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> Protein (NX_Q16787)
Protein (NX_Q16787)
Protein
Gene SymbolLAMA3 to neXtProt (NX_Q16787)
DescriptionLaminin subunit alpha-3
Chromosome18
Location18q11.2 (21269407 ~ 21535030) to Ensembl
Sequene Features : Isoforms 4, Variants 483, PTMs 68 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.regulation of embryonic development
.endodermal cell differentiation
.cell junction assembly
  + 7 more...
.structural molecule activity .extracellular exosome
.laminin-5 complex
.laminin-1 complex
  + 2 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
4 483 68
2014-09-19protein level
4 360 68
2014-05-27protein level
4 360 68
2014-02-25protein level
4 357 68
2013-12-09protein level
4 250 68
2013-11-01protein level
4 242 68
2013-09-12protein level
4 242 68
2013-08-17protein level
4 242 68
2013-07-15protein level
3 175 67
2013-06-11protein level
3 175 67
2013-02-12protein level
3 90 148
2012-12-20protein level
3 84 148
2012-10-30protein level
3 119 148
2012-10-07protein level
3 119 65
2012-08-24protein level
3 113 65
2012-07-28protein level
3 113 65
2012-06-08protein level
3 122 65
2012-05-07protein level
3 98 65
2012-04-10protein level
2 98 65
2012-01-13protein level
2 51 65
2011-12-20protein level
2 51 65
2011-11-11protein level
2 51 65
2011-08-23protein level
2 51 65
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q16787-1
0 80 0 190371.6478
NX_Q16787-2
0 161 1 366413.0022
NX_Q16787-3
0 159 1 359979.7613
NX_Q16787-4
0 78 0 183938.4069
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
bladder100
bone27
brain3
connective tissue26
embryonic tissue4
esophagus446
eye38
heart44
intestine51
kidney9
larynx213
liver24
lung29
mammary gland13
mouth967
muscle56
ovary9
pancreas32
parathyroid48
pharynx98
placenta38
prostate47
skin33
stomach41
testis16
thymus12
thyroid21
trachea57
uterus116
Health State
TissuesTPM*
normal18
bladder carcinoma170
breast (mammary gland) tumor10
chondrosarcoma72
colorectal tumor97
esophageal tumor521
gastrointestinal tumor33
head and neck tumor515
kidney tumor14
lung tumor29
lymphoma13
non-neoplasia41
ovarian tumor13
pancreatic tumor47
primitive neuroectodermal tumor of the CNS23
prostate cancer57
retinoblastoma21
skin tumor23
uterine tumor244
Developmental Stage
TissuesTPM*
adult79
embryoid body14
fetus16
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue7.2
adrenal gland1.8
appendix10.7
cerebral cortex1.7
colon16.2
duodenum18.1
esophagus9.5
gallbladder9.3
heart muscle2.1
kidney1.7
liver1.6
lung27.5
lymph node6.5
ovary5.4
pancreas2.8
placenta28.2
prostate8.6
salivary gland10.9
skin24.3
small intestine19.6
spleen1
stomach35
testis4
urinary bladder7.9
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(#226700, phenotype) Epidermolysis bullosa, junctional, herlitz typeOMIM
2(#245660, phenotype) Laryngoonychocutaneous syndrome; LOCSOMIM
3(*600805, gene) Laminin, alpha-3; LAMA3OMIM


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