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> Protein (NX_Q15311)
Protein (NX_Q15311)
Protein
Gene SymbolRALBP1 to neXtProt (NX_Q15311)
DescriptionRalA-binding protein 1
Chromosome18
Location18p11.22 (9475007 ~ 9538114) to Ensembl
Sequene Features : Isoforms 1, Variants 58, PTMs 15 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.regulation of small GTPase mediated signal transduction
.positive regulation of GTPase activity
.regulation of GTPase activity
  + 5 more...
.Rac GTPase binding
.ATPase activity, coupled to movement of substances
.Ral GTPase binding
  + 2 more...
.membrane
.cytosol
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 58 15
2014-09-19protein level
1 40 15
2014-05-27protein level
1 40 15
2014-02-25protein level
1 40 15
2013-12-09protein level
1 31 15
2013-11-01protein level
1 29 14
2013-09-12protein level
1 29 14
2013-08-17protein level
1 29 14
2013-07-15protein level
1 19 13
2013-06-11protein level
1 19 13
2013-02-12protein level
1 10 16
2012-12-20protein level
1 11 16
2012-10-30protein level
1 14 16
2012-10-07protein level
1 14 16
2012-08-24protein level
1 14 16
2012-07-28protein level
1 14 16
2012-06-08protein level
1 14 16
2012-05-07protein level
1 9 16
2012-04-10protein level
1 9 16
2012-01-13protein level
1 7 16
2011-12-20protein level
1 7 16
2011-11-11protein level
1 7 14
2011-08-23protein level
1 7 14
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q15311-1
25 0 0 76015.9673
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-749285,EBI-368321 PPL  
  .keratinization .structural constituent of cytoskeleton .extracellular exosome
.desmosome
.plasma membrane
  + 3 more...
2 EBI-749285,EBI-3913209 CCL20  
  .positive regulation of T cell migration
.cellular response to lipoteichoic acid
.cellular response to lipopolysaccharide
  + 10 more...
.chemokine activity .extracellular space
.extracellular region
3 EBI-749285,EBI-713355 GPS2  
  .negative regulation of JNK cascade
.negative regulation of GTPase activity
.JNK cascade
  + 4 more...
.GTPase inhibitor activity
.transcription corepressor activity
.transcriptional repressor complex
.nucleoplasm
4 EBI-749285,EBI-357849 TNIP1  
  .modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade
.negative regulation of ERK1 and ERK2 cascade
.positive regulation of inflammatory response
  + 9 more...
.mitogen-activated protein kinase binding .cytoplasm
.nucleus
.intracellular
5 EBI-749285,EBI-529518 TAX1BP1  
  .innate immune response
.negative regulation of apoptotic process
.negative regulation of type I interferon production
  + 2 more...
.metal ion binding
.kinase binding
.extracellular exosome
.cytosol
6 EBI-749285,EBI-308614 CEP57  
  .protein homooligomerization
.microtubule anchoring
.fibroblast growth factor receptor signaling pathway
  + 5 more...
.protein homodimerization activity
.fibroblast growth factor binding
.microtubule cytoskeleton
.microtubule
.cytosol
  + 5 more...
7 EBI-749285,EBI-747505 C1orf216  
  .N/A .N/A .N/A
8 EBI-749285,EBI-455078 SMARCE1  
  .negative regulation of transcription, DNA-templated
.ATP-dependent chromatin remodeling
.metabolic process
  + 4 more...
.protein N-terminus binding
.ligand-dependent nuclear receptor binding
.N-acetyltransferase activity
  + 4 more...
.nBAF complex
.npBAF complex
.protein complex
  + 6 more...
9 EBI-749285,EBI-748111 ZNF707  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
10 EBI-749285,EBI-10187270 AMOTL2  
  .hippo signaling
.Wnt signaling pathway
.N/A .recycling endosome
.cytoplasmic vesicle
.apical plasma membrane
  + 2 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
adrenal gland60
ascites75
bladder33
blood65
bone139
bone marrow61
brain13
cervix82
connective tissue20
embryonic tissue70
eye100
heart33
intestine38
kidney75
larynx42
liver68
lung44
lymph67
lymph node111
mammary gland66
mouth226
muscle18
nerve128
ovary19
pancreas32
parathyroid48
pituitary gland181
placenta74
prostate26
skin71
stomach73
testis16
thymus25
thyroid107
uterus64
vascular96
Health State
TissuesTPM*
normal47
adrenal tumor79
breast (mammary gland) tumor85
cervical tumor115
chondrosarcoma181
colorectal tumor35
gastrointestinal tumor59
germ cell tumor41
glioma46
head and neck tumor149
kidney tumor43
leukemia84
liver tumor104
lung tumor38
lymphoma55
ovarian tumor13
pancreatic tumor19
primitive neuroectodermal tumor of the CNS7
prostate cancer38
retinoblastoma129
skin tumor55
soft tissue/muscle tissue tumor47
uterine tumor55
Developmental Stage
TissuesTPM*
adult66
embryoid body85
blastocyst81
fetus44
infant42
juvenile35
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue23.4
adrenal gland18.6
appendix22.4
bone marrow15.6
cerebral cortex22.7
colon27
duodenum15.6
esophagus40
gallbladder21
heart muscle21
kidney42.4
liver10.5
lung21.1
lymph node21
ovary23.2
pancreas6.1
placenta26.7
prostate25
salivary gland15.4
skin43.6
small intestine16.6
spleen21.3
stomach23
testis13.3
thyroid gland22
urinary bladder36
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*605801, gene) Rala-binding protein 1; RALBP1OMIM


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