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> Protein (NX_Q15762)
Protein (NX_Q15762)
Protein
Gene SymbolCD226 to neXtProt (NX_Q15762)
DescriptionCD226 antigen
Chromosome18
Location18q22.2 (67498394 ~ 67629039) to Ensembl
Sequene Features : Isoforms 1, Variants 59, PTMs 12 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.positive regulation of Fc receptor mediated stimulatory signaling pathway
.regulation of immune response
.positive regulation of natural killer cell mediated cytotoxicity
  + 7 more...
.cell adhesion molecule binding
.protein kinase binding
.integrin binding
.membrane raft
.cell surface
.external side of plasma membrane
  + 2 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 59 12
2014-09-19protein level
1 51 12
2014-05-27protein level
1 51 12
2014-02-25protein level
1 51 12
2013-12-09protein level
1 43 12
2013-11-01protein level
1 40 12
2013-09-12protein level
1 40 12
2013-08-17protein level
1 40 12
2013-07-15protein level
1 29 11
2013-06-11protein level
1 29 11
2013-02-12protein level
1 13 12
2012-12-20protein level
1 13 12
2012-10-30protein level
1 17 12
2012-10-07protein level
1 17 12
2012-08-24protein level
1 15 12
2012-07-28protein level
1 15 12
2012-06-08protein level
1 15 12
2012-05-07protein level
1 15 12
2012-04-10protein level
1 15 12
2012-01-13protein level
1 8 12
2011-12-20protein level
1 8 12
2011-11-11protein level
1 8 12
2011-08-23protein level
1 8 12
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q15762-1
15 0 0 38589.2342
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-4314442,EBI-718419 PVRL2  
  .susceptibility to T cell mediated cytotoxicity
.establishment of mitochondrion localization
.regulation of immune response
  + 22 more...
.cell adhesion molecule binding
.protein homodimerization activity
.identical protein binding
  + 2 more...
.extracellular exosome
.integral component of membrane
.cell surface
  + 4 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
blood24
brain6
heart11
kidney4
liver4
lung5
lymph node11
spleen56
thymus12
trachea19
uterus4
vascular19
Health State
TissuesTPM*
normal3
glioma37
leukemia10
lung tumor9
lymphoma13
Developmental Stage
TissuesTPM*
adult1
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue1.2
adrenal gland1.1
appendix8.2
bone marrow3.5
cerebral cortex1.1
colon2.2
duodenum2.7
esophagus1.6
gallbladder3.9
kidney1.6
liver1.9
lung3.9
lymph node10.8
ovary1.1
salivary gland1.1
small intestine3.6
spleen18.4
stomach3.6
testis1.5
urinary bladder3.9
Tissues
TissuesExpression level
adrenal glandLow
appendixHigh
breastLow
bronchusMedium
cerebral cortexMedium
colonLow
duodenumMedium
endometrium 1Low
endometrium 2Low
epididymisLow
fallopian tubeMedium
gallbladderLow
heart muscleMedium
hippocampusMedium
lateral ventricleLow
lungHigh
lymph nodeHigh
prostateLow
seminal vesicleLow
spleenMedium
stomach 1High
stomach 2High
testisLow
tonsilHigh
urinary bladderLow
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*605397, gene) Cd226 antigen; CD226OMIM


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