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> Protein (NX_Q14CS0)
Protein (NX_Q14CS0)
Protein
Gene SymbolUBXN2B to neXtProt (NX_Q14CS0)
DescriptionUBX domain-containing protein 2B
Chromosome8
Location8q12.1 (59323823 ~ 59364060) to Ensembl
Sequene Features : Isoforms 1, Variants 47, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.membrane fusion
.regulation of catalytic activity
.proteasome-mediated ubiquitin-dependent protein catabolic process
  + 3 more...
.ubiquitin binding
.protein phosphatase type 1 regulator activity
.cytosol
.Golgi apparatus
.endoplasmic reticulum
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 47 7
2014-09-19protein level
1 34 7
2014-05-27protein level
1 34 7
2014-02-25protein level
1 34 7
2013-12-09protein level
1 26 7
2013-11-01protein level
1 26 7
2013-09-12protein level
1 26 6
2013-08-17protein level
1 26 6
2013-07-15protein level
1 17 5
2013-06-11protein level
1 17 5
2013-02-12protein level
1 5 6
2012-12-20protein level
1 4 6
2012-10-30protein level
1 6 6
2012-10-07protein level
1 6 6
2012-08-24protein level
1 5 6
2012-07-28protein level
1 5 6
2012-06-08protein level
1 6 6
2012-05-07protein level
1 2 6
2012-04-10protein level
1 2 6
2012-01-13protein level
1 3 6
2011-12-20protein level
1 3 6
2011-11-11protein level
1 3 6
2011-08-23protein level
1 3 6
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q14CS0-1
15 0 0 37053.9276
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-1993619,EBI-748171 CRX  
  .retina development in camera-type eye
.response to stimulus
.positive regulation of photoreceptor cell differentiation
  + 5 more...
.leucine zipper domain binding
.nuclear hormone receptor binding
.sequence-specific DNA binding transcription factor activity
  + 3 more...
.transcription factor complex
.nucleus
2 EBI-1993619,EBI-2864512 MEOX1  
  .sclerotome development
.somite development
.hematopoietic stem cell differentiation
  + 2 more...
.sequence-specific DNA binding
.sequence-specific DNA binding transcription factor activity
.chromatin binding
  + 3 more...
.cytoplasm
.nucleus
3 EBI-1993619,EBI-6509505 INCA1  
  .positive regulation of apoptotic signaling pathway
.negative regulation of cyclin-dependent protein serine/threonine kinase activity
.negative regulation of cell proliferation
.cyclin binding
.cyclin-dependent protein serine/threonine kinase inhibitor activity
.cytoplasm
.nucleus
4 EBI-1993619,EBI-6165879 NGLY1  
  .glycoprotein catabolic process .metal ion binding
.peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity
.cytoplasm
5 EBI-1993619,EBI-10234766 VAT1L  
  .N/A .oxidoreductase activity
.zinc ion binding
.N/A
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
ascites50
blood81
bone69
bone marrow20
brain52
connective tissue6
ear124
embryonic tissue18
eye19
heart33
intestine12
kidney42
liver14
lung23
lymph node22
mammary gland26
mouth45
muscle9
ovary49
pancreas23
placenta14
prostate26
skin14
stomach20
testis27
thymus50
thyroid107
trachea57
uterus38
vascular19
Health State
TissuesTPM*
normal35
adrenal tumor79
breast (mammary gland) tumor21
chondrosarcoma60
colorectal tumor17
gastrointestinal tumor33
germ cell tumor41
glioma37
head and neck tumor59
kidney tumor43
leukemia74
non-neoplasia10
ovarian tumor52
pancreatic tumor19
primitive neuroectodermal tumor of the CNS7
prostate cancer28
retinoblastoma21
skin tumor15
soft tissue/muscle tissue tumor31
uterine tumor66
Developmental Stage
TissuesTPM*
adult31
blastocyst16
neonate32
fetus66
infant42
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue7.7
adrenal gland9.4
appendix13
bone marrow7.6
cerebral cortex16.1
colon9.7
duodenum8.5
esophagus7.6
gallbladder10.4
heart muscle8.3
kidney15.2
liver10
lung9.7
lymph node9.2
ovary10.9
pancreas5.2
placenta7.6
prostate10.7
salivary gland9.2
skin5.6
small intestine9.3
spleen9.8
stomach9.3
testis14.3
thyroid gland16.3
urinary bladder10.9
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*610686, gene) Loc137886 geneOMIM


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