterus56
vascular19
Health State
TissuesTPM*
normal42
adrenal tumor79
breast (mammary gland) tumor64
cervical tumor57
chondrosarcoma12
colorectal tumor44
esophageal tumor115
gastrointestinal tumor42
germ cell tumor45
glioma83
head and neck tumor59
kidney tumor145
leukemia42
liver tumor31
lung tumor38
lymphoma69
non-neoplasia51
ovarian tumor65
pancreatic tumor57
primitive neuroectodermal tumor of the CNS55
prostate cancer48
retinoblastoma215
skin tumor87
soft tissue/muscle tissue tumor47
uterine tumor55
Developmental Stage
TissuesTPM*
adult37
embryoid body42
blastocyst16
fetus32
juvenile35
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue28.1
adrenal gland38.2
appendix37.8
bone marrow41.6
cerebral cortex30.3
colon25.7
duodenum31.8
esophagus19.2
gallbladder28.1
heart muscle20
kidney37.1
liver16.3
lung27.8
lymph node40.4
ovary55.1
pancreas17.9
placenta23.3
prostate40.8
salivary gland23.9
skin28.9
small intestine32.3
spleen48.5
stomach28.2
testis41.9
thyroid gland34
urinary bladder21.9
Tissues
TissuesExpression level
adrenal glandHigh
appendixHigh
bone marrowMedium
breastHigh
bronchusHigh
cerebellumHigh
cerebral cortexHigh
cervix, uterineHigh
colonHigh
duodenumHigh
endometrium 1High
endometrium 2High
epididymisHigh
esophagusMedium
fallopian tubeHigh
gallbladderHigh
heart muscleHigh
hippocampusMedium
kidneyHigh
lateral ventricleHigh
liverMedium
lungHigh
lymph nodeMedium
nasopharynxHigh
oral mucosaHigh
ovaryMedium
pancreasHigh
placentaHigh
prostateHigh
rectumHigh
salivary glandHigh
seminal vesicleHigh
skeletal muscleMedium
skin 1Medium
skin 2High
small intestineHigh
smooth muscleMedium
soft tissue 1Medium
spleenMedium
stomach 1High
stomach 2High
testisHigh
thyroid glandHigh
tonsilHigh
urinary bladderHigh
vaginaHigh
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*608066, gene) Scaffold attachment factor b2; SAFB2OMIM


#424, YPRC/BPRC, Industry-University Research Center, Yonsei Univ., Seodaemun-gu, Seoul, Korea, 120-749
Tel: +82-2-2123-6626, Fax: +82-2-393-6589
2014-2019 (C) Yonsei Proteome Research Center