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> Protein (NX_Q14872)
Protein (NX_Q14872)
Protein
Gene SymbolMTF1 to neXtProt (NX_Q14872)
DescriptionMetal regulatory transcription factor 1
Chromosome1
Location1p34.3 (38275239 ~ 38325292) to Ensembl
Sequene Features : Isoforms 1, Variants 96, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.transition metal ion homeostasis
.response to cadmium ion
.positive regulation of transcription from RNA polymerase II promoter
  + 3 more...
.metal ion binding
.transcription coactivator activity
.sequence-specific DNA binding transcription factor activity
  + 5 more...
.nucleoplasm
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 96 2
2014-09-19protein level
1 71 2
2014-05-27protein level
1 70 2
2014-02-25protein level
1 71 2
2013-12-09protein level
1 58 2
2013-11-01protein level
1 53 2
2013-09-12protein level
1 53 0
2013-08-17protein level
1 53 0
2013-07-15protein level
1 38 0
2013-06-11protein level
1 38 0
2013-02-12protein level
1 15 0
2012-12-20protein level
1 14 0
2012-10-30protein level
1 19 0
2012-10-07protein level
1 19 0
2012-08-24protein level
1 13 0
2012-07-28protein level
1 13 0
2012-06-08protein level
1 14 0
2012-05-07protein level
1 14 0
2012-04-10protein level
1 14 0
2012-01-13protein level
1 10 0
2011-12-20protein level
1 10 0
2011-11-11protein level
1 10 0
2011-08-23protein level
1 10 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q14872-1
21 0 1 80906.0135
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-747024,EBI-541426 AP1M1  
  .membrane organization
.regulation of defense response to virus by virus
.endosome to melanosome transport
  + 5 more...
.N/A .extracellular exosome
.trans-Golgi network membrane
.clathrin-coated endocytic vesicle membrane
  + 6 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
bladder33
blood73
bone13
bone marrow41
brain26
cervix82
connective tissue13
embryonic tissue9
esophagus49
eye67
heart22
intestine17
kidney66
liver24
lung89
lymph22
lymph node55
mammary gland52
mouth30
muscle47
nerve64
ovary19
pancreas60
pharynx24
placenta7
prostate10
skin37
spleen56
stomach41
testis57
thymus37
thyroid21
trachea19
uterus17
vascular19
Health State
TissuesTPM*
normal49
breast (mammary gland) tumor32
cervical tumor115
colorectal tumor8
esophageal tumor57
gastrointestinal tumor25
germ cell tumor37
glioma27
head and neck tumor14
kidney tumor43
leukemia74
liver tumor20
lung tumor19
lymphoma27
non-neoplasia31
ovarian tumor13
pancreatic tumor19
primitive neuroectodermal tumor of the CNS7
skin tumor15
soft tissue/muscle tissue tumor7
uterine tumor22
Developmental Stage
TissuesTPM*
adult35
embryoid body14
neonate32
fetus73
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue4.3
adrenal gland4.2
appendix6.7
bone marrow20.6
cerebral cortex3.3
colon5.2
duodenum2.5
esophagus8.5
gallbladder4
heart muscle2.1
kidney3.8
liver1.8
lung4.7
lymph node4
ovary5.4
pancreas1.9
placenta3.9
prostate3.1
salivary gland2.4
skin3.8
small intestine3
spleen4.3
stomach3
testis9.6
thyroid gland4.1
urinary bladder4.8
Tissues
TissuesExpression level
adrenal glandHigh
appendixMedium
bone marrowLow
breastMedium
bronchusMedium
cerebellumHigh
cerebral cortexHigh
cervix, uterineMedium
colonMedium
duodenumMedium
endometrium 1Medium
endometrium 2Low
epididymisMedium
esophagusMedium
fallopian tubeMedium
gallbladderMedium
heart muscleMedium
hippocampusHigh
kidneyHigh
lateral ventricleHigh
liverMedium
lungMedium
nasopharynxMedium
oral mucosaMedium
ovaryHigh
pancreasMedium
parathyroid glandMedium
placentaMedium
prostateMedium
rectumMedium
salivary glandMedium
seminal vesicleMedium
skeletal muscleMedium
skin 1Low
skin 2High
small intestineMedium
soft tissue 1Low
soft tissue 2Low
stomach 1Medium
stomach 2Medium
testisMedium
thyroid glandMedium
tonsilMedium
urinary bladderHigh
vaginaHigh
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*600172, gene) Metal-regulatory transcription factor 1; MTF1OMIM


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