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> Protein (NX_Q2TAZ0)
Protein (NX_Q2TAZ0)
Protein
Gene SymbolATG2A to neXtProt (NX_Q2TAZ0)
DescriptionAutophagy-related protein 2 homolog A
Chromosome11
Location11q13.1 (64662007 ~ 64684722) to Ensembl
Sequene Features : Isoforms 4, Variants 228, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.nucleophagy
.cellular response to nitrogen starvation
.mitochondrion degradation
.autophagic vacuole assembly
.N/A .pre-autophagosomal structure membrane
.extrinsic component of membrane
.lipid particle
.pre-autophagosomal structure
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
4 228 5
2014-09-19protein level
4 171 5
2014-05-27protein level
4 170 5
2014-02-25protein level
4 169 5
2013-12-09protein level
4 122 5
2013-11-01protein level
4 118 5
2013-09-12protein level
4 118 5
2013-08-17protein level
4 118 5
2013-07-15protein level
4 86 5
2013-06-11protein level
4 86 5
2013-02-12protein level
4 47 8
2012-12-20protein level
4 48 8
2012-10-30protein level
4 53 8
2012-10-07protein level
4 53 4
2012-08-24protein level
4 42 4
2012-07-28protein level
4 42 4
2012-06-08protein level
4 43 4
2012-05-07protein level
4 43 4
2012-04-10protein level
4 43 4
2012-01-13protein level
4 24 4
2011-12-20protein level
4 24 4
2011-11-11protein level
4 24 4
2011-08-23protein level
4 24 4
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q2TAZ0-1
1 80 1 212725.7153
NX_Q2TAZ0-3
1 80 1 212952.8416
NX_Q2TAZ0-4
5 11 0 35232.6126
NX_Q2TAZ0-5
2 4 0 13567.011
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-2514077,EBI-712001 GABARAP  
  .membrane fusion
.nucleophagy
.extrinsic apoptotic signaling pathway via death domain receptors
  + 5 more...
.GABA receptor binding
.beta-tubulin binding
.microtubule binding
.perinuclear region of cytoplasm
.cell body
.cytoplasmic vesicle
  + 13 more...
2 EBI-2514077,EBI-720116 GABARAPL2  
  .negative regulation of proteasomal protein catabolic process
.membrane fusion
.nucleophagy
  + 7 more...
.ATPase binding
.GABA receptor binding
.beta-tubulin binding
  + 2 more...
.cytoplasmic vesicle
.extrinsic component of membrane
.cytosol
  + 7 more...
3 EBI-2514077,EBI-373144 MAP1LC3B  
  .regulation of mitochondrion degradation
.membrane fusion
.nucleophagy
  + 3 more...
.microtubule binding .cytoplasmic vesicle
.organelle membrane
.extrinsic component of membrane
  + 9 more...
4 EBI-2514077,EBI-746969 GABARAPL1  
  .membrane fusion
.nucleophagy
.mitochondrion degradation
.autophagic vacuole assembly
.GABA receptor binding
.beta-tubulin binding
.Tat protein binding
.microtubule binding
.cell body
.dendrite cytoplasm
.dendrite membrane
  + 10 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue155
bladder33
blood32
bone41
bone marrow20
brain17
cervix61
connective tissue6
embryonic tissue4
eye43
intestine25
kidney14
liver14
lung11
lymph112
lymph node44
muscle18
ovary29
pancreas18
placenta7
prostate15
salivary gland49
skin37
stomach31
testis13
thymus50
thyroid21
uterus30
Health State
TissuesTPM*
normal11
bladder carcinoma56
cervical tumor86
chondrosarcoma12
colorectal tumor26
gastrointestinal tumor25
germ cell tumor18
glioma55
head and neck tumor14
kidney tumor29
leukemia52
liver tumor20
lung tumor19
lymphoma69
ovarian tumor13
pancreatic tumor19
primitive neuroectodermal tumor of the CNS31
prostate cancer19
retinoblastoma86
skin tumor47
soft tissue/muscle tissue tumor15
uterine tumor66
Developmental Stage
TissuesTPM*
adult15
blastocyst16
fetus5
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue5.4
adrenal gland4.4
appendix5.8
bone marrow31.6
cerebral cortex5.1
colon5.4
duodenum6.4
esophagus3.6
gallbladder4.5
heart muscle3.4
kidney6.4
liver6.2
lung5.4
lymph node5.4
ovary5.9
pancreas3.8
placenta4.9
prostate5.9
salivary gland4.8
skin6.9
small intestine6.2
spleen8.8
stomach6.5
testis6.7
thyroid gland4.7
urinary bladder4.2
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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