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> Protein (NX_Q15370)
Protein (NX_Q15370)
Protein
Gene SymbolTCEB2 to neXtProt (NX_Q15370)
DescriptionTranscription elongation factor B polypeptide 2
Chromosome16
Location16p13.3 (2821415 ~ 2827298) to Ensembl
Sequene Features : Isoforms 2, Variants 15, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.cellular response to hypoxia
.regulation of transcription from RNA polymerase II promoter in response to hypoxia
.positive regulation of viral transcription
  + 6 more...
.ubiquitin protein ligase binding .elongin complex
.extracellular exosome
.Cul5-RING ubiquitin ligase complex
  + 4 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 15 3
2014-09-19protein level
2 14 3
2014-05-27protein level
2 14 3
2014-02-25protein level
2 14 3
2013-12-09protein level
2 9 3
2013-11-01protein level
2 9 2
2013-09-12protein level
2 9 2
2013-08-17protein level
2 9 2
2013-07-15protein level
2 6 1
2013-06-11protein level
2 6 1
2013-02-12protein level
1 0 1
2012-12-20protein level
1 0 1
2012-10-30protein level
1 0 1
2012-10-07protein level
1 0 1
2012-08-24protein level
1 0 1
2012-07-28protein level
1 0 1
2012-06-08protein level
1 0 1
2012-05-07protein level
1 6 1
2012-04-10protein level
1 6 1
2012-01-13protein level
1 2 1
2011-12-20protein level
1 2 1
2011-11-11protein level
1 2 1
2011-08-23protein level
1 2 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q15370-1
1 5 0 13124.5142
NX_Q15370-2
3 5 0 17899.7774
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-301238,EBI-301231 TCEB1  
  .cellular response to hypoxia
.regulation of transcription from RNA polymerase II promoter in response to hypoxia
.positive regulation of viral transcription
  + 7 more...
.N/A .elongin complex
.cytosol
.nucleoplasm
2 EBI-301238,EBI-394405 MED8  
  .protein ubiquitination
.gene expression
.transcription initiation from RNA polymerase II promoter
.RNA polymerase II transcription cofactor activity .mediator complex
.nucleoplasm
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
adrenal gland60
ascites50
blood130
bone55
bone marrow164
brain43
connective tissue33
ear186
embryonic tissue89
eye100
heart156
intestine64
kidney56
larynx85
liver141
lung56
lymph22
lymph node22
mammary gland52
mouth30
muscle432
ovary19
pancreas18
parathyroid437
pharynx24
pituitary gland181
placenta31
prostate110
skin47
stomach10
testis62
thyroid42
tonsil58
umbilical cord145
uterus30
vascular58
Health State
TissuesTPM*
normal96
adrenal tumor158
bladder carcinoma56
breast (mammary gland) tumor42
chondrosarcoma12
colorectal tumor71
gastrointestinal tumor16
germ cell tumor26
glioma121
head and neck tumor22
kidney tumor43
leukemia116
liver tumor10
lung tumor19
lymphoma13
non-neoplasia10
ovarian tumor26
pancreatic tumor38
primitive neuroectodermal tumor of the CNS7
prostate cancer86
retinoblastoma86
skin tumor39
soft tissue/muscle tissue tumor55
Developmental Stage
TissuesTPM*
adult80
embryoid body85
blastocyst113
neonate64
fetus82
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue109.5
adrenal gland152
appendix104.5
bone marrow167.5
cerebral cortex107.4
colon121.6
duodenum110.9
esophagus228.7
gallbladder201.2
heart muscle284.7
kidney142.6
liver88.4
lung117.9
lymph node186.5
ovary87.6
pancreas95.1
placenta109.4
prostate114.9
salivary gland252.1
skin135.5
small intestine101.7
spleen90.9
stomach134.4
testis187.3
thyroid gland174.4
urinary bladder225.7
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Disease
No.Disease DescriptionRef.
1(*600787, gene) Transcription elongation factor b, polypeptide 2; TCEB2OMIM


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