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> Protein (NX_Q15276)
Protein (NX_Q15276)
Protein
Gene SymbolRABEP1 to neXtProt (NX_Q15276)
DescriptionRab GTPase-binding effector protein 1
Chromosome17
Location17p13.2 (5185558 ~ 5289129) to Ensembl
Sequene Features : Isoforms 2, Variants 63, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.membrane fusion
.vesicle-mediated transport
.protein transport
  + 2 more...
.protein homodimerization activity
.GTPase activator activity
.recycling endosome
.intracellular membrane-bounded organelle
.endocytic vesicle
  + 2 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 63 7
2014-09-19protein level
2 49 7
2014-05-27protein level
2 49 8
2014-02-25protein level
2 49 8
2013-12-09protein level
2 32 8
2013-11-01protein level
2 30 6
2013-09-12protein level
2 30 6
2013-08-17protein level
2 30 6
2013-07-15protein level
2 16 5
2013-06-11protein level
2 16 5
2013-02-12protein level
2 7 10
2012-12-20protein level
2 7 10
2012-10-30protein level
2 9 10
2012-10-07protein level
2 9 5
2012-08-24protein level
2 9 5
2012-07-28protein level
2 9 5
2012-06-08protein level
2 20 5
2012-05-07protein level
2 14 5
2012-04-10protein level
2 14 5
2012-01-13protein level
2 18 5
2011-12-20protein level
2 18 5
2011-11-11protein level
2 18 5
2011-08-23protein level
2 18 5
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q15276-1
4 42 0 99229.0979
NX_Q15276-2
1 42 0 95420.0306
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-447043,EBI-447609 AP1G1  
  .Golgi to lysosome transport
.membrane organization
.regulation of defense response to virus by virus
  + 8 more...
.GTP-dependent protein binding
.kinesin binding
.Rab GTPase binding
  + 2 more...
.recycling endosome
.perinuclear region of cytoplasm
.intracellular membrane-bounded organelle
  + 13 more...
2 EBI-447043,EBI-373637 AP1G2  
  .membrane organization
.vesicle-mediated transport
.viral process
  + 2 more...
.protein transporter activity .transport vesicle
.AP-1 adaptor complex
.membrane
  + 4 more...
3 EBI-447043,EBI-447404 GGA3  
  .positive regulation of protein catabolic process
.vesicle-mediated transport
.intracellular protein transport
.ADP-ribosylation factor binding .clathrin adaptor complex
.endosome membrane
.trans-Golgi network
4 EBI-447043,EBI-447646 GGA2  
  .vesicle-mediated transport
.intracellular protein transport
.ADP-ribosylation factor binding .clathrin-coated vesicle
.clathrin adaptor complex
.endosome membrane
  + 2 more...
5 EBI-447043,EBI-447141 GGA1  
  .positive regulation of protein catabolic process
.vesicle-mediated transport
.intracellular protein transport
.N/A .intracellular membrane-bounded organelle
.clathrin adaptor complex
.membrane
  + 3 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue155
adrenal gland91
ascites50
bladder100
blood98
bone41
bone marrow164
brain97
cervix103
connective tissue80
ear62
embryonic tissue32
esophagus198
eye9
heart44
intestine116
kidney113
larynx85
liver77
lung11
lymph90
lymph node11
mammary gland211
mouth468
muscle103
nerve64
ovary49
pancreas9
parathyroid339
pharynx73
placenta84
prostate73
salivary gland148
skin14
spleen112
stomach73
testis397
thymus163
thyroid107
tonsil411
trachea135
umbilical cord72
uterus4
vascular19
Health State
TissuesTPM*
normal3
adrenal tumor79
breast (mammary gland) tumor290
cervical tumor115
chondrosarcoma96
colorectal tumor44
esophageal tumor57
gastrointestinal tumor67
germ cell tumor193
glioma18
head and neck tumor276
kidney tumor87
leukemia74
liver tumor52
lung tumor145
lymphoma69
non-neoplasia41
ovarian tumor52
pancreatic tumor19
primitive neuroectodermal tumor of the CNS212
prostate cancer38
retinoblastoma64
skin tumor79
soft tissue/muscle tissue tumor95
uterine tumor11
Developmental Stage
TissuesTPM*
adult82
embryoid body14
blastocyst113
neonate257
fetus113
infant85
juvenile53
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue23.6
adrenal gland24.3
appendix22.6
bone marrow8.6
cerebral cortex41.2
colon17
duodenum13.7
esophagus17.4
gallbladder21.1
heart muscle24.4
kidney20.2
liver16.1
lung16.8
lymph node29.4
ovary18.5
pancreas8.1
placenta24.2
prostate29.1
salivary gland16.3
skin11
small intestine14.8
spleen23.1
stomach19
testis17.2
thyroid gland23.1
urinary bladder22.1
Tissues
TissuesExpression level
adrenal glandMedium
appendixMedium
bone marrowMedium
breastHigh
bronchusMedium
cerebellumMedium
cerebral cortexMedium
cervix, uterineMedium
colonMedium
duodenumMedium
endometrium 1Medium
endometrium 2Medium
epididymisMedium
esophagusMedium
fallopian tubeMedium
gallbladderMedium
heart muscleLow
hippocampusMedium
kidneyMedium
lateral ventricleMedium
liverMedium
lungMedium
lymph nodeHigh
nasopharynxMedium
oral mucosaMedium
ovaryMedium
pancreasMedium
parathyroid glandMedium
placentaMedium
prostateMedium
rectumMedium
salivary glandLow
seminal vesicleMedium
skeletal muscleMedium
skin 1Medium
skin 2Low
small intestineMedium
smooth muscleMedium
soft tissue 1Medium
soft tissue 2Medium
spleenHigh
stomach 1Medium
stomach 2Medium
testisMedium
thyroid glandMedium
tonsilHigh
urinary bladderMedium
vaginaLow
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*603616, gene) Rab gtpase-binding effector protein 1; RABEP1OMIM


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