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> Protein (NX_Q16585)
Protein (NX_Q16585)
Protein
Gene SymbolSGCB to neXtProt (NX_Q16585)
DescriptionBeta-sarcoglycan
Chromosome4
Location4q12 (52886872 ~ 52904648) to Ensembl
Sequene Features : Isoforms 2, Variants 52, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.vascular smooth muscle cell development
.cardiac muscle cell development
.muscle fiber development
.muscle organ development
.N/A .sarcolemma
.sarcoglycan complex
.dystrophin-associated glycoprotein complex
  + 3 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 52 6
2014-09-19protein level
1 47 6
2014-05-27protein level
1 47 6
2014-02-25protein level
1 46 6
2013-12-09protein level
1 41 6
2013-11-01protein level
1 40 6
2013-09-12protein level
1 40 6
2013-08-17protein level
1 40 6
2013-07-15protein level
1 33 5
2013-06-11protein level
1 33 5
2013-02-12protein level
1 22 5
2012-12-20protein level
1 23 5
2012-10-30protein level
1 24 5
2012-10-07protein level
1 24 5
2012-08-24protein level
1 22 5
2012-07-28protein level
1 22 5
2012-06-08protein level
1 22 5
2012-05-07protein level
1 22 5
2012-04-10protein level
1 22 5
2012-01-13protein level
1 22 5
2011-12-20protein level
1 22 5
2011-11-11protein level
1 22 5
2011-08-23protein level
1 22 5
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q16585-1
3 12 0 34754.5527
NX_Q16585-2
1 12 0 26906.2249
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
bladder33
blood8
bone139
bone marrow41
brain83
connective tissue33
ear62
embryonic tissue46
eye47
heart44
intestine51
kidney42
liver38
lung8
lymph node44
mammary gland33
mouth317
muscle94
nerve64
ovary19
pancreas42
placenta38
prostate10
skin23
spleen18
stomach114
testis25
thymus12
trachea19
uterus34
vascular135
Health State
TissuesTPM*
normal57
breast (mammary gland) tumor42
chondrosarcoma120
colorectal tumor44
gastrointestinal tumor109
germ cell tumor7
glioma223
head and neck tumor156
kidney tumor29
leukemia21
liver tumor10
lymphoma13
non-neoplasia82
ovarian tumor26
pancreatic tumor19
primitive neuroectodermal tumor of the CNS31
skin tumor15
soft tissue/muscle tissue tumor15
uterine tumor44
Developmental Stage
TissuesTPM*
adult64
embryoid body71
blastocyst16
fetus73
infant85
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue29.2
adrenal gland24.8
appendix12.1
cerebral cortex38.7
colon19
duodenum15.2
esophagus25.6
gallbladder24.1
heart muscle48.2
kidney33.6
liver7
lung17.4
lymph node7.2
ovary22.2
pancreas3.8
placenta20.3
prostate24.9
salivary gland11.6
skin6.2
small intestine17.1
spleen10.5
stomach15.9
testis22.4
thyroid gland10.9
urinary bladder26.9
Tissues
TissuesExpression level
adrenal glandLow
bone marrowLow
bronchusLow
cerebral cortexMedium
colonLow
endometrium 2Low
heart muscleHigh
lymph nodeLow
nasopharynxLow
ovaryMedium
skeletal muscleMedium
skin 1Medium
smooth muscleMedium
soft tissue 1Medium
soft tissue 2Low
stomach 1Low
tonsilLow
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*600900, gene) Sarcoglycan, beta; SGCBOMIM
2(#604286, phenotype) Muscular dystrophy, limb-girdle, type 2e; LGMD2EOMIM


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