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> Protein (NX_Q16820)
Protein (NX_Q16820)
Protein
Gene SymbolMEP1B to neXtProt (NX_Q16820)
DescriptionMeprin A subunit beta
Chromosome18
Location18q12.1 (29765032 ~ 29800367) to Ensembl
Sequene Features : Isoforms 1, Variants 95, PTMs 21 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.toxin transport
.digestion
.inflammatory response
.zinc ion binding
.metalloendopeptidase activity
.integral component of plasma membrane
.plasma membrane
.extracellular space
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 95 21
2014-09-19protein level
1 73 21
2014-05-27protein level
1 73 21
2014-02-25protein level
1 72 21
2013-12-09protein level
1 50 21
2013-11-01protein level
1 50 21
2013-09-12protein level
1 50 21
2013-08-17protein level
1 50 21
2013-07-15protein level
1 33 21
2013-06-11protein level
1 33 21
2013-02-12protein level
1 19 21
2012-12-20protein level
1 17 17
2012-10-30protein level
1 26 17
2012-10-07protein level
1 26 17
2012-08-24protein level
1 26 17
2012-07-28protein level
1 26 17
2012-06-08protein level
1 31 17
2012-05-07protein level
1 24 17
2012-04-10protein level
1 24 17
2012-01-13protein level
1 14 17
2011-12-20protein level
1 14 17
2011-11-11protein level
1 14 17
2011-08-23protein level
1 14 17
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q16820-1
28 0 0 79520.4096
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-968418,EBI-1382326 MMP9  
  .negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
.negative regulation of cation channel activity
.negative regulation of intrinsic apoptotic signaling pathway
  + 19 more...
.identical protein binding
.zinc ion binding
.metallopeptidase activity
  + 3 more...
.extracellular exosome
.extracellular space
.proteinaceous extracellular matrix
.extracellular region
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
intestine47
lymph45
muscle9
stomach10
thyroid21
Health State
TissuesTPM*
normal3
gastrointestinal tumor8
head and neck tumor7
lymphoma27
Developmental Stage
TissuesTPM*
adult1
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
colon9.3
duodenum203.9
liver4.6
small intestine290
Tissues
TissuesExpression level
colonLow
duodenumHigh
small intestineHigh
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*600389, gene) Meprin, beta subunit; MEP1BOMIM


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