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> Protein (NX_Q15973)
Protein (NX_Q15973)
Protein
Gene SymbolZNF124 to neXtProt (NX_Q15973)
DescriptionZinc finger protein 124
Chromosome1
Location1q44 (247285277 ~ 247335318) to Ensembl
Sequene Features : Isoforms 5, Variants 42, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
5 42 0
2014-09-19protein level
5 33 0
2014-05-27transcript level
5 33 0
2014-02-25transcript level
5 33 0
2013-12-09transcript level
5 21 0
2013-11-01transcript level
5 21 0
2013-09-12transcript level
5 21 0
2013-08-17transcript level
5 21 0
2013-07-15transcript level
4 15 0
2013-06-11transcript level
4 15 0
2013-02-12transcript level
4 4 0
2012-12-20transcript level
4 6 0
2012-10-30transcript level
4 10 0
2012-10-07transcript level
4 10 0
2012-08-24transcript level
4 9 0
2012-07-28transcript level
4 7 0
2012-06-08transcript level
4 0 0
2012-05-07transcript level
4 0 0
2012-04-10transcript level
4 0 0
2012-01-13transcript level
4 0 0
2011-12-20transcript level
4 2 0
2011-11-11transcript level
4 2 0
2011-08-23transcript level
4 2 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q15973-1
0 11 2 33829.9903
NX_Q15973-2
0 5 1 17818.5626
NX_Q15973-3
0 13 3 40190.93
NX_Q15973-4
1 10 3 33307.738
NX_Q15973-5
0 3 1 8405.9273
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-2555767,EBI-5661036 FSD2  
  .N/A .N/A .N/A
2 EBI-2555767,EBI-748961 CCNDBP1  
  .regulation of cell cycle
.cell cycle
.N/A .cytoplasm
.nucleoplasm
.nucleus
3 EBI-2555767,EBI-533224 TCF4  
  .protein-DNA complex assembly
.positive regulation of transcription from RNA polymerase II promoter
.positive regulation of transcription, DNA-templated
  + 3 more...
.E-box binding
.protein heterodimerization activity
.bHLH transcription factor binding
  + 9 more...
.transcription factor complex
.nucleus
4 EBI-2555767,EBI-3958099 KRTAP5-9  
  .epidermis development .N/A .keratin filament
5 EBI-2555767,EBI-10172290 KRTAP10-7  
  .N/A .identical protein binding .keratin filament
6 EBI-2555767,EBI-10171774 KRTAP10-8  
  .N/A .N/A .keratin filament
7 EBI-2555767,EBI-10172052 KRTAP10-9  
  .N/A .N/A .keratin filament
8 EBI-2555767,EBI-618309 GOLGA2  
  .negative regulation of protein binding
.mitotic cell cycle
.syntaxin binding
.protein kinase binding
.Golgi cisterna membrane
.ER to Golgi transport vesicle
.cis-Golgi network
  + 4 more...
9 EBI-2555767,EBI-359224 TRAF1  
  .regulation of extrinsic apoptotic signaling pathway
.positive regulation of NF-kappaB transcription factor activity
.signal transduction
  + 2 more...
.thioesterase binding
.ubiquitin protein ligase binding
.zinc ion binding
.tumor necrosis factor receptor binding
.cytoplasm
10 EBI-2555767,EBI-948001 KRT31  
  .epidermis development .structural constituent of cytoskeleton .extracellular exosome
.intermediate filament
.extracellular space
11 EBI-2555767,EBI-10171697 KRT40  
  .N/A .structural molecule activity .intermediate filament
12 EBI-2555767,EBI-6872807 SYCE1  
  .cell division
.synaptonemal complex assembly
.N/A .central element
13 EBI-2555767,EBI-724076 MDFI  
  .trophoblast giant cell differentiation
.embryonic skeletal system morphogenesis
.negative regulation of DNA binding
  + 6 more...
.N/A .cytoplasm
.nucleus
14 EBI-2555767,EBI-10172511 KRTAP4-2  
  .N/A .N/A .keratin filament
15 EBI-2555767,EBI-744794 TSGA10  
  .cell projection assembly
.spermatogenesis
.N/A .neuron projection
.nuclear membrane
.motile cilium
.cytoplasm
16 EBI-2555767,EBI-2212028 SSX2IP  
  .regulation of cell motility
.centrosome organization
.cilium assembly
  + 3 more...
.N/A .protein complex
.ciliary basal body
.centriolar satellite
  + 3 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
brain1
embryonic tissue9
eye9
liver4
lung2
mammary gland13
mouth15
prostate5
testis25
thymus12
uterus4
Health State
TissuesTPM*
normal2
breast (mammary gland) tumor21
gastrointestinal tumor8
germ cell tumor3
glioma9
head and neck tumor7
leukemia10
primitive neuroectodermal tumor of the CNS15
prostate cancer9
retinoblastoma43
Developmental Stage
TissuesTPM*
adult1
embryoid body14
fetus3
infant42
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue2
adrenal gland1.9
appendix4.7
bone marrow1.9
cerebral cortex2.1
colon6.8
duodenum5.2
esophagus1.9
gallbladder2.8
heart muscle1.4
kidney4.1
liver1.1
lung3.4
lymph node4.8
ovary2.2
pancreas1.7
placenta2.7
prostate2.1
salivary gland1
skin1.9
small intestine4.9
spleen4.2
stomach3.7
testis8
thyroid gland3.2
urinary bladder4.2
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*194631, gene) Zinc finger protein 124; ZNF124OMIM


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