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> Protein (NX_Q2NKX8)
Protein (NX_Q2NKX8)
Protein
Gene SymbolERCC6L to neXtProt (NX_Q2NKX8)
DescriptionDNA excision repair protein ERCC-6-like
ChromosomeX
LocationXq13.1 (71424510 ~ 71458897) to Ensembl
Sequene Features : Isoforms 1, Variants 110, PTMs 21 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.cell division
.small GTPase mediated signal transduction
.mitotic nuclear division
.mitotic cell cycle
.ATP binding
.helicase activity
.DNA binding
.membrane
.plasma membrane
.cytosol
  + 4 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 110 21
2014-09-19protein level
1 86 21
2014-05-27protein level
1 86 21
2014-02-25protein level
1 86 21
2013-12-09protein level
1 72 21
2013-11-01protein level
1 70 20
2013-09-12protein level
1 70 21
2013-08-17protein level
1 70 21
2013-07-15protein level
1 44 20
2013-06-11protein level
1 44 20
2013-02-12protein level
1 22 32
2012-12-20protein level
1 23 32
2012-10-30protein level
1 27 32
2012-10-07protein level
1 27 32
2012-08-24protein level
1 20 32
2012-07-28protein level
1 20 32
2012-06-08protein level
1 27 32
2012-05-07protein level
1 27 32
2012-04-10protein level
1 27 32
2012-01-13protein level
1 10 32
2011-12-20protein level
1 10 32
2011-11-11protein level
1 10 31
2011-08-23protein level
1 10 31
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q2NKX8-1
59 0 0 141014.9449
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-1042535,EBI-466029 HTT  
  .negative regulation of extrinsic apoptotic signaling pathway
.iron ion homeostasis
.L-glutamate import
  + 38 more...
.diazepam binding
.beta-tubulin binding
.dynein intermediate chain binding
  + 6 more...
.protein complex
.cytoplasmic vesicle membrane
.dendrite
  + 11 more...
2 EBI-1042535,EBI-2798728 LMO4  
  .regulation of cell activation
.thymus development
.positive regulation of transcription from RNA polymerase II promoter
  + 8 more...
.zinc ion binding
.transcription factor binding
.sequence-specific DNA binding transcription factor activity
.enhancer sequence-specific DNA binding
.transcription factor complex
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
bone41
bone marrow20
brain1
embryonic tissue32
intestine4
kidney9
liver14
lung2
lymph node44
mammary gland46
muscle9
ovary39
prostate10
skin9
testis13
thymus12
uterus17
vascular19
Health State
TissuesTPM*
normal6
breast (mammary gland) tumor53
chondrosarcoma36
germ cell tumor26
kidney tumor14
leukemia10
liver tumor31
ovarian tumor52
primitive neuroectodermal tumor of the CNS31
prostate cancer19
skin tumor15
soft tissue/muscle tissue tumor31
Developmental Stage
TissuesTPM*
adult12
embryoid body14
blastocyst65
fetus5
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
appendix1.5
bone marrow2
colon1.1
lymph node2.4
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*300687, gene) Ercc6-like; ERCC6LOMIM


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