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> Protein (NX_Q16613)
Protein (NX_Q16613)
Protein
Gene SymbolAANAT to neXtProt (NX_Q16613)
DescriptionSerotonin N-acetyltransferase
Chromosome17
Location17q25.1 (74449433 ~ 74466199) to Ensembl
Sequene Features : Isoforms 2, Variants 29, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.cellular response to cAMP
.response to calcium ion
.response to corticosterone
  + 12 more...
.arylamine N-acetyltransferase activity
.aralkylamine N-acetyltransferase activity
.perinuclear region of cytoplasm
.cytosol
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 29 2
2014-09-19protein level
2 23 2
2014-05-27protein level
2 23 2
2014-02-25protein level
1 22 2
2013-12-09protein level
1 15 2
2013-11-01protein level
1 15 2
2013-09-12protein level
1 15 2
2013-08-17protein level
1 15 2
2013-07-15protein level
1 10 2
2013-06-11protein level
1 10 2
2013-02-12protein level
1 9 2
2012-12-20protein level
1 10 2
2012-10-30protein level
1 10 2
2012-10-07protein level
1 10 2
2012-08-24protein level
1 10 2
2012-07-28protein level
1 10 2
2012-06-08protein level
1 11 2
2012-05-07protein level
1 11 2
2012-04-10protein level
1 11 2
2012-01-13protein level
1 6 2
2011-12-20protein level
1 6 2
2011-11-11protein level
1 5 2
2011-08-23protein level
1 5 2
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q16613-1
0 11 0 23328.7867
NX_Q16613-2
2 11 0 28413.625
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-7451846,EBI-711810 BHLHE40  
  .negative regulation of transcription, DNA-templated
.negative regulation of sequence-specific DNA binding transcription factor activity
.entrainment of circadian clock by photoperiod
  + 4 more...
.E-box binding
.protein heterodimerization activity
.MRF binding
  + 10 more...
.Golgi apparatus
.nucleolus
.nucleoplasm
.nucleus
2 EBI-7451846,EBI-724076 MDFI  
  .trophoblast giant cell differentiation
.embryonic skeletal system morphogenesis
.negative regulation of DNA binding
  + 6 more...
.N/A .cytoplasm
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
eye14
kidney9
ovary9
testis4
Health State
TissuesTPM*
normal2
germ cell tumor3
Developmental Stage
TissuesTPM*
adult3
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
testis1.6
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*600950, gene) Arylalkylamine n-acetyltransferase; AANATOMIM
2(#614163, phenotype) Delayed sleep phase syndrome, susceptibility to; DSPSOMIM


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