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> Protein (NX_Q15027)
Protein (NX_Q15027)
Protein
Gene SymbolACAP1 to neXtProt (NX_Q15027)
DescriptionArf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1
Chromosome17
Location17p13.1 (7239848 ~ 7254797) to Ensembl
Sequene Features : Isoforms 1, Variants 91, PTMs 13 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.protein transport .zinc ion binding
.GTPase activator activity
.recycling endosome membrane
.membrane
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 91 13
2014-09-19protein level
1 69 13
2014-05-27protein level
1 69 13
2014-02-25protein level
1 69 13
2013-12-09protein level
1 51 13
2013-11-01protein level
1 46 13
2013-09-12protein level
1 46 13
2013-08-17protein level
1 46 13
2013-07-15protein level
1 29 3
2013-06-11protein level
1 29 3
2013-02-12protein level
1 17 3
2012-12-20protein level
1 17 3
2012-10-30protein level
1 22 3
2012-10-07protein level
1 22 3
2012-08-24protein level
1 20 3
2012-07-28protein level
1 20 3
2012-06-08protein level
1 27 3
2012-05-07protein level
1 21 3
2012-04-10protein level
1 21 3
2012-01-13protein level
1 16 3
2011-12-20protein level
1 16 3
2011-11-11protein level
1 16 3
2011-08-23protein level
1 16 3
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q15027-1
33 0 1 81484.5998
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-751746,EBI-401755 GRB2  
  .positive regulation of reactive oxygen species metabolic process
.cellular response to ionizing radiation
.branching involved in labyrinthine layer morphogenesis
  + 25 more...
.ephrin receptor binding
.poly(A) RNA binding
.insulin receptor substrate binding
  + 6 more...
.Grb2-EGFR complex
.extracellular exosome
.vesicle membrane
  + 10 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland60
blood220
bone marrow20
brain5
embryonic tissue4
eye9
heart22
intestine8
kidney9
lung14
lymph225
lymph node89
mouth15
muscle18
nerve64
placenta7
prostate21
spleen18
stomach10
testis18
thymus25
thyroid21
tonsil58
uterus12
vascular19
Health State
TissuesTPM*
normal19
adrenal tumor79
colorectal tumor8
gastrointestinal tumor8
germ cell tumor18
glioma9
head and neck tumor14
leukemia201
lung tumor19
lymphoma138
non-neoplasia10
soft tissue/muscle tissue tumor7
Developmental Stage
TissuesTPM*
adult29
blastocyst16
fetus7
juvenile179
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue6.9
adrenal gland9.1
appendix82.7
bone marrow71.1
cerebral cortex3.9
colon8.5
duodenum18.4
esophagus6.8
gallbladder14.3
heart muscle6.8
kidney4.9
liver3.9
lung18.2
lymph node140.2
ovary4.4
pancreas1.1
placenta3.2
prostate8.7
salivary gland8.2
skin8.1
small intestine21.2
spleen101.5
stomach21.9
testis35.3
thyroid gland4.3
urinary bladder21.6
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*607763, gene) Centaurin, beta-1; CENTB1OMIM


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