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> Protein (NX_Q14533)
Protein (NX_Q14533)
Protein
Gene SymbolKRT81 to neXtProt (NX_Q14533)
DescriptionKeratin, type II cuticular Hb1
Chromosome12
Location12q13.13 (52679697 ~ 52685318) to Ensembl
Sequene Features : Isoforms 1, Variants 59, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .structural molecule activity .keratin filament
.extracellular space
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 59 0
2014-09-19protein level
1 44 0
2014-05-27protein level
1 44 2
2014-02-25protein level
1 43 2
2013-12-09protein level
1 32 2
2013-11-01protein level
1 30 2
2013-09-12protein level
1 30 2
2013-08-17protein level
1 30 2
2013-07-15protein level
1 24 2
2013-06-11protein level
1 24 2
2013-02-12protein level
1 19 2
2012-12-20protein level
1 18 2
2012-10-30protein level
1 22 2
2012-10-07protein level
1 22 2
2012-08-24protein level
1 21 2
2012-07-28protein level
1 21 2
2012-06-08protein level
1 22 2
2012-05-07protein level
1 22 2
2012-04-10protein level
1 22 2
2012-01-13protein level
1 16 2
2011-12-20protein level
1 16 2
2011-11-11protein level
1 16 0
2011-08-23protein level
1 16 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q14533-1
4 0 22 54892.6127
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-739648,EBI-1047263 KRT38  
  .N/A .structural molecule activity .extracellular exosome
.intermediate filament
2 EBI-739648,EBI-740446 OTX1  
  .diencephalon morphogenesis
.positive regulation of transcription from RNA polymerase II promoter
.inner ear morphogenesis
  + 3 more...
.RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
.RNA polymerase II core promoter proximal region sequence-specific DNA binding
.nucleus
3 EBI-739648,EBI-948001 KRT31  
  .epidermis development .structural constituent of cytoskeleton .extracellular exosome
.intermediate filament
.extracellular space
4 EBI-739648,EBI-10171697 KRT40  
  .N/A .structural molecule activity .intermediate filament
5 EBI-739648,EBI-739657 KXD1  
  .vesicle-mediated transport .N/A .BLOC-1 complex
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
blood16
bone572
connective tissue228
embryonic tissue4
eye4
heart11
intestine4
lung104
mammary gland284
pancreas103
pharynx49
placenta10
prostate10
skin4
Health State
TissuesTPM*
normal3
breast (mammary gland) tumor461
chondrosarcoma458
colorectal tumor8
head and neck tumor14
leukemia10
lung tumor340
pancreatic tumor209
prostate cancer9
soft tissue/muscle tissue tumor271
Developmental Stage
TissuesTPM*
adult62
embryoid body14
fetus1
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
placenta1.5
salivary gland1
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Disease
No.Disease DescriptionRef.
1(#158000, phenotype) MonilethrixOMIM
2(*602153, gene) Keratin 81; KRT81OMIM


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