Home| Contact Us

HOME SEARCH STATISTICS
> Protein (NX_Q14565)
Protein (NX_Q14565)
Protein
Gene SymbolDMC1 to neXtProt (NX_Q14565)
DescriptionMeiotic recombination protein DMC1/LIM15 homolog
Chromosome22
Location22q13.1 (38914954 ~ 38966291) to Ensembl
Sequene Features : Isoforms 2, Variants 37, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.female gamete generation
.spermatid development
.spermatogenesis
  + 7 more...
.DNA-dependent ATPase activity
.ATP binding
.DNA binding
.chromosome
.nucleus
.condensed nuclear chromosome
.chromosome, telomeric region
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 37 0
2014-09-19protein level
2 27 0
2014-05-27protein level
1 27 0
2014-02-25protein level
1 26 0
2013-12-09protein level
1 24 0
2013-11-01protein level
1 20 0
2013-09-12protein level
1 20 0
2013-08-17protein level
1 20 0
2013-07-15protein level
1 11 0
2013-06-11protein level
1 11 0
2013-02-12protein level
1 6 0
2012-12-20protein level
1 6 0
2012-10-30protein level
1 6 0
2012-10-07protein level
1 6 0
2012-08-24protein level
1 4 0
2012-07-28protein level
1 4 0
2012-06-08protein level
1 7 0
2012-05-07protein level
1 7 0
2012-04-10protein level
1 7 0
2012-01-13protein level
1 7 0
2011-12-20protein level
1 7 0
2011-11-11protein level
1 7 0
2011-08-23protein level
1 7 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q14565-1
4 11 0 37657.2042
NX_Q14565-2
1 11 0 31539.1127
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-930865,EBI-727004 SDCBP  
  .positive regulation of extracellular exosome assembly
.positive regulation of exosomal secretion
.ephrin receptor signaling pathway
  + 9 more...
.protein N-terminus binding
.protein heterodimerization activity
.syndecan binding
  + 4 more...
.blood microparticle
.extracellular exosome
.melanosome
  + 12 more...
2 EBI-930865,EBI-348380 PSMA3  
  .positive regulation of canonical Wnt signaling pathway
.negative regulation of canonical Wnt signaling pathway
.regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
  + 23 more...
.threonine-type endopeptidase activity
.endopeptidase activity
.extracellular exosome
.proteasome core complex, alpha-subunit complex
.proteasome core complex
  + 5 more...
3 EBI-930865,EBI-740098 TRIM23  
  .positive regulation of catalytic activity
.protein ubiquitination
.viral process
.small GTPase mediated signal transduction
.identical protein binding
.GDP binding
.ligase activity
  + 5 more...
.extracellular exosome
.lysosomal membrane
.nucleus
.Golgi membrane
4 EBI-930865,EBI-79792 BRCA2  
  .centrosome duplication
.replication fork protection
.positive regulation of mitotic cell cycle
  + 23 more...
.gamma-tubulin binding
.H4 histone acetyltransferase activity
.H3 histone acetyltransferase activity
  + 2 more...
.protein complex
.BRCA2-MAGE-D1 complex
.secretory granule
  + 4 more...
5 EBI-930865,EBI-743960 KCTD17  
  .protein homooligomerization .identical protein binding .N/A
6 EBI-930865,EBI-740897 NIF3L1  
  .negative regulation of nucleic acid-templated transcription
.positive regulation of transcription, DNA-templated
.neuron differentiation
.identical protein binding
.transcription factor binding
.mitochondrion
.cytoplasm
.nucleus
7 EBI-930865,EBI-739467 GORASP2  
  .organelle organization
.mitotic cell cycle
.N/A .membrane
.Golgi apparatus
.Golgi membrane
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
blood8
embryonic tissue4
eye4
heart11
intestine4
lymph node11
ovary9
testis6
thymus12
vascular19
Health State
TissuesTPM*
normal2
colorectal tumor8
gastrointestinal tumor8
Developmental Stage
TissuesTPM*
adult1
blastocyst16
fetus1
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
appendix1.3
bone marrow4.4
colon1.4
heart muscle3.3
lymph node3.8
ovary1.8
prostate1.3
skin1
small intestine1.6
testis13.1
Tissues
TissuesExpression level
testisMedium
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*602721, gene) Disrupted meiotic cdna 1, yeast, homolog of; DMC1OMIM


#424, YPRC/BPRC, Industry-University Research Center, Yonsei Univ., Seodaemun-gu, Seoul, Korea, 120-749
Tel: +82-2-2123-6626, Fax: +82-2-393-6589
2014-2019 (C) Yonsei Proteome Research Center