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> Protein (NX_Q14574)
Protein (NX_Q14574)
Protein
Gene SymbolDSC3 to neXtProt (NX_Q14574)
DescriptionDesmocollin-3
Chromosome18
Location18q12.1 (28569974 ~ 28622781) to Ensembl
Sequene Features : Isoforms 2, Variants 195, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.protein stabilization
.homophilic cell adhesion via plasma membrane adhesion molecules
.cell adhesion
.in utero embryonic development
.gamma-catenin binding
.calcium ion binding
.desmosome
.integral component of membrane
.membrane
  + 4 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 195 5
2014-09-19protein level
2 142 5
2014-05-27protein level
2 142 6
2014-02-25protein level
2 140 6
2013-12-09protein level
2 110 6
2013-11-01protein level
2 94 5
2013-09-12protein level
2 94 8
2013-08-17protein level
2 94 8
2013-07-15protein level
2 71 8
2013-06-11protein level
2 71 8
2013-02-12protein level
2 37 13
2012-12-20protein level
2 36 13
2012-10-30protein level
2 47 13
2012-10-07protein level
2 47 8
2012-08-24protein level
2 38 8
2012-07-28protein level
2 37 8
2012-06-08protein level
2 37 8
2012-05-07protein level
2 36 8
2012-04-10protein level
2 36 8
2012-01-13protein level
2 21 8
2011-12-20protein level
2 21 8
2011-11-11protein level
2 21 8
2011-08-23protein level
2 21 8
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q14574-1
4 34 4 99905.9644
NX_Q14574-2
0 34 4 93394.9746
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
cervix41
connective tissue576
embryonic tissue4
esophagus49
eye19
heart44
intestine12
kidney4
larynx42
lung2
mammary gland6
mouth287
muscle9
pharynx24
placenta31
prostate10
skin52
testis2
trachea77
uterus4
Health State
TissuesTPM*
normal12
bladder carcinoma56
cervical tumor57
esophageal tumor57
gastrointestinal tumor16
germ cell tumor3
head and neck tumor141
non-neoplasia41
skin tumor15
soft tissue/muscle tissue tumor686
Developmental Stage
TissuesTPM*
adult60
embryoid body14
fetus26
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
esophagus103
placenta15.9
prostate7.2
salivary gland3.5
skin287.6
urinary bladder4.7
Tissues
TissuesExpression level
esophagusHigh
oral mucosaHigh
placentaMedium
skin 1High
skin 2High
tonsilMedium
vaginaHigh
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*600271, gene) Desmocollin 3; DSC3OMIM
2(#613102, phenotype) Hypotrichosis and recurrent skin vesiclesOMIM


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