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> Protein (NX_Q18PE1)
Protein (NX_Q18PE1)
Protein
Gene SymbolDOK7 to neXtProt (NX_Q18PE1)
DescriptionProtein Dok-7
Chromosome4
Location4p16.3 (3465033 ~ 3503200) to Ensembl
Sequene Features : Isoforms 4, Variants 123, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.positive regulation of protein tyrosine kinase activity
.receptor clustering
.neuromuscular junction development
.phosphatidylinositol binding
.protein kinase binding
.neuromuscular junction
.cell junction
.plasma membrane
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
4 123 2
2014-09-19protein level
4 103 2
2014-05-27protein level
4 101 2
2014-02-25protein level
4 101 2
2013-12-09protein level
4 76 2
2013-11-01protein level
4 75 2
2013-09-12protein level
4 75 2
2013-08-17protein level
4 75 2
2013-07-15protein level
3 59 2
2013-06-11protein level
3 59 2
2013-02-12protein level
3 55 0
2012-12-20protein level
3 56 0
2012-10-30protein level
3 55 0
2012-10-07protein level
3 36 0
2012-08-24protein level
3 36 0
2012-07-28protein level
3 36 0
2012-06-08protein level
3 40 0
2012-05-07protein level
3 36 0
2012-04-10protein level
3 36 0
2012-01-13protein level
3 24 0
2011-12-20protein level
3 24 0
2011-11-11protein level
3 27 0
2011-08-23protein level
3 27 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q18PE1-1
0 19 0 53063.469
NX_Q18PE1-2
3 10 0 37137.9691
NX_Q18PE1-3
5 19 0 63897.8744
NX_Q18PE1-4
3 8 0 27496.205
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
blood8
brain10
eye9
ovary19
testis2
Health State
TissuesTPM*
normal8
breast (mammary gland) tumor32
kidney tumor14
ovarian tumor39
skin tumor7
soft tissue/muscle tissue tumor7
uterine tumor44
Developmental Stage
TissuesTPM*
adult2
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
heart muscle13.9
kidney1.5
lung2.7
lymph node2.2
pancreas2.8
prostate1.3
spleen1.5
stomach2.2
testis3.9
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(#254300, phenotype) Myasthenia, limb-girdle, familialOMIM
2(*610285, gene) Downstream of tyrosine kinase 7; DOK7OMIM


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