Home| Contact Us

HOME SEARCH STATISTICS
> Protein (NX_Q16629)
Protein (NX_Q16629)
Protein
Gene SymbolSRSF7 to neXtProt (NX_Q16629)
DescriptionSerine/arginine-rich splicing factor 7
Chromosome2
Location2p22.1 (38970741 ~ 38978636) to Ensembl
Sequene Features : Isoforms 4, Variants 32, PTMs 14 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.negative regulation of mRNA splicing, via spliceosome
.mRNA 3'-end processing
.gene expression
  + 6 more...
.poly(A) RNA binding
.zinc ion binding
.nucleotide binding
.extracellular exosome
.cytoplasm
.nucleoplasm
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
4 32 14
2014-09-19protein level
4 22 14
2014-05-27protein level
4 22 18
2014-02-25protein level
4 22 18
2013-12-09protein level
4 21 18
2013-11-01protein level
4 21 17
2013-09-12protein level
4 21 22
2013-08-17protein level
4 21 22
2013-07-15protein level
4 14 21
2013-06-11protein level
4 14 21
2013-02-12protein level
3 5 27
2012-12-20protein level
3 5 27
2012-10-30protein level
3 6 27
2012-10-07protein level
3 6 25
2012-08-24protein level
3 1 25
2012-07-28protein level
3 1 25
2012-06-08protein level
3 0 25
2012-05-07protein level
3 0 25
2012-04-10protein level
3 0 25
2012-01-13protein level
3 0 25
2011-12-20protein level
3 1 25
2011-11-11protein level
3 1 25
2011-08-23protein level
3 1 25
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q16629-1
0 5 1 27349.9419
NX_Q16629-2
0 5 1 15563.6674
NX_Q16629-3
0 5 1 15247.4757
NX_Q16629-4
0 5 1 25996.1874
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-398885,EBI-727004 SDCBP  
  .positive regulation of extracellular exosome assembly
.positive regulation of exosomal secretion
.ephrin receptor signaling pathway
  + 9 more...
.protein N-terminus binding
.protein heterodimerization activity
.syndecan binding
  + 4 more...
.blood microparticle
.extracellular exosome
.melanosome
  + 12 more...
2 EBI-398885,EBI-593303 SRPK2  
  .regulation of mRNA splicing, via spliceosome
.positive regulation of cell cycle
.innate immune response
  + 12 more...
.14-3-3 protein binding
.poly(A) RNA binding
.ATP binding
  + 2 more...
.cytoplasm
.nucleolus
.nucleoplasm
.nucleus
3 EBI-398885,EBI-2117026 RBBP6  
  .somite development
.embryonic organ development
.protein ubiquitination involved in ubiquitin-dependent protein catabolic process
  + 2 more...
.poly(A) RNA binding
.ligase activity
.zinc ion binding
.ubiquitin-protein transferase activity
.microtubule organizing center
.cytoplasm
.nucleolus
  + 2 more...
4 EBI-398885,EBI-539478 SRPK1  
  .regulation of mRNA processing
.regulation of mRNA splicing, via spliceosome
.innate immune response
  + 9 more...
.poly(A) RNA binding
.ATP binding
.protein serine/threonine kinase activity
  + 2 more...
.nuclear matrix
.plasma membrane
.endoplasmic reticulum
  + 3 more...
5 EBI-398885,EBI-398874 NXF1  
  .poly(A)+ mRNA export from nucleus
.viral process
.gene expression
.mRNA export from nucleus
.poly(A) RNA binding
.nucleocytoplasmic transporter activity
.mRNA binding
.nucleotide binding
.nuclear inclusion body
.nuclear speck
.cytosol
  + 2 more...
6 EBI-398885,EBI-352851 LUC7L2  
  .mRNA splice site selection .poly(A) RNA binding
.enzyme binding
.mRNA binding
.nuclear speck
.U1 snRNP
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue310
adrenal gland242
ascites200
bladder435
blood163
bone125
bone marrow123
brain190
cervix123
connective tissue67
embryonic tissue244
esophagus198
eye95
heart189
intestine103
kidney227
liver126
lung173
lymph90
lymph node178
mammary gland105
muscle103
nerve128
ovary68
pancreas112
parathyroid48
pharynx147
pituitary gland121
placenta134
prostate142
salivary gland394
skin161
spleen187
stomach62
testis197
thymus238
thyroid85
trachea77
umbilical cord72
uterus198
vascular154
Health State
TissuesTPM*
normal178
adrenal tumor237
bladder carcinoma625
breast (mammary gland) tumor118
cervical tumor144
chondrosarcoma84
colorectal tumor62
esophageal tumor231
gastrointestinal tumor109
germ cell tumor174
glioma65
head and neck tumor14
kidney tumor217
leukemia74
liver tumor114
lung tumor38
lymphoma96
non-neoplasia62
ovarian tumor39
pancreatic tumor66
primitive neuroectodermal tumor of the CNS165
prostate cancer115
retinoblastoma107
skin tumor151
soft tissue/muscle tissue tumor119
uterine tumor221
Developmental Stage
TissuesTPM*
adult115
embryoid body200
blastocyst162
neonate96
fetus193
infant340
juvenile125
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue82.3
adrenal gland77.7
appendix120.8
bone marrow212.5
cerebral cortex55.3
colon80.2
duodenum88.6
esophagus80.2
gallbladder68.1
heart muscle40.5
kidney55.6
liver44.9
lung96.4
lymph node153.3
ovary89.7
pancreas36.2
placenta85.2
prostate81.1
salivary gland56.8
skin81.1
small intestine97.3
spleen99.2
stomach76.8
testis75.9
thyroid gland67.2
urinary bladder79.9
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*600572, gene) Splicing factor, serine/arginine-rich, 7; SRSF7OMIM


#424, YPRC/BPRC, Industry-University Research Center, Yonsei Univ., Seodaemun-gu, Seoul, Korea, 120-749
Tel: +82-2-2123-6626, Fax: +82-2-393-6589
2014-2019 (C) Yonsei Proteome Research Center