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> Protein (NX_Q15836)
Protein (NX_Q15836)
Protein
Gene SymbolVAMP3 to neXtProt (NX_Q15836)
DescriptionVesicle-associated membrane protein 3
Chromosome1
Location1p36.23 (7831329 ~ 7841492) to Ensembl
Sequene Features : Isoforms 1, Variants 12, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.negative regulation of secretion by cell
.membrane fusion
.Golgi to plasma membrane protein transport
  + 11 more...
.SNAP receptor activity
.SNARE binding
.recycling endosome
.intracellular membrane-bounded organelle
.neuron projection
  + 12 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 12 1
2014-09-19protein level
1 10 1
2014-05-27protein level
1 10 6
2014-02-25protein level
1 10 6
2013-12-09protein level
1 9 6
2013-11-01protein level
1 9 4
2013-09-12protein level
1 9 3
2013-08-17protein level
1 9 3
2013-07-15protein level
1 6 3
2013-06-11protein level
1 6 3
2013-02-12protein level
1 4 4
2012-12-20protein level
1 4 4
2012-10-30protein level
1 5 4
2012-10-07protein level
1 5 4
2012-08-24protein level
1 5 4
2012-07-28protein level
1 5 4
2012-06-08protein level
1 5 4
2012-05-07protein level
1 2 4
2012-04-10protein level
1 2 4
2012-01-13protein level
1 2 4
2011-12-20protein level
1 2 4
2011-11-11protein level
1 2 3
2011-08-23protein level
1 2 2
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q15836-1
3 0 1 11301.9184
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-722343,EBI-744942 STX4  
  .positive regulation of protein localization to cell surface
.positive regulation of protein localization to plasma membrane
.regulation of extrinsic apoptotic signaling pathway via death domain receptors
  + 21 more...
.sphingomyelin phosphodiesterase activator activity
.SNAP receptor activity
.SNARE binding
.extracellular exosome
.perinuclear region of cytoplasm
.synapse
  + 19 more...
2 EBI-722343,EBI-747430 BCL2L13  
  .activation of cysteine-type endopeptidase activity involved in apoptotic process
.apoptotic process
.cysteine-type endopeptidase activator activity involved in apoptotic process .mitochondrial membrane
.integral component of membrane
.mitochondrion
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue155
adrenal gland212
ascites75
bladder569
blood114
bone181
bone marrow184
brain225
cervix144
connective tissue268
ear62
embryonic tissue89
esophagus446
eye33
heart55
intestine198
kidney246
larynx127
liver126
lung197
lymph45
lymph node22
mammary gland152
mouth151
muscle112
nerve193
ovary68
pancreas60
parathyroid48
pharynx147
pituitary gland60
placenta137
prostate121
salivary gland49
skin223
spleen168
stomach250
testis117
thymus125
thyroid193
tonsil58
trachea212
umbilical cord363
uterus198
vascular1064
Health State
TissuesTPM*
normal170
adrenal tumor158
bladder carcinoma625
breast (mammary gland) tumor214
cervical tumor173
chondrosarcoma169
colorectal tumor257
esophageal tumor521
gastrointestinal tumor143
germ cell tumor117
glioma139
head and neck tumor112
kidney tumor304
leukemia84
liver tumor156
lung tumor68
lymphoma27
non-neoplasia362
ovarian tumor52
pancreatic tumor76
primitive neuroectodermal tumor of the CNS157
prostate cancer105
skin tumor127
soft tissue/muscle tissue tumor127
uterine tumor66
Developmental Stage
TissuesTPM*
adult131
embryoid body171
blastocyst48
neonate547
fetus68
infant42
juvenile215
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue86.9
adrenal gland79
appendix52.7
bone marrow67
cerebral cortex45.3
colon65.2
duodenum57.2
esophagus83.9
gallbladder70.1
heart muscle62.5
kidney60.3
liver26.6
lung85.2
lymph node42.3
ovary73.1
pancreas15
placenta76.2
prostate52.6
salivary gland33.3
skin56
small intestine65
spleen49.7
stomach57.6
testis46.4
thyroid gland70
urinary bladder88.4
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Disease
No.Disease DescriptionRef.
1(*603657, gene) Vesicle-associated membrane protein 3; VAMP3OMIM


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